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  1. Elabela, a recently discovered hormonal peptide containing 32 amino acids, is a ligand for the apelin receptor. It can lower blood pressure and attenuate renal fibrosis. However, the clinicopathological relati...

    Authors: Geng Tian, Qian Zheng, Qingru Zhang, Xiaoyu Liu and Xuehong Lu
    Citation: European Journal of Medical Research 2024 29:94
  2. BCL-2-associated athanogene 3 (BAG3) is an anti-apoptotic protein that plays an essential role in the onset and progression of multiple cancer types. However, the clinical significance of BAG3 in kidney renal ...

    Authors: Binghao Gong, Yuan Huang, Zhenting Wang, Bangbei Wan, Yaohui Zeng and Cai Lv
    Citation: European Journal of Medical Research 2024 29:93
  3. Prostate cancer (PCa) is the most prevalent genitourinary malignancy in men, with a significant proportion of patients developing biochemical recurrence (BCR) after treatment. The immune microenvironment and m...

    Authors: Bintao Hu, Xi Zhang, Shiqing Zhu, Chengwei Wang, Zhiyao Deng, Tao Wang and Yue Wu
    Citation: European Journal of Medical Research 2024 29:92
  4. The diagnostic process for fibrotic interstitial lung disease (F-ILD) is notably intricate, necessitating a multidisciplinary discussion to achieve consensus based on both clinical and radiological features. T...

    Authors: Yu-Wan Liao, Ming-Cheng Liu, Yu-Cheng Wu, Chiann-Yi Hsu, Wen-Nan Huang, Yi-Hsing Chen and Pin-Kuei Fu
    Citation: European Journal of Medical Research 2024 29:91
  5. Cancer is a disease that can cause abnormal cell growth and can spread throughout the body. It is among the most significant causes of death worldwide, resulting in approx. 10 million deaths annually. Many syn...

    Authors: Priyanka Sati, Eshita Sharma, Praveen Dhyani, Dharam Chand Attri, Rohit Rana, Lashyn Kiyekbayeva, Dietrich Büsselberg, Samson Mathews Samuel and Javad Sharifi-Rad
    Citation: European Journal of Medical Research 2024 29:90
  6. Kidney cancer is an immunogenic solid tumor, characterized by high tumor burden and infiltration of CD8+ T cells. Although immunotherapy targeting the PD1/CTLA-4 axis has demonstrated excellent clinical efficacy,...

    Authors: Haifeng Gao, Hang Sun, Aifeng He, Hui Liu, Zihang Zhang, Dongling Li, Weipu Mao and Jinke Qian
    Citation: European Journal of Medical Research 2024 29:89
  7. Prostate cancer poses a considerable threat to human health. At present, the mechanism of tumor progression remains unclear. ZNF692 is overexpressed in many tumors, and the high expression of ZNF692 is correla...

    Authors: Hanmin Chen, Yanmin Li, Gengqing Wu, Qingming Zeng, Haibing Huang and Guoxi Zhang
    Citation: European Journal of Medical Research 2024 29:88
  8. To compare the clinical effects of intramedullary elastic reduction of the “de-sharpened Kirschner wire and traditional three-dimensional manipulation in the treatment of Gartland type III posterolateral supra...

    Authors: Yudong Lin, Zhongtuo Hua, Cheng Zhou, Saiwen Chen, Xiwei Sun, Fang Liu, Ge Meng, Sicheng Zhang and Jun Sun
    Citation: European Journal of Medical Research 2024 29:87
  9. The aim of this study was to evaluate the association between gingival crevicular blood glucose levels (GCBG) and finger capillary blood glucose levels (FCBG) according to the periodontal status of patients.

    Authors: Somaye Ansari Moghadam, Hanie Abbaszade, Mohadeseh Sartipi and Alireza Ansari Moghadam
    Citation: European Journal of Medical Research 2024 29:86
  10. The risk and timing of permanent pacemaker implantation (PPMI) after transcatheter aortic valve replacement (TAVR) is still hard to predict. We aimed to analyze the relationship between the compression ratio o...

    Authors: Yiming Qi, Yuefan Ding, Wenzhi Pan, Xiaochun Zhang, Xiaolei Lin, Shasha Chen, Lei Zhang, Daxin Zhou and Junbo Ge
    Citation: European Journal of Medical Research 2024 29:85
  11. To use deep learning to segment the mandible and identify three-dimensional (3D) anatomical landmarks from cone-beam computed tomography (CBCT) images, the planes constructed from the mandibular midline landma...

