Table 2 Fractionation schemes, therapeutic modalities, effectiveness and reported side effects of the radiation therapy of lymphatic fistulas
Cohort | Treatment period | Number of treated fistulas | Fraction dose | Number of fractions | Beam energy | Response rate | Treatment-related side effects |
|---|---|---|---|---|---|---|---|
Middlesex (Croft 1978 [15]) | 1978 | 1 | 3.0 Gy | 5 | N.A | 100% | N.A |
Karlsruhe (Neu 2000 [4]) | 1989–1998 | 26 | 1.0 Gy | 3–12 | 7–18 MeV e− | 92% | N.A |
Regensburg I (Dietl 2005 [5]) | 1997–2000 | 28 | 3.0 Gy | 3–5 | 120–300 kV | 96% | 0 |
Graz (Mayer 2005 [10]) | 1987–2002 | 11 8 | 0.3–0.5 Gy 1.0–2.0 Gy | up to 16 up to 8 | 100 kV 4–11 MeV e− | 82% 75% | 0 |
Kazan (Kamalov 2010 [12]) | 2009–2010 | 5 | 0.06–0.3 Gy | 3–10 | 180 kV | 100% | N.A |
Zaporozhye (Buga 2012 [14]) | 2008–2012 | 58 | 0.4–0.5 Gy | 2–5 | 180 kV | 67% | 0 |
Regensburg II (Hautmann 2021 [7]) | 2005–2016 | 206 | 3.0 Gy | up to 6 | 6/15 MV | 88% | 0 |
Regensburg BHB (Uhl 2020 [1]) | 2007–2018 | 50 | 1.0 Gy | 3–10 | N.A | 78% | 0 |
Santander (Cañón 2021 [9]) | 2008–2018 | 43 | 1.5 Gy | 3–5 | 6–18 MV | 93% | 0 |
Düsseldorf (present work) | 2019–2022 | 12 | 0.3–0.4 Gy | 2–10 | 6–15 MV | 100% | 0 |