From: Are bacterial coinfections really rare in COVID-19 intensive care units?
Variable | Coinfection (−) (n = 135) | Coinfection (+) (n = 216) | p-value |
---|---|---|---|
Age& | 63.6 ± 14.4 | 66.0 ± 14.6 | 0.148 |
Female, gender, n (%) | 50 (37) | 84 (39) | 0.728 |
Comorbid diseases | |||
Diabetes mellitus n (%) | 59 (39) | 94 (61) | 0.973 |
Hypertension n (%) | 68 (50) | 118 (55) | 0.437 |
Chronic obstructive pulmonary disease n (%) | 20 (15) | 31 (14) | 0.905 |
Coronary heart disease n (%) | 38 (28) | 57 (26) | 0.718 |
Solid tm n (%) | 7(5) | 20 (9) | 0.163 |
Hematological malignancies n (%) | 2 (2) | 7 (3) | 0.310 |
Immunosuppression n (%) | 4 (3) | 4 (2) | 0.497 |
Obesity n (%) | 13 (10) | 23 (11) | 0.760 |
Chronic liver disease n (%) | 2 (2) | 5 (2) | 0.587 |
Chronic kidney disease n (%) | 10 (7) | 22 (10) | 0.379 |
Thyroid dysfunction n (%) | 4 (3) | 9 (4) | 0.561 |
Dementia- Alzheimer n (%) | 10 (7) | 26 (12) | 0.164 |
Postoperative status n (%) | 3 (2) | 12 (6) | 0.133 |
SOFA* 0 day | 7 (4–8) | 7 (4–9) | 0.092 |
SOFA* 3 day | 7 (4–9) | 8 (6–11) | 0.001 |
MV n (%) | 85 (63) | 192 (89) | < 0.001 |
CPAP, n (%) | 19 (14) | 22 (10) | 0.270 |
HFNC, n (%) | 25 (19) | 28 (13) | 0.157 |
Reservoir O2 mask, n (%) | 44 (33) | 59 (27) | 0.291 |
Simple O2 mask, n (%) | 48 (36) | 53 (25) | 0.027 |
Nasal cannula, n (%) | 7 (5) | 9 (4) | 0.656 |
ARDS at arrival, n (%) | 114 (85) | 186 (87) | 0.402 |
Community-acquired infection n (%) | – | 86 (40) | – |
Nosocomial infection n (%) | – | 130 (60) | – |
Outcome Death 7 Day | 27 (20) | 40 (19) | 0.731 |
Outcome 21 day | 63 (47) | 134 (62) | 0.005 |
Hospitalization day* | 13 (9–19) | 16 (10–24) | 0.014 |
ICU hospitalization day* | 6 (4–11) | 10 (6–14) | 0.000 |
Mortality, n (%) | 63 (47) | 135(63) | 0.004 |