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Table 4 The incidence of PE between two groups according to maternal ACOG risk factors

From: Aspirin 75 mg to prevent preeclampsia in high-risk pregnancies: a retrospective real-world study in China

Risk factor

Total

Number of participants

PE patients, n(%) 

OR (95%CI)

P

P for interaction

LDA

Control

LDA

Control

Age (years)

       

0.0023

 ≥ 35

114

42

72

3 (7.14%)

10 (13.89%)

0.48 (0.12–1.84)

0.367

 

 < 35

152

64

55

9 (14.06%)

24 (43.64%)

0.32 (0.14–0.75)

0.007

 

BMI(kg/m2)

       

0.0331

 ≥ 30

56

26

30

4 (15.38%)

9 (30.00%)

0.42 (0.11–1.59)

0.196

 

 < 30

210

89

121

8 (8.99%)

25 (20.66%)

0.38 (0.16–0.89)

0.022

 

History of PE

       

0.0002

 Yes

10

3

7

0 (0.00%)

5 (71.43%)

0.083

 

 No

256

112

144

12 (10.71%)

29 (20.14%)

0.48 (0.23–0.98)

0.041

 

Family history of PE

       

0.0013

 Yes

10

4

6

0 (0.00%)

4 (66.67%)

0.071

 

 No

256

111

145

12 (10.81%)

30 (20.69%)

0.47 (0.23–0.96)

0.034

 

Pre-existing diabetes

       

0.0654

 Yes

19

11

8

2 (18.18%)

2 (25.00%)

0.67 (0.07–6.11)

0.719

 

 No

247

104

143

10 (9.62%)

32 (22.38%)

0.37 (0.17–0.79)

0.008

 

Chronic hypertension

       

0.0003

 Yes

10

7

3

4 (57.14%)

1 (33.33%)

2.67 (0.16–45.13)

0.417

 

 No

256

108

148

8 (7.41%)

33 (22.30%)

0.28 (0.12–0.63)

0.001

 

Nulliparous

       

0.0716

 Yes

133

56

77

7 (12.50%)

17 (22.08%)

0.50 (0.19–1.31)

0.156

 

 No

133

59

74

5 (8.47%)

17 (22.97%)

0.31 (0.11–0.90)

0.025

 

Multiple pregnancy

       

0.0626

 Yes

57

24

33

3 (12.50%)

6 (18.18%)

0.64 (0.14–2.88)

0.720

 

 No

209

91

118

9 (9.89%)

28 (23.73%)

0.35 (0.16–0.79)

0.009

 
  1. PE preeclampsia, ACOG American college of obstetricians and gynecologists, LDA low-dose aspirin, OR (95%CI), odds ratio (95% confidence interval), BMI body mass index.
  2. P-values <0.05 are emphasized in bold font.