Table 1 Characteristics of included randomized control trial studies
Authors | Years | Country | Dose oral indevotional | Dose vaginal interventional | Hours of intervention | Total sample | Sample oral indevotional | Sample Vaginal Interventional | Age |
|---|---|---|---|---|---|---|---|---|---|
Cheng et al. | 2008 | China | 25 mcg | 25 mcg | 4 | 207 | 101 | 106 | 28.3 |
Rezaie et al. | 2016 | Iran | 100 ug | 25 ug | 4 | 120 | 60 | 60 | 27.7 |
Souza et al. | 2013 | Brazil | 20 ug | 25 ug | 6 | 200 | 100 | 100 | 23 |
Sarella et al. | 2021 | India | 20 ug | 25 ug | 2 | 80 | 40 | 40 | 22.5 |
Kaur et al. | 2015 | India | 25 ug | 25 ug | 4 | 100 | 50 | 50 | 25.6 |
Mehta et al. | 2020 | India | 25 ug | 25 ug | 4 | 100 | 50 | 50 | 26 |
How et al. | 2001 | USA | 25 ug | 25 ug | 4 | 219 | 109 | 110 | 23.4 |
Bagariya et al. | 2020 | India | 25 ug | 25 ug | 4 | 196 | 98 | 98 | NR |
Rezaie et al. | 2016 | Iran | 50 ug | 25 ug | 4 | 120 | 60 | 60 | 28.4 |
Wing et al. | 1999 | USA | 50 ug | 25 ug | 4 | 220 | 110 | 110 | NR |
Komala et al. | 2013 | India | 50 ug | 25 ug | 4 to 6 | 200 | 100 | 100 | NR |
Rahman et al. | 2013 | India | 50 ug | 25 ug | 4 | 220 | 110 | 110 | 27.2 |
Colon et al. | 2005 | USA | 50 ug | 25 ug | 4 | 204 | 93 | 111 | 28.1 |
Zvandasara et al. | 1999 | Zimbabwe | 50 ug | 25 ug | 1 | 134 | 69 | 65 | 23 |
Paisarntantiwong et al. | 2005 | Thailand | 50 ug | 25 ug | NR | 146 | 73 | 73 | 25.6 |
Galidevara et al. | 2018 | India | 50 ug | 25 ug | 4 | 163 | 80 | 83 | 24.4 |
Sheela et al. | 2007 | India | 50 ug | 25 ug | 6 | 100 | 50 | 50 | 24 |
Deshmukh et al. | 2013 | India | 50 mcg | 50 mcg | 6 | 200 | 100 | 100 | 26.4 |
Nopdonrattakoon et al. | 2003 | Thailand | 50 mg | 50 mg | 4 | 106 | 53 | 53 | 24.9 |
Sheikher et al. | 2009 | India | 50 ug | 50 ug | 4 | 60 | 30 | 30 | NR |
Roux et al. | 2002 | South Africa | 50 ug | 50 ug | 6 | 240 | 120 | 120 | 28.1 |
Kwon et al. | 2001 | Canada | 50 ug | 50 ug | 6 | 160 | 78 | 82 | 27.2 |
Bennett et al. | 1998 | Canada | 50 ug | 50 ug | 4 | 206 | 104 | 102 | 28.7 |
Shetty et al. | 2001 | UK | 50 ug | 50 ug | 4 | 245 | 122 | 123 | 28 |
Promila et al. | 2011 | India | 50 ug | 50 ug | 4 | 103 | 51 | 52 | 26 |
Elhassan et al. | 2007 | Sudan | 50 ug | 50 ug | NR | 100 | 50 | 50 | NR |
Ezechukwu et al. | 2015 | Nigeria | 50 ug | 50 ug | 24 | 140 | 70 | 70 | 27.2 |
Fisher et al. | 2001 | Canada | 50 ug | 50 ug | 6 | 126 | 62 | 64 | 27 |
Young et al. | 2020 | Canada | 50 ug | 50 ug | 4 | 339 | 167 | 172 | 29.1 |
Ambika et al. | 2017 | India | 50 ug | 50 ug | 6 | 200 | 100 | 100 | 20 |
Mehrotra et al. | 2010 | India | 50 ug | 50 ug | 4 | 128 | 60 | 68 | 26.24 |
Adam et al. | 2005 | Sudan | 50 ug | 50 ug | 6 | 80 | 40 | 40 | NR |