Fig. 2

IGS risk model accurately predicted survival of HCC patients. A, the prognostic value of IGS was validated in the TCGA training cohort, TCGA internal testing cohort, and external ICGC cohort by Kaplan–Meier analysis. B, time-dependent ROC curves of IGS in the three cohorts above. C, the DFS of the high or low IGS risk group in the CHCC cohort. D, the OS curve and time-dependent ROC curves with high or low IGS risk group in CHCC cohort. E, The Univariate and Multivariate Cox regression analyses were performed on 6 variables, including IGS risk score, Age, Gender, Grade, TNM stage, and TP53 status in the pooled TCGA cohort. F, the Univariate and Multivariate Cox regression analyses with IGS risk score, Age, Gender, tumor size, BCLC stage and TP53 status were performed in the CHCC cohort