Table 1 Characteristics of the study population
Variables, n (%) or mean (SD) | LDA (n = 115) | Control (n = 151) | P |
|---|---|---|---|
Maternal age (years) | 31.99 (5.31) | 32.38 (5.47) | 0.5639 |
Delivery gestational age (week) | 37.57 (1.73) | 37.40 (1.91) | 0.4543 |
Pre-pregnancy BMI (kg/m2) | 25.81 (4.57) | 24.19 (4.41) | 0.0038 |
High risk factors | 0.0560 | ||
History of PE | 3 (2.61%) | 7 (4.64%) | 0.5220 |
Multiple pregnancy | 24 (20.87%) | 33 (21.85%) | 0.8463 |
Chronic hypertension | 7 (6.09%) | 3 (1.99%) | 0.1065 |
Pre-existing diabetes | 11 (9.57%) | 8 (5.30%) | 0.1807 |
Kidney disease | 0 (0.00%) | 3 (1.99%) | 0.2610 |
Autoimmune diseases | 1 (0.87%) | 0 (0.00%) | 0.4323 |
Intermediate risk factors | 0.1882 | ||
Nulliparous | 56 (48.70%) | 77 (50.99%) | 0.7104 |
Obese (BMI ≥ 30 kg/m2) | 26 (22.61%) | 30 (19.87%) | 0.5870 |
Family history of PE | 4 (3.48%) | 6 (3.97%) | 0.8334 |
Age (≥ 35 years) | 42 (36.52%) | 72 (47.68%) | 0.0684 |
Clinical indicators | |||
D-dimer (μg/L) | 2273.90 (1212.50) | 2476.60 (1827.30) | 0.2790 |
Platelet count (109/L) | 197.00 (62.92) | 195.80 (56.86) | 0.8735 |
Platelet aggregation rate (%) | 70.30 (5.37) | 67.89 (4.38) | 0.0017 |
Fibrinogen (g/L) | 4.01 (0.82) | 3.62 (0.69) | < 0.0001 |
Prothrombin time (s) | 11.35 (0.89) | 11.13 (0.87) | 0.0504 |
S/D value of uterine artery | 2.31 (0.35) | 2.29 (0.35) | 0.5406 |