Characteristics | Mild (References) Cohort | Severe (Cases) Cohort | p-value |
---|---|---|---|
N = 123 | N = 64 | ||
Host factors | |||
Age (years)—Median (IQR) | 62 (21–90) | 66.8 (30–95) | > 0.05 |
Gender—(Male/Female) | 1.5 | 2.5 | > 0.05 |
ICU admission | 0.0 | 68.0% | – |
Death | 0.0 | 48.0% | – |
Smoke | 21.0% | 14.0% | > 0.05 |
Fever(> 37.3 °C) | 24.0% | 40.0% | 0.03 |
Comorbilities | |||
Obesity | 13.0% | 14.0% | > 0.05 |
Hypertension | 51.2% | 67.1% | > 0.05 |
Diabetes | 16.2% | 50.0% | 2.4 e-6 |
Cardiovascular/Coronary heart disease | 38.2% | 32.8% | > 0.05 |
Respiratory disease | 14.6% | 23.4% | > 0.05 |
Cerebrovascular disease | 5.6% | 7.8% | > 0.05 |
History of cancer | 12.1% | 3.1% | > 0.05 |
No comorbility | 17.8% | 6.5% | > 0.05 |
Biochemical parameters | |||
Elevated creatinine (> 1.33 mg/dL) | 4.0% | 7.0% | > 0.05 |
Reduced albumine (< 4 g/dL) | 82.2% | 92.3% | > 0.05 |
Elevated AsT (> 40 U/L) | 26.6% | 53.8% | > 0.05 |
Elevated LDH (> 245 mU/ml) | 60.0% | 76.9% | > 0.05 |
Elevated C reactive protein (> 8.2 mg/L) | 31.0% | 61.5% | > 0.05 |
Elevated D-dimer (> 1000 ng/mL) | 48.8% | 69.2% | > 0.05 |
Elevated white cell count (> 4 × 109/L) | 0.0% | 0.0% | > 0.05 |