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Table 3 Predictors of poor renal evolution at 6 months

From: Searching for a prognostic index in lupus nephritis

Predictor

Bivariate

OR [CI 95%]

P value

Age of onset (years)

1.05 [1.01–1.09]

0.020**

 Time to kidney biopsy (months)

1.00 [0.99–1.01]

0.496

 Woman (%)

0.32 [0.09–1.18]

0.088

 SLEDAI

0.94 [0.86–1.03]

0.192

 Creatinine mg/dl

1.61 [0.85–3.03]

0.140

 Glomerular filtrate rate (ml/in/1.73m2)

0.98 [0.97–1.00]

0.110

 Proteinuria (g/24 h)

0.80 [0.59–1.08]

0.147

Renal chronicity index

1.67 [1.16–2.42]

0.006 **

 Extrarenal manifestations

2.19 [0.44–11.0]

0.338

Thrombocytopenia*

5.67 [1.19–26.9]

0.029 **

 Low C3

0.33 [0.10–1.06]

0.063

 Previous antimalarial treatment

0.48 [0.14–1.61]

0.233

 Previous glucocorticoids treatment

0.63 [0.15–2.61]

0.526

 Previous immunosuppressor treatment

1.33 [0.35–5.01]

0.670

Interstitial fibrosis

4.44 [1.33–14.9]

0.016 **

Tubular atrophy

4.33 [1.29–14.5]

0.018 **

  1. SLEDAI Systemic Lupus Erythematosus Disease Activity Index; **: statistically significant
  2. * < 50.000 platelets/mm