Table 2 Univariate analysis of continuous variables at 1 h and 1 day after extubation
Time to death < 1 h (76) | Time to death ≧ 1 h (64) | pa | Time to death < 1 day (105) | Time to death ≧1 day (35) | pa | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Median | IQR | Min–max | Median | IQR | Min–max | Median | IQR | Min–max | Median | IQR | Min–max | |||
Baseline characteristics | ||||||||||||||
Age (years) | 64.5 | 20 | 19–94 | 68 | 20.8 | 35–93 | 0.343 | 67 | 20.5 | 19–94 | 66 | 20 | 37–91 | 0.922 |
Intubation (days) | 14 | 13 | 0–65 | 16 | 15 | 1–62 | 0.156 | 14 | 13 | 0–65 | 17 | 16 | 3–62 | 0.116 |
Intubation to family meeting (days) | 13 | 12 | 0–62 | 14 | 15.8 | 1–62 | 0.412 | 13 | 12 | 0–62 | 14 | 17 | 1–62 | 0.329 |
GCS (total) | 3 | 2.8 | 3–10 | 6 | 2 | 3–11 |  < 0.001 | 3 | 3 | 3–1 | 6 | 4 | 3–9 | 0.040 |
Vital signs from monitor | ||||||||||||||
SBP (mmHg) | 98.5 | 40.5 | 35–165 | 111 | 41.5 | 53–179 | 0.179 | 101 | 39.0 | 35–169 | 116 | 54.0 | 61–179 | 0.040 |
DBP (mmHg) | 51 | 21.0 | 12–110 | 57 | 27 | 39–105 | 0.029 | 51 | 19.0 | 12–110 | 67 | 25.0 | 43–97 |  < 0.001 |
MAP (mmHg) | 66 | 28.8 | 0–128.3 | 74.3 | 30.4 | 44–125.3 | 0.029 | 66 | 26.0 | 0–128.3 | 83 | 34.3 | 56–111.7 | 0.011 |
Pulse rate (/min) | 84 | 47.5 | 26–155 | 97 | 23.8 | 50–164 | 0.007 | 89 | 43.0 | 26–164 | 96 | 23.0 | 57–126 | 0.205 |
Pulse oximetry (SpO2, %) | 95 | 16 | 0–100 | 97 | 4 | 55–100 | 0.109 | 95 | 13 | 0–100 | 97 | 4 | 57–100 | 0.008 |
Respiratory variables | ||||||||||||||
Respiratory rate (/min) | 15 | 9.8 | 0–50 | 20 | 8 | 0–45 |  < 0.001 | 16 | 10.5 | 0–50 | 18 | 8.0 | 11–45 | 0.241 |
FiO2 from ventilator (%) | 60 | 65 | 21–100 | 30 | 5 | 21–100 |  < 0.001 | 45 | 55 | 21–100 | 25 | 9 | 21–45 |  < 0.001 |
PEEP (cmH2O) | 8 | 3 | 5–14 | 5 | 3 | 5–13 | 0.003 | 8 | 3 | 5–14 | 5 | 1 | 5–8 |  < 0.001 |
Static pressure (cmH2O) | 26 | 9.0 | 5–43 | 22 | 8.8 | 7–41 | 0.011 | 25 | 9.0 | 5–43 | 21 | 9.0 | 7–31 | 0.019 |
Minute ventilation (L/min) | 10.3 | 4.5 | 3.5–19.6 | 5.9 | 2.3 | 2.1–16.3 |  < 0.001 | 9.29 | 4.9 | 3.5–19.6 | 5.2 | 2.3 | 2.1–16.3 |  < 0.001 |
Medications prior to extubation | ||||||||||||||
Dose of opioids within 24 h (mg) | 10 | 10 | 0–146 | 10 | 15 | 0–90 | 0.077 | 10 | 10 | 0–146 | 10 | 10 | 0–90 | 0.913 |
Dose of BZDs within 24 h (mg) | 1.8 | 5 | 0–382.50 | 5 | 13.48 | 0–684.50 | 0.050 | 8 | 7 | 0–684.50 | 5 | 10 | 0–348.20 | 0.823 |
Dose of propofol within 24 h (mg) | 0 | 0 | 0–4400 | 0 | 0 | 0–680 | 0.899 | 0 | 0 | 0–4400 | 0 | 16.67 | 0–680 | 0.464 |
APACHE II score | ||||||||||||||
At ICU admission | 26 | 10 | 6–41 | 24.5 | 11.25 | 6–43 | 0.723 | 25 | 10 | 6–41 | 23 | 11 | 6–40 | 0.283 |
At extubation | 32 | 10.25 | 19–66 | 23 | 9.25 | 14–40 |  < 0.001 | 29 | 10 | 17–66 | 23 | 8 | 14–37 | 0.172 |