    Authors: Yali Wang, Weizi Wu, Mukeshimana Christelle, Mengyuan Sun, Zehui Wen, Yifan Lin, Hengguo Zhang and Jianguang Xu
    Citation: European Journal of Medical Research 2024 29:84
  12. Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap (SJS/TEN), collectively referred to SJS/TEN, form a spectrum of severe life-threatening adverse drug reactions whose pathom...

    Authors: Bukiwe N. Thwala, Nadine Teixeira, Eddy Zitha, Aneliswa Mpungose, Thuraya Isaacs, Jonathan G. Peter and Rannakoe J. Lehloenya
    Citation: European Journal of Medical Research 2024 29:83
  13. Cadmium (Cd) exposure has been found to have detrimental effects on the development of the central nervous system and cognitive ability in children. However, there is ongoing debate regarding the impact of mat...

    Authors: Hui Liu, Xichen Wan, Liyun Yao, Qihan Zhao, Yong Yang, Hongtao Liu, Jun Shang, Fanfan Zeng, Xin Wang and Shaoxin Huang
    Citation: European Journal of Medical Research 2024 29:82
  14. Stroke stands as the second leading cause of death worldwide. Currently, extensive research has been conducted on stroke risk factors. However, when stroke patients contend with multiple risk factors, the impa...

    Authors: Jiejie Guo, Mei Tian, Yongang Li, Yitong Guo, Ting Zhang, Xuan Liu, Jinze Shen, Lin Zhang, Yueqi Yu, Ling Cao, Haiyan Gu, Yanfang Li, Shiwei Duan and Qinwen Wang
    Citation: European Journal of Medical Research 2024 29:81
  15. The incidence of cervical spine fractures is increasing every day, causing a huge burden on society. This study aimed to develop and verify a nomogram to predict the in-hospital mortality of patients with cerv...

    Authors: Zhibin Xing, Lingli Cai, Yuxuan Wu, Pengfei Shen, Xiaochen Fu, Yiwen Xu and Jing Wang
    Citation: European Journal of Medical Research 2024 29:80
  16. MDM4 is one of the MDM protein family and is generally recognized as the key negative regulator of p53. As a cancer-promoting factor, it plays a non-negligible role in tumorigenesis and development. In this ar...

    Authors: Jie Liu, Jie Yang, Qilong Pan, Xiangyu Wang, Xinyin Wang, Han Chen, Xiaoling Zheng and Qingling Huang
    Citation: European Journal of Medical Research 2024 29:79
  17. Allergic rhinitis (AR) and migraine are among the most common public health problems worldwide. Observational studies on the correlation between AR and migraine have reported inconsistent results. This study a...

    Authors: Hao Lv, Kunyu Liu, Yulie Xie, Yunfei Wang, Siyuan Chen, Peiqiang Liu, Mengting Guan, Jianchao Cong and Yu Xu
    Citation: European Journal of Medical Research 2024 29:78
  18. Acute kidney injury (AKI) is one of the preventable complications of percutaneous coronary intervention (PCI). This study aimed to develop machine learning (ML) models to predict AKI after PCI in patients with...

    Authors: Amir Hossein Behnoush, M. Moein Shariatnia, Amirmohammad Khalaji, Mahsa Asadi, Alireza Yaghoobi, Malihe Rezaee, Hamidreza Soleimani, Ali Sheikhy, Afsaneh Aein, Somayeh Yadangi, Yaser Jenab, Farzad Masoudkabir, Mehdi Mehrani, Mina Iskander and Kaveh Hosseini
    Citation: European Journal of Medical Research 2024 29:76
  19. Alzheimer's disease is one common type of dementia. Numerous studies have suggested a correlation between Alzheimer's disease and inflammation. Microglia mainly participate in the inflammatory response in the ...

    Authors: Lijie Zhang, Qiuru Yao, Jinjing Hu, Baizhi Qiu, Yupeng Xiao, Qi Zhang, Yuting Zeng, Shuqi Zheng, Youao Zhang, Yantong Wan, Xiaoyan Zheng and Qing Zeng
    Citation: European Journal of Medical Research 2024 29:75
  20. Studies have shown that Caveolin gene polymorphisms (CAV-1) are involved in chronic diseases, such as metabolic syndrome. Moreover, the dietary insulin index (DII) and dietary insulin load (DIL) have been show...

    Authors: Reza Amiri khosroshahi, Atieh Mirzababaei, Leila Setayesh, Reza Bagheri, Mohammad Heidari Seyedmahalleh, Alexei Wong, Katsuhiko Suzuki and Khadijeh Mirzaei
    Citation: European Journal of Medical Research 2024 29:74
  21. Clear-cell renal cell carcinoma (ccRCC) is one of prevalent kidney malignancies with an unfavorable prognosis. There is a need for a robust model to predict ccRCC patient survival and guide treatment decisions.

