Table 1 General characteristics of patients in a case–control study of post-dialysis fatigue
Characteristic | Study patients (n = 610) | Fatigue (n = 340) | Non-Fatigue (n = 270) | P |
|---|---|---|---|---|
Age, years | 58 (47–66) | 59 (49–67) | 56 (46–64) | 0.02 |
Male, n (%) | 375 (61.48) | 203 (59.71) | 172 (63.70) | 0.31 |
Time on dialysis, months | 51(24–99) | 50.5(25.5–101) | 51.5 (23–95) | 0.37 |
BMI (kg/m2) | 23.5 (21–26.1) | 23.80 (21.05–26.20) | 23.20 (20.9–25.7) | 0.17 |
Primary disease, n (%) | 0.07 | |||
Diabetic nephropathy | 202 (33.11) | 116 (34.12) | 86 (31.85) | |
Glomerulonephritis | 239 (39.18) | 127 (37.75) | 112 (41.48) | |
Hypertensive nephropathy | 99 (16.23) | 65 (19.12) | 34 (12.59) | |
Polycystic kidney | 33 (5.41) | 13 (3.82) | 20 (7.41) | |
Others | 37 (6.07) | 19 (5.59) | 18 (6.67) | |
Residual renal function [yes, n (%)] | 227 (37.21) | 118 (34.71) | 109 (40.37) | 0.15 |
Hypertension [yes, n (%)] | 453 (75.75) | 250 (75.08) | 203 (76.60) | 0.66 |
Diabetes [yes, n (%)] | 223 (37.29) | 124 (37.24) | 99 (37.36) | 0.98 |
Daily exercise time n (%) | < 0.01 | |||
No | 242 (39.67) | 156 (45.88) | 86 (31.85) | < 0.01 |
Less than 1 h | 181 (29.67) | 108 (31.76) | 73 (27.04) | 0.20 |
1–2 h | 123 (20.16) | 50 (14.71) | 73 (27.04) | < 0.01 |
Greater than 2 h | 64 (10.49) | 26 (7.65) | 38 (14.07) | 0.01 |
UFR, ml/kg∙h | 0.74 | |||
< 12.5 | 567 (92.95) | 315 (92.65) | 252 (93.33) | |
≥ 12.5 | 43 (7.05) | 25 (7.35) | 18 (6.67) | |
Hemoglobin, g/L | 113 (102–122) | 112.5 (100.5–122) | 113 (104–121) | 0.46 |
Albumin, g/L | 41.9 (39.5–43.8) | 41.5 (39.30–43.55) | 42.2 (40–44) | 0.01 |
Urea nitrogen, mmol/L | 26.25 (22.65–30.03) | 26.20 (22.75–30.11) | 26.30 (22.40–30.01) | 0.68 |
C-reactive protein, mg/L | 3.14(3.14–7.71) | 3.36 (3.14–7.74) | 3.14 (3.14–7.62) | 0.49 |
Phosphorus, mmol/L | 1.99 (1.66–2.40) | 1.99 (1.66–2.41) | 1.99 (1.64–2.35) | 0.68 |
Calcium, mmol/L | 2.42 ± 0.12 | 2.43 ± 0.12 | 2.40 ± 0.13 | < 0.01 |
Single-pool Kt/Vurea | 1.31 (1.17–1.47) | 1.31 (1.17–1.47) | 1.31 (1.18–1.47) | 0.74 |
Pre-dialysis sodium, mmol/L | 137.43 ± 3.41 | 137.34 ± 3.47 | 137.55 ± 3.35 | 0.44 |
Post-dialysis sodium, mmol/L | 136.01 ± 2.29 | 136.07 ± 2.30 | 135.93 ± 2.28 | 0.46 |
Magnesium, mmol/L | 1.09 (1.02–1.19) | 1.10 (1.02–1.19) | 1.09 (1.01–1.18) | 0.57 |
iPTH, pg/mL | 497.30 (278.10–803.90) | 479.15 (274.45–804.75) | 506.65 (280.80–797) | 0.54 |