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Table 1 Clinical characteristics and bleeding outcomes in Chinese patients with ACS

From: miR-6076 rs1463411 polymorphisms are associated with bleeding during clopidogrel treatment in patients with acute coronary syndrome

Characteristics

Total cohort

Bleeding

Non-bleeding

P

n = 563

n = 37

n = 526

Age (Years)

62.98 ± 11.49

59.38 ± 11.95

63.24 ± 11.42

0.048

Sex (Male)—No. (%)

413 (73.4)

32 (86.5)

381 (72.4)

0.082

Risk factors—No. (%)

 

 Familial history of CAD

107 (19.0)

10 (27.0)

97 (18.4)

0.197

 Active cigarette smoking

279 (49.6)

20(54.1)

259 (49.2)

0.613

 Arterial hypertension

401 (71.2)

22 (59.5)

379 (72.1)

0.131

 Hyperlipidemia

302 (53.6)

17 (45.9)

285 (54.2)

0.395

 Diabetes mellitus

183 (32.5)

13 (35.1)

170 (32.3)

0.856

Drug therapy—No. (%)

 

 Statin

537 (95.4)

36 (97.3)

501 (95.2)

1

 β-Receptor blocker

446 (82.8)

27 (73.0)

439 (83.5)

0.115

 ACEI/ARB

354 (62.9)

11 (29.7)

343 (65.2)

 < 0.001

 CCB

250 (44.4)

13 (35.1)

237 (45.1)

0.350

 PPI

68 (12.1)

8 (21.6)

60 (11.4)

0.071

 Aspirin

547 (97.2)

36 (97.3)

511 (97.1)

1

  1. ACS acute coronary syndrome; ACEI angiotensin-converting enzyme inhibitor; ARB angiotensin-receptor blocker; CAD Coronary artery disease; CCB calcium channel blocker; PPI proton-pump inhibitor