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Table 4 Univariate Cox regression models for the prediction of poor prognosis

From: Role of crescents for lupus nephritis in clinical, pathological and prognosis: a single-center retrospective cohort study

Factors

Univariate

Hazard ratio

95% confidence interval

P value

Gender = male

1.46

0.65–3.24

0.356

Age (year)

1.02

1–1.05

0.078

BMI

1.03

0.94–1.13

0.550

MBP (mmHg)

1.02

1–1.03

0.035

Serum creatinine (μmol/L)

1

1–1.01

0.224

eGFR

0.99

0.98–1

0.062

Serum albumin (g/L)

1

0.96–1.04

0.874

WBC count (10^9/L)

1.02

0.93–1.11

0.679

Hemoglobin (g/L)

0.99

0.98–1

0.191

Platelet (10^9/L)

1

1–1

0.722

Proteinuria (g/24 h)

1.02

0.93–1.13

0.664

Urinary albumin/creatinine ratio (mg/μmol)

1.41

0.81–2.46

0.229

Urine WBC (/HP)

1.02

1–1.04

0.087

Urine RBC (/HP)

1

1–1

0.951

C3 (g/L)

0.82

0.25–2.7

0.739

C4 (g/L)

0.14

0–9.59

0.358

Positive ANA

2.24

1.41–3.55

 < 0.001

Positive anti-dsDNA

2.06

1.39–3.05

 < 0.001

SLEDAI

1.03

1–1.07

0.082

Modified NIH index

 AI

1.07

1.01–1.15

0.034

 CI

1.22

1.1–1.34

 < 0.001

Crescent

 Non-crescent

refer

  

 Crescent

1.74

1.18–2.57

0.006

Treatment

 Steroid dosage (g)

1.04

1.02–1.07

0.001

 Proportion of pulse (g)

1.29

0.51–3.24

0.587

 Pulse dosage (g)

0.95

0.47–1.92

0.878

 CTX dosage (g)

1.05

0.97–1.14

0.229

  1. BMI body mass index, MBP mean blood pressure, eGFR estimated glomerular filtration rate, WBC white blood cells, RBC red blood cells, C3 complement factor 3, C4 complement factor 4, ANA antinuclear antibodies, dsDNA double-stranded DNA, SLEDAI systemic lupus erythematosus disease activity index, NIH National Institutes of Health, AI activity NIH index, CI chronicity NIH index, Pulse methylprednisolone pulse, CTX cyclophosphamide