The efficacy of high-flow nasal cannula (HFNC) versus non-invasive ventilation (NIV) in patients at high risk of extubation failure: a systematic review and meta-analysis

Table 2 Sensitivity analysis on effects of HFNC on respiratory function indices

Outcome	Before sensitivity analysis			Remove study	After sensitivity analysis
Outcome	Effect estimate	P	I² (%)	Remove study	Effect estimate	P	I² (%)
PaCO₂	− 1.31(− 2.76, 0.13)	0.07	81	Yang et al. 2016	− 0.63(− 1.46, -0.20)	0.14	40
PaO₂/ FiO₂	− 2.18(− 8.49, 4.13)	0.50	57	Yang et al. 2016	1.21(− 3.29, 5.71)	0.60	21
RR	− 0.50(− 1.88, 0.88)	0.47	80	Yang et al. 2016	− 0.13(− 0.85, 1.11)	0.80	57

Effect estimate: risk ratio (95% confidence interval)
PaCO₂: partial pressure of carbon dioxide, P/F: oxygenation index, Rr: respiratory rate

ISSN: 2047-783X