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Table 1 Collagen metabolism-associated gene expression (fold change)

From: Evaluation of an ex vivo fibrogenesis model using human lung slices prepared from small tissues

 

Col 1a1

α-SMA

MMP 1

MMP 2

MMP 7

MMP 9

Mean

SEM

Mean

SEM

Mean

SEM

Mean

SEM

Mean

SEM

Mean

SEM

Cd

3.59

2.62

5.39

3.90

2.41

1.59

3.69*

0.88

6.42

4.03

3.22*

0.92

TGF-β1

2.20

0.97

1.02

0.01

1.57

0.99

2.15**

0.15

1.54

1.16

4.91**

1.57

Cd + TGF-β1

1.45

0.75

1.82

0.59

4.50

3.02

3.54

1.48

2.61

1.69

2.66

1.26

  1. The Indicated fold change of gene expression is a relative value in comparison with the untreated group, value in each data point was collected from at least 3 independent experiments. Following the statistical analysis, a P values were obtained, where * and ** indicate a P value of < 0.05 and < 0.01, respectively