    Authors: Qinfan Yao, Xiuyuan Zhang, Yucheng Wang, Cuili Wang, Jianghua Chen and Dajin Chen
    Citation: European Journal of Medical Research 2024 29:73
  22. The choice of continuous renal replacement therapy (CRRT) anticoagulation program for patients at high risk of bleeding has always been a complex problem in clinical practice. Clinical regimens include regiona...

    Authors: Dan Liu, Jian Zhao, Hui Xia, Shi Dong, Songjuan Yan, Yugang Zhuang, Yuanzhuo Chen and Hu Peng
    Citation: European Journal of Medical Research 2024 29:72
  23. Sepsis is a major cause of death worldwide, with a mortality rate that has remained stubbornly high. The current gold standard of risk stratifying sepsis patients provides limited mechanistic insight for thera...

    Authors: Pär I. Johansson, Hanne H. Henriksen, Sigurður T. Karvelsson, Óttar Rolfsson, Martin Schønemann-Lund, Morten H. Bestle and Sarah McGarrity
    Citation: European Journal of Medical Research 2024 29:71
  24. Idiopathic pulmonary fibrosis (IPF) stands out as one of the most aggressive forms of interstitial lung diseases (ILDs), currently without a definitive cure. Multidisciplinary discussion (MDD) is now considere...

    Authors: Yu-Wan Liao, Yi-Ming Chen, Ming-Cheng Liu, Yu-Cheng Wu, Chiann-Yi Hsu, Pin-Kuei Fu, Wen-Nan Huang and Yi-Hsing Chen
    Citation: European Journal of Medical Research 2024 29:69
  25. Idiopathic pulmonary fibrosis (IPF) is a devastating chronic lung disease characterized by irreversible scarring of the lung parenchyma. Despite various interventions aimed at mitigating several different mole...

    Authors: Feng Guo, Feng Xu, Shujuan Li, Yun Zhang, Dan Lv, Lin Zheng, Yongxiong Gan, Miao Zhou, Keyu Zhao, Shuling Xu, Bin Wu, Zaichun Deng and Panfeng Fu
    Citation: European Journal of Medical Research 2024 29:68
  26. Previously characterized as an oncogenic player in breast cancer, the function of circular RNA NINL (circNINL) in lung cancer (LC) remained elusive. This study aimed to delineate the biological role of circNIN...

    Authors: Sai Li, Chun Qiu, DaTong Sun, ShengHui Yang and Lin Wang
    Citation: European Journal of Medical Research 2024 29:67
  27. Adolescent idiopathic scoliosis (AIS) is a common structural deformity of the spine affecting adolescent individuals globally. The disorder is polygenic and is accompanied by the association of various genetic...

    Authors: Hemender Singh, Shipra, Manish Gupta, Nital Gupta, Geetanjali Gupta, Ajay K. Pandita, Rajesh Sharma, Sarla Pandita, Vinod Singh, Bhavuk Garg, Ekta Rai and Swarkar Sharma
    Citation: European Journal of Medical Research 2024 29:66
  28. Asthma represents a significant global challenge that affects individuals across all age groups and imposes substantial social and economic burden. Due to heterogeneity of the disease, not all patients obtain ...

    Authors: Xiangting Ge, Tingting Xu, Meiyan Wang, Lijiao Gao, Yue Tang, Ningjie Zhang, Rui Zheng, Weimin Zeng, Gaozhi Chen, Bing Zhang, Yuanrong Dai and Yali Zhang
    Citation: European Journal of Medical Research 2024 29:65
  29. N-Nitrosomorpholine (NMO) is one of the most common N-nitroso compounds. An oncocytic transformation has been demonstrated in renal tubules of NMO-treated rats. In our study, we aimed to investigate the potential...

    Authors: Emre Gezer, Cüneyt Özer, Turgay Şimşek, Büşra Yaprak Bayrak, Gupse Turan, Berrin Çetinarslan, Alev Selek, Zeynep Cantürk, Mehmet Sözen and Damla Köksalan
    Citation: European Journal of Medical Research 2024 29:64
  30. Prone positioning (PP) is a low-cost method with minimal risk to the patient that improves the oxygenation of patients with acute hypoxic respiratory failure (AHRF) due to COVID-19 pneumonia, thereby reducing ...

    Authors: Sepideh Tahsini Tekantapeh, Nader D. Nader, Morteza Ghojazadeh, Fatemeh Fereidouni and Hassan Soleimanpour
    Citation: European Journal of Medical Research 2024 29:63
  31. Atrial fibrillation (AF) is highly prevalent in the population, yet the factors contributing to AF events in susceptible individuals remain partially understood. The potential relationship between meteorologic...

