Variables | Young (n = 32) | Old (n = 32) | p value | |
---|---|---|---|---|
General information | Age (years), mean (SD) | 53.59 (5.71) | 76.06 (8.64) | < 0.001 |
Male, no (%) | 24 (75) | 24 (75) | 1.000 | |
Weight (Kg), mean (SD) | 76.39 (14.67) | 69.28 (9.98) | 0.027 | |
Height (cm), mean (SD) | 170.47 (8.15) | 167.53 (5.97) | 0.105 | |
BMI (Kg/m2), mean (SD) | 26.17 (4.01) | 24.63 (3.03) | 0.089 | |
Smoking, no (%) | 11 (34.4) | 8 (25.0) | 0.412 | |
Drinking, no (%) | 13 (40.6) | 6 (18.8) | 0.055 | |
Physical capacity | Gait speed (m/s), mean (SD) | 1.14 (0.38) | 0.84 (0.42) | 0.011 |
Grip strength (Kg), mean (SD) | 38.5 (8.7) | 28.5 (8.4) | < 0.001 | |
Blood pressure | SBP (mmHg), mean (SD) | 131.97 (16.89) | 136.53 (19.19) | 0.317 |
DBP (mmHg), mean (SD) | 80.06 (10.46) | 72.97 (12.70) | 0.018 | |
PP (mmHg), mean (SD) | 51.91 (13.66) | 63.56 (16.06) | 0.003 | |
Medical history | Hypertension, no (%) | 21 (65.6) | 24 (75) | 0.412 |
Coronary heart disease, no (%) | 4 (12.5) | 9 (28.1) | 0.120 | |
Chronic obstructive pulmonary disease, no (%) | 0 (0.0) | 1 (3.1) | 0.313 | |
Cerebravascular accident, no (%) | 3 (9.4) | 13 (40.6) | 0.004 | |
Type 2 diabetes mellitus, no (%) | 13 (40.6) | 13 (40.6) | 1.000 | |
Number of chronic diseases, mean (SD) | 2.91 (2.29) | 5.41 (3.11) | 0.001 | |
Number of drugs, mean (SD) | 3.03 (2.21) | 5.72 (3.07) | < 0.001 | |
Laboratory tests | Creatinine (µmol/L), mean (SD) | 66.50 (21.69) | 76.44 (27.27) | 0.112 |
CCr (mL/(min*1.73 m2)), mean (SD) | 119.17 (33.88) | 75.91 (29.25) | < 0.001 | |
Alanine aminotransferase (IU/L), mean (SD) | 24.53 (12.61) | 22.00 (12.55) | 0.424 | |
Aspartate aminotransferase (IU/L), mean (SD) | 23.65 (4.77) | 24.19 (8.01) | 0.746 | |
Albumin (g/L), mean (SD) | 41.35 (2.77) | 38.98 (3.73) | 0.007 | |
Hemoglobin (g/L), mean (SD) | 146.53 (13.70) | 133.69 (14.87) | 0.001 | |
Triglycerides (mmol/L), mean (SD) | 2.08 (1.10) | 1.53 (1.04) | 0.052 | |
Total cholesterol (mmol/L), mean (SD) | 4.51 (0.78) | 3.97 (0.86) | 0.015 | |
High-density lipoprotein (mmol/L), mean (SD) | 1.07 (0.31) | 1.22 (0.40) | 0.131 | |
Low-density lipoprotein (mmol/L), mean (SD) | 2.75 (0.69) | 2.32 (0.66) | 0.015 | |
C reactive protein (mg/L), mean (SD) | 2.83 (2.81) | 4.69 (4.97) | 0.114 | |
d-dimer (µg/mL), mean (SD) | 0.20 (0.12) | 0.59 (0.83) | 0.012 |