The value of serum IL-4 to predict the survival of MDS patients

Table 3 Univariate and multivariate analysis

Factors	Univariate analysis		Multivariate analysis
Factors	HR (95% CI)	P	HR (95% CI)	P
Male	1.820 (0.560–5.915)	0.319
Age ≥ 65	0.342 (0.120–0.973)	0.044	0.362 (0.141–0.977)	0.045
HB ≥ 100 g/L	0.256 (0.032–2.045)	0.199
N ≥ 0.8*109/L	1.946 (0.525–7.208)	0.319
PLT ≥ 100*109/L	1.092 (0.379–3.144)	0.870
Cytopenia series ≥ 2	0.211 (0.117–1.605)	0.211
Bone marrow primitive cell ratio ≥ 2%	0.736 (0.244–2.216)	0.586
Karyotype: bad	0.665 (0.236–1.876)	0.441
IL-4	0.172 (0.061–0.487)	0.001	0.237 (0.114–0.779)	0.013

HB: hemoglobin, N: neutrophil, PLT: platelet, karyotype good: − Y, 11q⁻ (excellent); normal karyotype, 5q⁻, 12p⁻, 20q⁻, 5q⁻ with another karyotype abnormality attached (good); 7q⁻, + 8, + 19, i (17q), chromosomal abnormalities in other or 2 independent clones (moderate). Karyotype bad: − 7, inv(3)/t(3q)/dcl(3q), − 7/7q⁻ with one additional abnormality, 3 complex abnormalities (poor), ≥ 3 complex abnormalities (very poor)

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