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Table 2 Laboratory tests of non-frail and frail patients with diabetes

From: Association of metformin exposure with low risks of frailty and adverse outcomes in patients with diabetes

Variable

Non-frail (n = 340)

Frail (n = 82)

P value

FPG (mmol/L)

7.18 ± 2.36

7.16 ± 3.27

0.079

HbA1c (%)

7.37 ± 1.52

7.06 ± 1.33

0.067

Triglyceride (mmol/L)

1.79 ± 0.79

1.47 ± 0.70

0.379

Total cholesterol (mmol/L)

4.25 ± 1.15

4.04 ± 1.21

0.044

HDL (mmol/L)

1.12 ± 0.32

1.07 ± 0.30

0.214

LDL (mmol/L)

2.48 ± 0.90

2.39 ± 1.00

0.242

Creatinine (umol/L)

70.80 ± 40.76

94.89 ± 64.03

 < 0.001

BUN (mmol/L)

6.19 ± 2.19

8.92 ± 4.96

 < 0.001

Prealbumin (mg/L)

248.31 ± 121.64

222.26 ± 65.25

0.062

Albumin (mg/L)

40.14 ± 3.88

37.29 ± 5.69

 < 0.001

Hemoglobin (g/L)

135.98 ± 17.41

124.27 ± 21.90

 < 0.001

CRP (mg/L)

2.13 (1.90, 4.00)

3.00 (2.00, 5.00)

0.222

D-Dimer (ug/mL)

0.29 (0.20, 0.45)

0.59 (0.37, 1.00)

 < 0.001

Fibrinogen (g/L)

3.38 ± 0.72

3.66 ± 0.98

0.016

NT-proBNP (pg/mL)

74.85 (39.75, 197.25)

348.5 (103.98, 781.75)

 < 0.001

Urine mALB/Cre

1.50 (0.30, 7.30)

7.00 (0.91, 28.50)

 < 0.001

  1. Data for continuous variables are presented as mean ± (standard deviation) or median (interquartile range)
  2. FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BUN, blood urea nitrogen; CRP, C-reactive protein; NT-proBNP, N-terminal pro-B-type natriuretic peptide; mALB/Cre, microalbuminuria/creatinine