From: Metastasis of breast cancer to bones alters the tumor immune microenvironment
Variable | Median | IQR |
---|---|---|
Stroma (%) | 70 | 40–80 |
Stromal TILs (%) | 5 | 5–10 |
Stromal CD4 + TILs (/mm2) | 12.5 | 1–27.5 |
Stromal CD8 + TILs (/mm2) | 5 | 1–35 |
CD4/CD8 ratio | 1 | 0.53–5.18 |
Stromal HLA-DR + macrophages (/mm2) | 85 | 60–120 |
Stromal CD68 + macrophages (/mm2) | 37.5 | 12.5–57.5 |
HLA-DR/CD68 ratio | 2.27 | 1.44–5 |
PD-1 expression | 43/63 | 68.25 (%) |
PD-L1 expression | 5/63 | 7.94 (%) |
Osteoclasts (/mm2) | 0.33 | 0–3 |