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Table 2 Characteristics of included studies

From: Effects of low-level laser therapy on orthodontic miniscrew stability: a systematic review

Author and year

Age (years)

Sample size(M/F)

Design

Miniscrew dimension (diameter/length in mm)

Implanted sites

Evaluation method

Evaluation interval

Statistical analysis

Study conclusion

Abdullah Ekizer et al. (2016)

16.77 ± 1.4 (19–13.1)

20 (7/13)

Split-mouth RCT

1.6/8

Buccal region between the roots of maxillary second premolar and first molar

Resonance frequency analysis (RFA) Osstell ISQ device (Osstell, Gothenburg, Sweden)

Miniscrew placement (baseline), 1, 2 and 3 months

Paired samples t-test were used at P < 0.05 level

Photobiomodulation therapy had positive effect on stability of miniscrews during canine distalization

Osman A et al. (2017)

18 (14–32)

12 (6/6)

Split-mouth RCT

1.5/8

Buccal region between the roots of maxillary second premolar and first molar

Damping capacity assessment (DCA) Periotest device (Siemens AG, Bensheim, Germany)

Before and after loading 7, 14, 21, 30 and 60 days

Paired samples t-test were used at P < 0.05 level

LLLT can be suggested as a clinical adjuvant for improving clinical success with miniscrew treatment. However, more long-term studies incorporating more study subjects is deemed necessary to further validate the study results

AhmedMohamed Abohabib et al. (2018)

20.9 ± 3.4 (16–25)

14

Split-mouth RCT

1.5/8

Buccal region between the roots of maxillary second premolar and first molar

Resonance frequency analysis (RFA) Osstell device (Osstell, Gothenburg, Sweden)

0,1,2,3,4,6,8,10 weeks after mini-implant placement

Paired samples t-test was used at P < 0.05 level to compare two groups, Tukey’s post hoc test was used to study the changes of time in each group

Despite evidence of some significant differences in resonance frequency between mini-implants exposed to low-intensity laser light over a 10-week period there were no differences in mini-implant stability. LLLT cannot be recommended as a clinically useful adjunct to promoting mini-implant stability during canine retraction