Table 4 Multivariate Cox regression analysis of factors associated with patient death within 1Â h and survival beyond 1Â day
Death within 1Â h | RC | HR (95% CI) | p value |
|---|---|---|---|
Intubation (days) | 0.010 | 1.01 (0.99–1.03) | 0.219 |
Pulse oximetry (SpO2) (%) | − 0.006 | 0.99 (0.98–1.01) | 0.468 |
PEEP (cmH2O) | 0.099 | 1.10 (0.98–1.24) | 0.099 |
Static pressure (cmH2O) | 0.035 | 1.04 (0.99–1.08) | 0.093 |
Total dose of opioids within 24 h (mg) | 0.000 | 1.00 (0.99–1.01) | 0.981 |
Total dose of BZDs within 24 h (mg) | 0.001 | 1.00 (1.00–1.01) | 0.519 |
Education (elementary school or uneducated vs. more than high school) | − 0.432 | 0.65 (0.39–1.08) | 0.095 |
Cerebrovascular disease (yes vs. no) | 0.291 | 1.34 (0.85–1.58) | 0.356 |
Spontaneous breathing trail in 24 h (no vs. yes) | 2.448 | 11.57 (4.30–31.15) |  < 0.001 |
Minute ventilation 12(L/min (≥ 12 vs. < 12) | 1.488 | 4.43 (2.30–8.52) |  < 0.001 |
Inotropic agents use in 12 h (yes vs. no) | 0.393 | 1.48 (0.85–2.59) | 0.167 |
APACHE II score 25 (≥ 25 vs. < 25) | 2.681 | 14.60 (3.29–64.78) |  < 0.001 |
Survival beyond 1Â day | |||
 Intubation (days) | 0.004 | 1.00 (0.99–1.02) | 0.557 |
 PEEP (cmH2O) | 0.068 | 1.07 (0.97–1.18) | 0.170 |
 Static pressure (cmH2O) | 0.027 | 1.03 (1.00–1.06) | 0.092 |
 Minute ventilation (L/min) | 0.211 | 1.24 (1.16–1.32) |  < 0.001 |
 APACH II score at extubation | 0.007 | 1.01 (0.98–1.04) | 0.638 |
 DNR signed before family meeting (yes vs. no) | − 0.012 | 0.99 (0.76–1.29) | 0.928 |
 Pulse oximetry (SpO2 ≥ 96% vs. SpO2 < 96%) | 0.264 | 1.30 (1.05–1.61) | 0.015 |
 Spontaneous breathing trail in 24 h (yes vs. no) | 1.934 | 6.92 (3.60–13.29) |  < 0.001 |
 Inotropic agents use in 12 h (no vs. yes) | 0.227 | 1.26 (0.76–2.06) | 0.371 |