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Fig. 1 | European Journal of Medical Research

Fig. 1

From: Autophagy impairment in patients with obstructive sleep apnea modulates intermittent hypoxia-induced oxidative stress and cell apoptosis via hypermethylation of the ATG5 gene promoter region

Fig. 1

Impaired autophagy flux in patients with obstructive sleep apnea (OSA) and those with specific phenotypes. A LC3B protein expression of blood monocyte was decreased in OSA patients versus subjects with primary snoring (PS). B ATG5 protein expression of blood neutrophil was decreased in OSA patients versus PS subjects. C LC3B protein expression of blood monocyte was negatively correlated with apnea hyponea index (AHI). D P62 protein expression of blood cytotoxic T cell was increased in OSA patients versus PS subjects, and E positively correlated with oxygen desaturation index (ODI). F LC3B protein expression of blood helper T cell was decreased in sleep disordered breathing (SDB) patients with depression versus those without depression. G ATG5 protein expression of blood monocyte was decreased in SDB patients with subjective daytime fatigue versus those without fatigue. H Percentage of blood ATG5 ( +) helper T cell was negatively correlated with arousal index of total sleep time. I P62 protein expression of blood cytotoxic T cell was increased in SDB patients with nocturia versus those with nocturia

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