Fig. 1
From: A novel stop-gain pathogenic variant in the KCNQ1 gene causing long QT syndrome 1
The image presents the pedigree of the family with long QT (LQT) syndromes, as well as the results of the electrocardiogram (ECG) and sequencing chromatograms of the mutated nucleotide in the KCNQ1 gene. A The pedigree of the family with LQT syndromes is presented herein. The proband is indicated with the arrow. B The Sanger sequencing results of the KCNQ1 gene in the patient and his family members are shown here. The patients carried a heterozygous nonsense variant: c.G968A. C The image demonstrates the poor region of the Kv11.1 schematic structure with the W323X variant. D This region includes amino acids conserved among humans, mice, rats, rabbits, and horses