Fig. 6

Boxplots of Stochastic Epigenetic Mutations (SEMs). Boxplots showing the distribution of SEMs in “mild” and “severe” patients in a our study, b GSE167202, and c GSE174818. The left panel shows the non-transformed SEMs values while in the panel on the right the log10 transformed SEMs values. The thick horizontal line in the box represents the median of the distribution while the box represents the interquartile range. Whiskers are the default option for the “ggplot2” boxplot function and extend to the most extreme data point, which is no more than 1.5 times the interquartile range from the box. Dots represent outliers (single values exceeding 1.5 interquartile ranges)