Table 2 Patient presentations by group on days 8 and 15
Treatment group (D8) n = 20 | Control group (D8) n = 20 | p-valuea | |||
|---|---|---|---|---|---|
Median (IQR) | Mean ± SD | Median (IQR) | Mean ± SD | ||
Body weight (kg) | 0.0(0.0 to 0.0) | 0.25 ± 0.64 | 0.0(0.0 to 0.0) | 0.28 ± 1.14 | 0.433 |
SBP (mmHg) | 1.00(− 10.0 to 7.8) | 0.60 ± 13.11 | 1.0(− 7.8 to 7.3) | 2.30 ± 11.98 | 0.745 |
DBP (mmHg) | 0.00(− 5.8 to 3.5) | 0.40 ± 8.31 | 0.0(− 7.5 to 6.0) | 1.80 ± 14.62 | 0.903 |
WBC (/μl) | − 960(− 2622.5 to − 55.0) | − 1392 ± 1505 | − 1120(− 2642.5 to − 177.5) | − 1368.5 ± 1774.3 | 0.903 |
RBC (104/μl) | 6.0(0.0–20.3) | 10.30 ± 19.02 | − 4.0(− 11.3 to 9.3) | − 0.25 ± 18.31 | 0.042* |
Hb (g/dl) | 0.0(− 0.1 to 0.7) | 0.31 ± 0.67 | − 0.1(− 0.4 to 0.4) | − 0.02 ± 0.52 | 0.139 |
Hct (%) | 0.5(− 0.2 to 2.0) | 0.88 ± 1.68 | − 0.2(− 1.6 to 1.0) | −0.26 ± 1.78 | 0.047* |
MCV (fl) | 0.0(− 0.4 to 0.5) | 0.01 ± 0.64 | − 0.3(− 1.0 to 0.3) | − 0.42 ± 0.81 | 0.143 |
MCH (Pg) | 0.0(− 0.4 to 0.3) | − 0.02 ± 0.44 | − 0.1(− 0.5 to 0.4) | − 0.01 ± 0.46 | 0.968 |
MCHC (g/dl) | 0.0(− 0.4 to 0.4) | − 0.03 ± 0.44 | 0.1(− 0.2 to 0.6) | 0.13 ± 0.53 | 0.408 |
Platelet (/μl) | 11.5 K(− 6.5 K to 27.5 K) | 10750 ± 26098.7 | 8 K(− 6.5 K to 25.3 K) | − 900 ± 47901.1 | 0.787 |
GPT (IU/l) | 0.0(− 3.8 to 7.3) | 1.15 ± 7.68 | 4.5(− 1.8 to 26.8) | 11.40 ± 18.36 | 0.107 |
Creatine (mg/dl) | 0.1(0.0 to 0.2) | 0.07 ± 0.12 | 0.02(0.0 to 0.1) | 0.06 ± 0.12 | 0.494 |
CRP (mg/dl) | − 0.2(− 0.9 to 0.0) | − 0.55 ± 1.11 | − 0.4(− 1 to − 0.1) | − 1.00 ± 1.96 | 0.336 |
Uric acid (mg/dl) | − 1.9(− 3.7 to 0.0) | − 1.77 ± 2.037 | 0.8(− 0.1 to 2.2) | 1.24 ± 2.084 | < 0.001*** |
VAS | − 5.5(− 8.0 to − 3.0) | − 5.2 ± 3.09 | − 3.5(− 5.9 to − 2.0) | − 3.63 ± 2.38 | 0.080 |
Treatment group (D15) n = 20 | Control group (D15) n = 20 | p-valuea | |||
|---|---|---|---|---|---|
Median (IQR) | Mean ± SD | Median (IQR) | Mean ± SD | ||
Body weight (kg) | 0.0(0.0 to 0.0) | 0.20 ± 0.70 | 0.0(0.0 to 0.0) | 0.06 ± 0.34 | 0.638 |
SBP (mmHg) | 0.5(− 6.8 to 7.8) | − 0.25 ± 9.78 | 2.5(− 13.3 to 5.5) | − 1.30 ± 13.09 | 0.892 |
DBP (mmHg) | − 0.5(− 6.0 to 5.3) | − 1.15 ± 11.39 | 0.0(− 12.3 to 5.5) | − 1.85 ± 11.53 | 0.946 |
WBC (μl) | − 1115(− 2805 to 0.0) | − 1394 ± 1820.5 | − 1200(− 2682.5 to − 225.0) | − 1266.5 ± 2261.4 | 0.892 |
RBC (104/μl) | 2.0(− 17.8 to 18.5) | 1.45 ± 19.69 | 4.0(− 10.0 to 11.5) | 2.20 ± 18.02 | 0.946 |
Hb (g/dl) | 0.1(− 0.6 to 0.5) | 0.01 ± 0.57 | 0.1(− 2.0 to 0.4) | − 0.02 ± 0.52 | 0.870 |
Hct (%) | 0.0(− 1.7 to 1.5) | 0.05 ± 1.56 | 0.1(− 1.3 to 1.2) | − 0.07 ± 1.78 | 0.989 |
MCV (fl) | − 0.1(− 0.4 to 0.1) | – 0.23 ± 0.50 | − 0.8(− 1.0 to 0.4) | − 0.49 ± 1.06 | 0.316 |
MCH (Pg) | − 0.1(− 0.4 to 0.3) | − 0.11 ± 0.44 | –0 .1(− 0.4 to 0.1) | − 0.15 ± 045 | 0.786 |
MCHC (g/dl) | 0.0(–0 .3 to 0.4) | − 0.02 ± 0.44 | − 0.1(− 0.3 to 0.3) | − 0.01 ± 0.59 | 0.645 |
Platelet (μl) | 8 K(− 22.3 K–27.8 K) | 5050 ± 28943.6 | 2 K(− 8.3 K–21.5 K) | − 16800 ± 76110.4 | 0.579 |
GPT (IU/l) | 0.0(− 2.0 to 4.8) | 1.20 ± 5.90 | 7.0(− 0.8 to 15.5) | 10.50 ± 17.77 | 0.029* |
Creatine (mg/dl) | 0.0(0.0 to 0.1) | 0.02 ± 0.14 | 0.0(− 0.1 to 0.1) | 0.04 ± 0.11 | 0.741 |
CRP (mg/dl) | − 0.3(− 1.1 to 0.0) | − 0.89 ± 1.53 | − 0.5(− 1.4 to − 0.2) | − 01.12 ± 2.02 | 0.213 |
Uric acid (mg/dl) | − 1.7(− 2.9 to 0.0) | − 1.36 ± 1.82 | 0.3(− 0.2 to 1.0) | 0.81 ± 2.09 | 0.002** |
VAS | − 5.5(− 8.0 to − 3.1) | − 5.68 ± 3.01 | − 4.8(− 7.0 to − 2.0) | − 4.37 ± 2.86 | 0.161 |