Table 4 Clinical trials based on MSCs transplantation in IBD patients
Disease | Phase | Source | Administration route (dose) | Participant Number | Study location | Status | NCT number |
|---|---|---|---|---|---|---|---|
CD | 1 | Allogeneic UC | Intravenous | 15 | Antigua and Barbuda | Recruiting | NCT05003947 |
UC | 1/2 | Allogeneic WJ | Intravenous | 20 | Jordan | Unknown | NCT03299413 |
CD | 2 | Allogeneic BM | Intravenous | 10 | USA | Completed | NCT00294112 |
CD | 1 | Allogeneic BM | NA | 10 | Iran | Unknown | NCT01874015 |
CD | 1/2 | Autologous AT | Intracolonic | 15 | Spain | Completed | NCT01157650 |
UC | 1/2 | Allogeneic AT | Intracolonic | 8 | Spain | Unknown | NCT01914887 |
CD | 1/2 | Allogeneic UC | Intravenous | 82 | China | Completed | NCT02445547 |
CD | 1/2 | Allogeneic BM | Intravenous | 13 | Belgium | Terminated | NCT01540292 |
CD | 1 | Allogeneic BM-EVs | Intravenous | 10 | USA | Not yet recruiting | NCT05130983 |
UC | 1/2 | Allogeneic UC | Intravenous | 50 | China | Unknown | NCT01221428 |
CD | 1/2 | Allogeneic BM | Intracolonic | 21 | Netherlands | Completed | NCT01144962 |
CD | 1/2 | Allogeneic BM | Intracolonic | 40 | USA | Recruiting | NCT04519684 |
CD | 1/2 | Allogeneic BM | Intracolonic | 40 | USA | Recruiting | NCT04519697 |
UC | 1/2 | Allogeneic BM | Intracolonic | 20 | USA | Not yet recruiting | NCT05075811 |
CD | 1 | Allogeneic UC | Intracolonic | 7 | Malaysia | Not yet recruiting | NCT05039411 |
CD | 1 | Allogeneic BM | Intracolonic | 10 | USA | Recruiting | NCT04791878 |
CD | 3 | Allogeneic AT | Intracolonic | 278 | International | Completed | NCT01541579 |
CD | 1/2 | Allogeneic BM | Intracolonic | 24 | USA | Recruiting | NCT04548583 |
UC | 1/2 | Allogeneic AT | Intracolonic | 50 | China | Recruiting | NCT03609905 |
CD | 3 | Allogeneic BM | Intravenous | 330 | International | Completed | NCT00482092 |
UC | 1/2 | Allogeneic UC | Intravenous | 30 | China | Unknown | NCT02442037 |
CD | 3 | Allogeneic BM | Intravenous | 98 | International | Completed | NCT00543374 |
UC | 1/2 | Allogeneic BM | Intracolonic | 24 | USA | Recruiting | NCT04543994 |
CD | 1 | Allogeneic UC | Intracolonic | 24 | China | Enrolling by invitation | NCT04939337 |
UC | 1 | Autologous AT | Intraarterial | 20 | USA | Recruiting | NCT04312113 |