Table 1 The classification and staging of the RIFLE, AKIN and KDIGO criteria
Workgroup | RIFLE | AKIN | KDIGO |
|---|---|---|---|
Acute dialysis quality initiative group | Acute kidney injury Network | Kidney disease improving Global outcome | |
Criteria | SCr, UO, GFR, clinical outcome | SCr, UO | SCr, UO, GFR |
Staging | Risk SCr increased by 1.5 ×  UO < 0.5 mL/kg/h for 6 h eGFR decreased by > 25% within 7 d | Stage 1 SCr increased > 0.3 mg/dL SCr increased by 1.5 × to 2.0 ×  UO < 0.5 mL/kg/h for > 6 h | Stage 1 SCr increased ≥ 0.3 mg/dL within 48 h SCr increased by 1.5 × to 1.9 × , which is known or presumed to have occurred within prior 7 d UO < 0.5 mL/kg/h for 6–12 h |
|  | Injury SCr increased by 2.0 ×  UO < 0.5 mL/kg/h for 12 h eGFR decreased by > 50% | Stage 2 SCr increased by > 2.0 × to 3.0 ×  UO < 0.5 mL/kg/h for > 12 h | Stage 2 SCr increased by 2.0 × to 2.9 ×  UO < 0.5 mL/kg/h for 12 h |
|  | Failure SCr increased by 3.0 ×  SCr ≥ 4 mg/dL with acute rise ≥ 0.5 mg/dL UO < 0.3 mL/kg/h for 24 h Anuria for 12 h eGFR decreased by > 75% | Stage 3 SCr increased by > 3.0 ×  SCr ≥ 4 mg/dL with acute rise ≥ 0.5 mg/dL UO < 0.3 mL/kg/h for 24 h Anuria for 12 h | Stage 3 SCr increased by ≥ 3.0 ×  SCr ≥ 4 mg/dL Initiation of RRT UO < 0.3 mL/kg/h for 24 h Anuria for 12 h eGFR < 35 mL/min/1.73 m2(in patients < 18 yr) |
|  | Loss Complete loss of kidney function > 4 wk |  |  |
|  | End-stage kidney disease Complete loss of kidney function > 3 mo |  |  |