Fig. 2

A Rate of patients with Fib4 ≥ 2.67 (I) or ≥ 1.3 (II) by each status of ALT and AST abnormalities. Blue, orange, and red line presents ‘with normal limit (WNL),’ ‘ALT ≥ 40 (IU/l) or AST ≥ 40 (IU/l),’ and ‘ALT ≥ 40 (IU/l) and AST ≥ 40 (IU/l),’ respectively. B Rate of patients with Fib4 ≥ 2.67 (I) or ≥ 1.3 (II) by each status of smoking and that with Fib4 ≥ 2.67 (III) or ≥ 1.3 (IV) by each current status of DM (diabetes mellitus). In (I) and (II), blue, orange, gray, yellow, or dark blue line presents ‘none of smoking habit,’ ‘ < 20 pack-year,’ ‘20–29 pack-year,’ ‘30–39 pack-year,’ and ≥ ‘40 pack-year,’ respectively. In (III) and (IV), blue or orange line presents ‘no present history of DM’ or ‘present history of DM,’ respectively. C Rate of patients with Fib4 ≥ 2.67 (I) or ≥ 1.3 (II) by each status of alcohol drinking and that with Fib4 ≥ 2.67 (III) or ≥ 1.3 (IV) by each status of GGT. In (I) and (II), blue, orange, gray, or red line presents ‘no habit of alcohol drinking,’ ‘ < 20 g (ethanol)/day,’ ‘20 ≤ habit of alcohol drinking < 40,’ or ‘habit of alcohol drinking ≥ 40 g,’ respectively. In III) and IV), blue, orange, gray, or red line presents ‘GGT < 40 (U/l),’ ‘40 ≤ GGT < 70,’ ‘70 ≤ GGT < 200,’ or ‘GGT ≥ 200,’ respectively. D Rate of patients with Fib4 ≥ 2.67 (I) or ≥ 1.3 (II) by each status of BMI and that with Fib4 ≥ 2.67 (III) or ≥ 1.3 (IV) by each status of fatty liver. In (I) and (II), blue, green, yellow, or red line presents ‘BMI < 18.5 (kg/m²),’ ‘18.5 ≤ BMI < 25,’ ‘25 ≤ BMI < 30,’ or ‘ BMI ≥ 30,’ respectively. In (III) and (IV), blue or orange line presents ‘none of fatty liver’ or ‘present of fatty liver,’ respectively. E Rate of patients with Fib4 ≥ 2.67 (I) or ≥ 1.3 (II) by each status of HDL, and that with Fib4 ≥ 2.67 (III) or ≥ 1.3 (IV) by each status of LDL. In (I) and (II), blue, orange or red line presents ‘HDL < 40 (mg/dl),’ ‘40 ≤ HDL < 70,’ or ‘HDL ≥ 70,’ respectively. In (III) and (IV), red, orange or blue line presents ‘LDL < 120 (mg/dl),’ ‘120 ≤ LDL < 160,’ or ‘LDL ≥ 160,’ respectively