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Table 1 Serum Ca2+, P3+, and osteocalcin levels in osteoporosed rat model treated with olive oil and Lepidium sativum, individually and in combination, using alendronate as authenticated drug for treatment of osteoporosis

From: The combination of olive oil and Lepidium sativum improves the deleterious effects resulting from dexamethasone-induced osteoporosis in rats

Group

Control (n = 8)

Osteoporosis (n = 8)

Alendronate (n = 8)

Olive oil (n = 8)

L. sativum (n = 8)

Olive oil + Lepidium sativum (n = 8)

Calcium

9.53 ± 0.21

7.74 ± 0.09*

9.88 ± 0.20#

10.35 ± 0.34#

10.14 ± 0.22#

10.91 ± 0.31#&

Phosphorous

5.26 ± 0.19

3.7 ± 0.18*

4.83 ± 0.15#

5.69 ± 0.58#&

5.33 ± 0.14#

6.08 ± 0.09#&

Osteocalcin

1.81 ± 0.09

1.04 ± 0.05*

2.13 ± 0.13#

2.13 ± 0.13#

2.13 ± 0.08#

2.25 ± 0.13#

  1. Ca2+, P3+, and osteocalcin were measured in 8 rats per group in triplicates. Data presented as mean ± SEM
  2. Data represented as mean ± SEM
  3. *Significant results as compared to control group
  4. #Significant results as compared to osteoporosed group
  5. &Significant results as compared to alendronate drug group
  6. *, #, &Depicts significance at p < 0.05