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Table 1 Demographic, clinical, and laboratory characteristics of COVID-19 patients significantly associated with mortality, stratified by the outcome of hospitalization

From: A novel scoring system for early assessment of the risk of the COVID-19-associated mortality in hospitalized patients: COVID-19 BURDEN

Variable

Discharged (n = 312)

Expired (n = 168)

P value

Cutoff set for ratio variables

Age Mean (SD)

57.03 (15.759)

66.80 (13.930)

 < 0.0001

 < 60

 > = 60

HTN (present:absent)

115:197

80:88

0.025

IHD (present:absent)

43:269

40:128

0.008

N/V (present:absent)

75:236

27:140

0.047

Systolic BP

127.97 (19.083)

123.05 (24.884)

0.026

 > 114

 <  = 114

Diastolic BP

79.44 (11.350)

75.06 (13.180)

0.001

 > 75

 <  = 75

RR

20.50 (4.715)

23.86 (7.436)

 < 0.0001

 <  = 20

 > 20

O2 Sat

84.63 (10.539)

70.42 (16.926)

 < 0.0001

 > 90

83–90

 <  = 83

WBC

7.7684 (4.17933)

10.1776 (5.87533)

 < 0.0001

 <  = 7.52

 > 7.52

ANC

6045.06 (3850.1621)

8573.50 (5173.281)

 < 0.0001

 > 5628

 <  = 5627

PT

32.92 (23.700)

42.31 (26.991)

 < 0.0001

 <  = 16.2

 > 16.2

BUN

21.16 (26.450)

34.76 (24.786)

 < 0.0001

 <  = 23

 > 23

Cr

1.4259 (1.46007)

1.9012 (1.81179)

0.002

 <  = 1.3

 > 1.3

K

4.452 (0.5787)

4.811 (0.8522)

 < 0.0001

 <  = 4.9

 > 4.9

AST

67.74 (99.519)

116.94 (305.125)

0.015

 <  = 67

 > 67

Alb

3.748 (0.3469)

3.446 (0.4644)

 < 0.0001

 > 3.7

 <  = 3.7

CPK

218.35 (312.488)

634.76 (1432.796)

 < 0.0001

 <  = 78

 > 78

LDH

742.83 (561.077)

1055.28 (637.258)

 < 0.0001

 <  = 731

 > 731

CRP

64.39 (50.420)

72.99 (21.225)

0.049

 <  = 73.1

 > 73.1

  1. These variables entered multivariate logistic regression analysis. HTN hypertension, IHD ischemic heart disease, N/V nausea and/or vomiting, BP blood pressure, RR respiratory rate, O2 Sat O2 saturation, WBC white blood cell count, ANC absolute neutrophil count, PT prothrombin time, BUN blood urea nitrogen, Cr creatinine, K potassium, AST aspartate transaminase, Alb albumin, CPK creatinine phosphokinase, LDH lactate dehydrogenase, CRP C-reactive protein