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Table 6 Laboratory tests of non-metformin and metformin groups

From: Association of metformin exposure with low risks of frailty and adverse outcomes in patients with diabetes

Variable

Non-metformin (n = 177)

Metformin (n = 245)

P value

FPG (mmol/L)

6.73 ± 2.59

7.50 ± 2.49

0.002

HbA1c (%)

6.92 ± 1.23

7.59 ± 1.59

 < 0.001

Triglyceride (mmol/L)

1.49 ± 0.93

1.90 ± 1.99

0.005

Total cholesterol (mmol/L)

4.16 ± 1.16

4.25 ± 1.17

0.442

HDL (mmol/L)

1.14 ± 0.37

1.09 ± 0.26

0.086

LDL (mmol/L)

2.45 ± 0.94

2.47 ± 0.90

0.819

Creatinine (umol/L)

85.22 ± 65.82

68.45 ± 24.14

0.001

BUN (mmol/L)

7.41 ± 4.14

6.23 ± 1.98

 < 0.001

Prealbumin (mg/L)

225.72 ± 57.32

255.91 ± 139.28

0.007

Albumin (mg/L)

38.90 ± 4.87

40.08 ± 4.01

0.007

Hemoglobin (g/L)

130.98 ± 21.57

135.67 ± 16.51

0.016

CRP (mg/L)

2.34 (2.00, 4.58)

2.05 (1.84, 4.00)

0.823

D-Dimer (ug/mL)

0.41 (0.26, 0.70)

0.28 (0.19, 0.43)

0.001

Fibrinogen (g/L)

3.50 ± 0.85

3.39 ± 0.73

0.158

NT-proBNP (pg/mL)

188.00 (73.5, 495.25)

67.05 (37.00, 181.50)

0.007

Urine mALB/Cre

1.64 (0.44, 14.80)

1.85 (0.30, 10.03)

0.021

  1. Data for continuous variables are presented as mean ± (standard deviation) or median (interquartile range)
  2. FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BUN, blood urea nitrogen; CRP, C-reactive protein; NT-proBNP, N-terminal pro-B-type natriuretic peptide; mALB/Cre, microalbuminuria/creatinine