Respiratory viruses and postoperative hemodynamics in patients with unrestrictive congenital cardiac communications: a prospective cohort study

Table 5 Inflammatory markers and postoperative elevation of pulmonary arterial pressure: univariate and bivariate analyses

	Coefficient	Odds ratio^a	95% CI		p value
	Coefficient	Odds ratio^a	Lower limit	Upper limit	p value
IL-1RA	0.583	1.79	1.02	3.14	0.041
IL-6	0.708	2.03	1.10	3.76	0.024
IL-10	0.599	1.82	1.00	3.31	0.049
IL-17E	0.558	1.75	0.98	3.13	0.061
MCP-1	0.468	1.60	0.92	2.78	0.096
MIF	0.583	1.79	1.02	3.14	0.041
MIP-1α/β	0.558	1.75	0.98	3.13	0.061
TNF-α	0.522	1.69	0.94	3.02	0.079
IL-18	0.599	1.82	1.00	3.31	0.049
IL-21	0.818	2.27	1.23	4.19	0.009
IL-1RA	0.711	2.04 (14% increase)	1.09	3.81	0.026
Presence of respiratory viral genomes in the trachea	1.475	4.37	1.08	17.63	0.038
MIF	0.849	2.34 (31% increase)	1.15	4.74	0.019
Presence of respiratory viral genomes in the trachea	1.432	4.19	1.03	16.96	0.045
MCP-1	0.780	2.18 (36% increase)	1.07	4.43	0.031
Presence of respiratory viral genomes in the trachea	1.843	6.32	1.30	30.71	0.022

Cytokine concentrations were measured 4 h after cardiopulmonary bypass termination and analyzed as quartiles
Shown in bivariate analysis are the proteins with a > 10% increase in odds ratio relative to univariate analysis
The first step consisted of selecting cytokines with a p value < 0.10
^aAssociated with early postoperative pulmonary/systemic mean arterial pressure ratio > 0.40 (mean of first 4 values, readings at 2-h intervals). Results were obtained using logistic regression analysis

ISSN: 2047-783X