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Fig. 7 | European Journal of Medical Research

Fig. 7

From: Acute subdural haematoma exacerbates cerebral blood flow disorder and promotes the development of intraoperative brain bulge in patients with severe traumatic brain injury

Fig. 7

BBB and TJ protein damage in the various groups. a Observation of the overall EB-stained brain tissue and coronal sections shows the presence of EB extravasation accompanied by obvious localised haemorrhagic foci after compression by SDH (red arrows). b Comparison of the proportion of EB extravasation at an absorbance of 620 nm/g. c Western blot analysis of TJ protein expression in various groups. d Quantitative analysis of CLDN5, Occluding, and ZO-1 protein expression using the β-actin normalisation method. n = 5 in the sham group and 10 per group in the rest. *P < 0.05, #P < 0.01. BBB: blood–brain barrier; CLDN5: Claudin proteins; EB: Evans blue; SDH: subdural haematoma; TJ: tight junction

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European Journal of Medical Research

ISSN: 2047-783X

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