Identification of significant modules and hub genes involved in hepatic encephalopathy using WGCNA

Table 1 Top 10 significant drugs targeting the genes in brown module

Term	p-value	q-value	overlap_genes
Tamibarotene CTD 00002527	0.000013	0.003889	[HLA-DMB, ALOX5AP, CYBB, CYBA, LGALS9, AIF1]
leukotriene C4 CTD 00007223	0.000128	0.019335	[SYK, ALOX5AP]
dioxidanide CTD 00006819	0.000620	0.062370	[CYBB, CYBA]
valproic acid HL60 DOWN	0.000921	0.066995	[SYK, PTPN6, LAIR1]
Sodium dichromate CTD 00000827	0.001109	0.066995	[SLC7A7, AIF1, LAIR1]
TACROLIMUS MONOHYDRATE CTD 00007118	0.001519	0.076433	[CYBA, CCR3]
NADP( +) BOSS	0.003302	0.132900	[CYBB, CYBA]
pergolide HL60 UP	0.003521	0.132900	[RBM47, FCGR2A, CYBB]
mebendazole HL60 UP	0.004703	0.157814	[RBM47, FCGR2A, SLC7A7]
Medroxyprogesterone acetate CTD 00006623	0.006509	0.166665	[C1QA, ALOX5AP, AIF1]

ISSN: 2047-783X