Survivors (N = 172) | Non-survivors (N = 40) | p-valuea | |
---|---|---|---|
Preoperative characteristics | |||
Male sex | 128 (74) | 27 (68) | 0.429 |
Age (years) | 55 ± 11 | 57 ± 11 | 0.140 |
BMI (kg/m2) | 25.6 ± 4.5 | 25.8 ± 5.1 | 0.861 |
Smoker | 41 (24) | 8 (20) | 0.681 |
Diabetes | 34 (20) | 14 (35) | 0.058 |
Arterial hypertension | 106 (62) | 21 (53) | 0.286 |
Pulmonary hypertension | 14 (8) | 5 (13) | 0.368 |
Donor–recipient sex mismatch | 45 (26) | 14 (35) | 0.327 |
Prior cardiothoracic surgery | 108 (63) | 29 (73) | 0.276 |
LVAD | 86 (50) | 25 (63) | 0.164 |
Preoperative ECMO | 5 (3) | 3 (8) | 0.175 |
Preoperative mechanical ventilation | 7 (4) | 3 (8) | 0.405 |
Preoperative dialysis | 7 (4) | 4 (10) | 0.127 |
Serum creatinine (mg/dl) | 1.4 ± 1.0 | 1.3 ± 0.5 | 0.649 |
Creatinine clearance (ml/min) | 65 ± 24 | 64 ± 31 | 0.793 |
Bilirubin (mg/dl) | 0.8 ± 0.9 | 1.2 ± 1.2 | 0.080 |
IMPACT score | 8 ± 5 | 10 ± 5 | 0.003 |
Donor characteristics | |||
Male sex | 99 (58) | 19 (48) | 0.290 |
Age (years) | 41 ± 12 | 50 ± 10 | < 0.0001 |
BMI (kg/m2) | 26 ± 5 | 25 ± 4 | 0.365 |
Smoker | 93 (54) | 17 (43) | 0.220 |
Arterial hypertension | 40 (23) | 16 (40) | 0.045 |
Diabetes | 11 (6) | 3 (8) | 0.731 |
Cardiopulmonary resuscitation | 55 (32) | 8 (20) | 0.179 |
Intraoperative characteristics (min) | |||
Duration of surgery | 424 ± 105 | 484 ± 144 | 0.017 |
Duration of CPB | 250 ± 64 | 301 ± 99 | 0.003 |
Total ischemia time | 212 ± 49 | 228 ± 52 | 0.070 |
Reperfusion time | 126 ± 45 | 151 ± 69 | 0.044 |
Postoperative characteristics | |||
ECMO | 38 (22) | 23 (58) | < 0.0001 |
Renal replacement therapy | 87 (53) | 31 (80) | 0.003 |
Neurological complication | 20 (12) | 17 (43) | < 0.0001 |
Days in ICU | 23 ± 22 | 30 ± 38 | 0.116 |
Duration of mechanical ventilation (hours) | 119 ± 168 | 268 ± 236 | 0.001 |