Fig. 2

Decreased gene expressions of the autophagy-related genes (ATG) in OSA patients and those with excessive daytime sleepiness. A Percentage of blood p62( +) neutrophil was reduced after > 6-month continuous positive airway pressure treatment at home in five OSA patients. B ATG5 gene expression of peripheral blood mononuclear cells (PBMCs) was decreased in OSA patients versus PS subjects, and C negatively correlated with snoring index of total sleep time. D BECN1 gene expression of PBMCs was decreased in OSA patients versus PS subjects, and E negatively correlated with percent time of SpO2 less than 90% during rapid eye movement sleep. F ULK1 gene expression of PBMCs was decreased in OSA patients versus PS subjects, and G positively correlated with minimum SpO2 of total sleep time. H ULK1 gene expression was further decreased in sleep disordered breathing (SDB) patients with excessive daytime sleepiness (EDS) versus those without EDS, and I negatively correlated with Epworth Sleepiness Scale