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Table 2 RBE values carbon ion/proton in prostate cancer cell lines

From: Does particle radiation have superior radiobiological advantages for prostate cancer cells? A systematic review of in vitro studies

Author, year

RBE model

RBE value

Konings 2019

L–Q

PC-3: 0.94 (proton) and 1.93 (carbon ion)

Butterworth 2012

Not reported

DU-145: 1.1

Khachonkham 2020

L–Q

DU-145: 1.28 ± 0.25, 1.37 ± 0.17 and 1.52 ± 0.17 (within SOBP); 1.27 ± 0.27, 0.97 ± 0.4 (before peak)a

Tinganelli 2013

L–Q

RAT-1: 2.8 ± 0.2 (oxic) and 3.7 ± 0.1 (anoxic)

Polf 2011

L–Q

DU-145: 1.3 (untreated) and 1.5 (Au-treated)

Suetens 2015

L–Q

PC-3: 1.67

  1. RBE relative biological effectiveness, L–Q linear–quadratic
  2. a Data were from RBE10, RBE2Gy and RBE4Gy were not shown in this table