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Table 1 Demographic properties of the study population

From: Are bacterial coinfections really rare in COVID-19 intensive care units?

Variable

Coinfection (−)

(n = 135)

Coinfection (+)

(n = 216)

p-value

Age&

63.6 ± 14.4

66.0 ± 14.6

0.148

 Female, gender, n (%)

50 (37)

84 (39)

0.728

Comorbid diseases

   

 Diabetes mellitus n (%)

59 (39)

94 (61)

0.973

 Hypertension n (%)

68 (50)

118 (55)

0.437

 Chronic obstructive pulmonary disease n (%)

20 (15)

31 (14)

0.905

  Coronary heart disease n (%)

38 (28)

57 (26)

0.718

  Solid tm n (%)

7(5)

20 (9)

0.163

  Hematological malignancies n (%)

2 (2)

7 (3)

0.310

  Immunosuppression n (%)

4 (3)

4 (2)

0.497

  Obesity n (%)

13 (10)

23 (11)

0.760

  Chronic liver disease n (%)

2 (2)

5 (2)

0.587

  Chronic kidney disease n (%)

10 (7)

22 (10)

0.379

  Thyroid dysfunction n (%)

4 (3)

9 (4)

0.561

  Dementia- Alzheimer n (%)

10 (7)

26 (12)

0.164

  Postoperative status n (%)

3 (2)

12 (6)

0.133

  SOFA* 0 day

7 (4–8)

7 (4–9)

0.092

  SOFA* 3 day

7 (4–9)

8 (6–11)

0.001

  MV n (%)

85 (63)

192 (89)

 < 0.001

  CPAP, n (%)

19 (14)

22 (10)

0.270

  HFNC, n (%)

25 (19)

28 (13)

0.157

  Reservoir O2 mask, n (%)

44 (33)

59 (27)

0.291

  Simple O2 mask, n (%)

48 (36)

53 (25)

0.027

  Nasal cannula, n (%)

7 (5)

9 (4)

0.656

  ARDS at arrival, n (%)

114 (85)

186 (87)

0.402

  Community-acquired infection n (%)

86 (40)

  Nosocomial infection n (%)

130 (60)

  Outcome Death 7 Day

27 (20)

40 (19)

0.731

  Outcome 21 day

63 (47)

134 (62)

0.005

  Hospitalization day*

13 (9–19)

16 (10–24)

0.014

  ICU hospitalization day*

6 (4–11)

10 (6–14)

0.000

  Mortality, n (%)

63 (47)

135(63)

0.004

  1. SOFA Sequential Organ Failure Assessment, MV mechanical ventilation, CPAP continuous positive airway pressure, HFCN high-flow nasal oxygen, O2 oxygen, ARDS acute respiratory distress syndrome, ICU intensive care unit
  2. Continuous variables are presented as mean ± standard deviation, and comparison was made using the student t-test at p < 0.05
  3. Categorical variables are shown as number of subjects, with percentage of total number, and comparison was made using the Chi-square test at p < 0.05
  4. *These variables are presented as median (interquartile range). Comparison was made using the Mann–Whitney U test at p < 0.05