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Table 2 Multivariate Cox regression analysis for survival in patients with lung adenocarcinoma

From: Tumor microenvironment-associated lactate metabolism regulates the prognosis and precise checkpoint immunotherapy outcomes of patients with lung adenocarcinoma

Variables

Multivariate analysis

P-value

Hazard ratio

Lower 95%CI

Upper 95%CI

Lactate-related risk score

340.00

40.00

2900.00

< 0.0001***

Age (≥ 60 vs. < 60)

1.20

0.86

1.60

0.30

Gender (male vs. female)

0.98

0.74

1.30

0.87

Pathological stage (III–IV vs. I–II)

2.10

1.00

4.10

0.036*

Distant metastasis (M1 vs. M0)

0.82

0.37

1.80

0.62

Lymph node metastasis (N2-3 vs. N0-1)

0.92

0.47

1.80

0.80

Tumor invasion (T1-2 vs. T3-4)

0.72

0.11

4.60

0.73

Previous radiation therapy (yes vs. no)

1.50

1.10

2.20

0.02

  1. CI confidence interval
  2. *P < 0.05; **P < 0.01; ***P < 0.001