Fig. 3

Accumulating rate of Fib4 ≥ 2.67 by Cox analysis. A Accumulating rate of Fib4 ≥ 2.67 by each status of alcohol drinking (I) and GGT (II) at baseline (FY2000), FY2010, and FY2019). In (I), blue, green, purple, or orange line presents ‘no habit of alcohol drinking, ‘ < 20 g (ethanol)/day,’ ‘20–39 g,’ or ‘ ≥ 40 g,’ respectively. In (II), blue, green, purple, or orange line presents ‘GGT < 40 (IU/l),’ ‘40 ≤ GGT < 70,’ ‘70 ≤ GGT < 200,’ or ‘GGT ≥ 200,’ respectively. B Accumulating rate of Fib4 ≥ 2.67 by each status of BMI (I) and delta-BMI (II) at baseline (FY2000), FY2010, and FY2019). In (I), blue, green, purple, or orange line presents ‘BMI < 18.5 (kg/m²),’ ‘18.5 ≤ BMI < 25,’ ‘25 ≤ BMI < 30,’ or ‘ BMI ≥ 30,’ respectively. In (II), blue, green, or purple line presents ‘ delta-BMI < − 1 (kg/m²),’ ‘ − 1 ≤ delta-BMI <  + 2,’ or ‘ BMI ≥  + 2,’ respectively. C Accumulating rate of Fib4 ≥ 2.67 by each status of HDL (I) and LDL (II) at baseline (FY2000), FY2010, and FY2019). In (I), blue, purple, or green line presents ‘ HDL < 40 (mg/dl),’ ‘ 40 ≤ HDL < 70,’ or ‘ HDL ≥ 70,’ respectively. In (II), green, purple, or blue line presents ‘ LDL < 120 (mg/dl),’ ‘ 120 ≤ LDL < 160,’ or ‘ LDL ≥ 160,’ respectively