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Table 1 Characteristics of survivors and non-survivors after HTX

From: Postoperative high-sensitivity troponin T predicts 1-year mortality and days alive and out of hospital after orthotopic heart transplantation

 

Survivors (N = 172)

Non-survivors (N = 40)

p-valuea

Preoperative characteristics

 Male sex

128 (74)

27 (68)

0.429

 Age (years)

55 ± 11

57 ± 11

0.140

 BMI (kg/m2)

25.6 ± 4.5

25.8 ± 5.1

0.861

 Smoker

41 (24)

8 (20)

0.681

 Diabetes

34 (20)

14 (35)

0.058

 Arterial hypertension

106 (62)

21 (53)

0.286

 Pulmonary hypertension

14 (8)

5 (13)

0.368

 Donor–recipient sex mismatch

45 (26)

14 (35)

0.327

 Prior cardiothoracic surgery

108 (63)

29 (73)

0.276

 LVAD

86 (50)

25 (63)

0.164

 Preoperative ECMO

5 (3)

3 (8)

0.175

 Preoperative mechanical ventilation

7 (4)

3 (8)

0.405

 Preoperative dialysis

7 (4)

4 (10)

0.127

 Serum creatinine (mg/dl)

1.4 ± 1.0

1.3 ± 0.5

0.649

 Creatinine clearance (ml/min)

65 ± 24

64 ± 31

0.793

 Bilirubin (mg/dl)

0.8 ± 0.9

1.2 ± 1.2

0.080

 IMPACT score

8 ± 5

10 ± 5

0.003

Donor characteristics

 Male sex

99 (58)

19 (48)

0.290

 Age (years)

41 ± 12

50 ± 10

 < 0.0001

 BMI (kg/m2)

26 ± 5

25 ± 4

0.365

 Smoker

93 (54)

17 (43)

0.220

 Arterial hypertension

40 (23)

16 (40)

0.045

 Diabetes

11 (6)

3 (8)

0.731

 Cardiopulmonary resuscitation

55 (32)

8 (20)

0.179

Intraoperative characteristics (min)

 Duration of surgery

424 ± 105

484 ± 144

0.017

 Duration of CPB

250 ± 64

301 ± 99

0.003

 Total ischemia time

212 ± 49

228 ± 52

0.070

 Reperfusion time

126 ± 45

151 ± 69

0.044

Postoperative characteristics

 ECMO

38 (22)

23 (58)

 < 0.0001

 Renal replacement therapy

87 (53)

31 (80)

0.003

 Neurological complication

20 (12)

17 (43)

 < 0.0001

 Days in ICU

23 ± 22

30 ± 38

0.116

 Duration of mechanical ventilation (hours)

119 ± 168

268 ± 236

0.001

  1. BMI body mass index, CPB cardiopulmonary bypass, ECMO extracorporeal membrane oxygenation, IMPACT risk index for mortality prediction after cardiac transplantation, ICU intensive care unit, LVAD left ventricular assist device