Fig. 3

Cancer hallmarks and immune infiltration of the RNA methylation writers. A The genomic distribution of the RNA methylation writers. B PCA of the RNA methylation writers for distinguishing tumor and normal patients in TCGA-LIHC cohort. C The regulatory network of the RNA methylation writers based on the consensus analysis. D Spearman correlation analysis showed positive or negative correlation among RNA methylation writers in HCC. E Consensus clustering of RNA methylation writers in 5 cohorts. F Kaplan–Meier curves demonstrating the overall survival of Cluster_1 and Cluster_2. G GSVA enrichment analysis shows the correlation of the two clusters with biological pathways and cancer hallmarks. H The difference of immune cell infiltration in TME between Cluster_1 and Cluster_2. I The expression difference M0 macrophage and CD4 T cell between Cluster_1 and Cluster_2