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Table 1 Basic characteristics of young and old groups

From: Lysophospholipids and branched chain amino acids are associated with aging: a metabolomics-based study of Chinese adults

Variables

 

Young (n = 32)

Old (n = 32)

p value

General information

Age (years), mean (SD)

53.59 (5.71)

76.06 (8.64)

 < 0.001

 

Male, no (%)

24 (75)

24 (75)

1.000

 

Weight (Kg), mean (SD)

76.39 (14.67)

69.28 (9.98)

0.027

 

Height (cm), mean (SD)

170.47 (8.15)

167.53 (5.97)

0.105

 

BMI (Kg/m2), mean (SD)

26.17 (4.01)

24.63 (3.03)

0.089

 

Smoking, no (%)

11 (34.4)

8 (25.0)

0.412

 

Drinking, no (%)

13 (40.6)

6 (18.8)

0.055

Physical capacity

Gait speed (m/s), mean (SD)

1.14 (0.38)

0.84 (0.42)

0.011

 

Grip strength (Kg), mean (SD)

38.5 (8.7)

28.5 (8.4)

 < 0.001

Blood pressure

SBP (mmHg), mean (SD)

131.97 (16.89)

136.53 (19.19)

0.317

 

DBP (mmHg), mean (SD)

80.06 (10.46)

72.97 (12.70)

0.018

 

PP (mmHg), mean (SD)

51.91 (13.66)

63.56 (16.06)

0.003

Medical history

Hypertension, no (%)

21 (65.6)

24 (75)

0.412

 

Coronary heart disease, no (%)

4 (12.5)

9 (28.1)

0.120

 

Chronic obstructive pulmonary disease, no (%)

0 (0.0)

1 (3.1)

0.313

 

Cerebravascular accident, no (%)

3 (9.4)

13 (40.6)

0.004

 

Type 2 diabetes mellitus, no (%)

13 (40.6)

13 (40.6)

1.000

 

Number of chronic diseases, mean (SD)

2.91 (2.29)

5.41 (3.11)

0.001

 

Number of drugs, mean (SD)

3.03 (2.21)

5.72 (3.07)

 < 0.001

Laboratory tests

Creatinine (µmol/L), mean (SD)

66.50 (21.69)

76.44 (27.27)

0.112

 

CCr (mL/(min*1.73 m2)), mean (SD)

119.17 (33.88)

75.91 (29.25)

 < 0.001

 

Alanine aminotransferase (IU/L), mean (SD)

24.53 (12.61)

22.00 (12.55)

0.424

 

Aspartate aminotransferase (IU/L), mean (SD)

23.65 (4.77)

24.19 (8.01)

0.746

 

Albumin (g/L), mean (SD)

41.35 (2.77)

38.98 (3.73)

0.007

 

Hemoglobin (g/L), mean (SD)

146.53 (13.70)

133.69 (14.87)

0.001

 

Triglycerides (mmol/L), mean (SD)

2.08 (1.10)

1.53 (1.04)

0.052

 

Total cholesterol (mmol/L), mean (SD)

4.51 (0.78)

3.97 (0.86)

0.015

 

High-density lipoprotein (mmol/L), mean (SD)

1.07 (0.31)

1.22 (0.40)

0.131

 

Low-density lipoprotein (mmol/L), mean (SD)

2.75 (0.69)

2.32 (0.66)

0.015

 

C reactive protein (mg/L), mean (SD)

2.83 (2.81)

4.69 (4.97)

0.114

 

d-dimer (µg/mL), mean (SD)

0.20 (0.12)

0.59 (0.83)

0.012

  1. SD standard deviation, BMI body mass index, SBP, systolic blood pressure, DBP diastolic blood pressure, PP pulse pressure, CCr creatinine clearance