Does particle radiation have superior radiobiological advantages for prostate cancer cells? A systematic review of in vitro studies

Table 5 SER values of combination therapy and OER

Author, year	Combination therapy (Dose)	Cell line	SER
Author, year	Combination therapy (Dose)	Cell line	Carbon ion irradiation	Proton irradiation	Photon irradiation
Konings 2019	GANT61 10 μM	PC-3	1.09	0.98	1.07
Srivastava 2018	PNKPi 0.5 μM PNKPi 1.0 μM PNKPi 5 μM PNKPi 10 μM	PC-3 PC-3 PC-3 PC-3	1.21 1.29 1.47 2.05	NA NA NA NA	NA NA NA NA
Polf 2011	Gold nanoparticles	DU-145		1.15
			OER
Tinganelli 2013	NA	RAT-1	1.77 ± 0.13	NA	2.32 ± 0.04

SER standard enhancement ratio, OER oxygen enhancement ratio, GANT61 GLI antagonist, PNKPi polynucleotide kinase/phosphatase inhibitor, NA not available

ISSN: 2047-783X