    Authors: Shanmei Wu, Jingyi Guo, Xin Chen, Jie Wang, Gang Zhao, Shixin Ma, Tianzheng Hao, Jianguo Tan and Yongguang Li
    Citation: European Journal of Medical Research 2024 29:62
  32. The objective of this study was to explore the associations of body mass index (BMI), fat mass index (FMI), skeletal mass index (SMI) and secondary osteoporosis (OP) in patients with rheumatoid arthritis (RA).

    Authors: Yi-ran Chu, Yue-chen Xu, Ling-li Ma, Jian-xiong Wang, He-xiang Zong, Wan-qiu Tong, Xi-le Wang, Xu Zhao and Sheng-qian Xu
    Citation: European Journal of Medical Research 2024 29:61
  33. To investigate the effect of salidroside (SAL) in protecting retinal ganglion cell (RGC) from pyroptosis and explore associated molecular network mechanism in diabetic retinapathy (DR) rats.

    Authors: Lan-Chun Zhang, Na Li, Min Xu, Ji-Lin Chen, Hua He, Jia Liu, Ting-Hua Wang and Zhong-Fu Zuo
    Citation: European Journal of Medical Research 2024 29:60
  34. Authors: Aierpati Maimaiti, Zhaohai Feng, Yanwen Liu, Mirzat Turhon, Zhihao Xie, Yilimire Baihetiyaer, Xixian Wang, Maimaitijiang Kasimu, Lei Jiang, Yongxin Wang, Zengliang Wang and Yinan Pei
    Citation: European Journal of Medical Research 2024 29:59

    The original article was published in European Journal of Medical Research 2023 28:144

  35. A uniform definition of continence is urgently needed to allow the comparison of study results and to estimate patient outcomes after radical prostatectomy (RP). To identify a practical definition that include...

    Authors: Sigrun Holze, Anna Sophie Kuntze, Meinhard Mende, Petra Neuhaus, Michael C. Truss, Hoang Minh Do, Anja Dietel, Toni Franz and Jens-Uwe Stolzenburg
    Citation: European Journal of Medical Research 2024 29:58
  36. The androgen receptor (AR) has been demonstrated to play a role in the pathogenesis of glioblastoma; however, the implications of circulating testosterone levels in the biology of glioblastoma remain unknown.

    Authors: Helga Fariña-Jerónimo, Rita Martín-Ramírez, Rebeca González-Fernández, Lilian Medina, Antonia de Vera, Pablo Martín-Vasallo and Julio Plata-Bello
    Citation: European Journal of Medical Research 2024 29:57
  37. The influence of gender on the epidemiology of and outcome from SA-AKI in ICU has not been fully clarified. Our aim is to elucidate these differences.

    Authors: Wei Jiang, Lin Song, Yaosheng Zhang, Jingjing Ba, Jing Yuan, Xianghui Li, Ting Liao, Chuanqing Zhang, Jun Shao, Jiangquan Yu and Ruiqiang Zheng
    Citation: European Journal of Medical Research 2024 29:56
  38. Patients with autoimmune and immune-mediated diseases (AI-IMD) are at greater risk of COVID-19 infection; therefore, they should be prioritized in vaccination programs. However, there are concerns regarding th...

    Authors: Mahya Shabani, Parnian Shobeiri, Shadi Nouri, Zahra Moradi, Robel Assefa Amenu, Mohammad-Mehdi Mehrabi Nejad and Nima Rezaei
    Citation: European Journal of Medical Research 2024 29:55
  39. To screen characteristic genes related to sarcopenia by bioinformatics and machine learning, and to verify the accuracy of characteristic genes in the diagnosis of sarcopenia. Download myopia-related data sets...

    Authors: Yong Chen, Zhenyu Zhang, Xiaolan Hu and Yang Zhang
    Citation: European Journal of Medical Research 2024 29:54
  40. Previous compelling evidence suggests an association between Type 2 diabetes (T2D) and neurodegenerative diseases. However, it remains uncertain whether Type 1 diabetes mellitus (T1DM) exerts a causal influenc...

    Authors: Chaofan Geng, Ke Meng, Bo Zhao, Xiaoduo Liu and Yi Tang
    Citation: European Journal of Medical Research 2024 29:53
  41. Bladder cancer is an epidemic and life-threating urologic carcinoma. Anoikis is a unusual type of programmed cell death which plays a vital role in tumor survival, invasion and metastasis. Nevertheless, the re...

    Authors: Haoran Wang, Jianyong Liu, Runhua Tang, Jie Hu, Ming Liu, Jianye Wang, Jingwen Zhang and Huimin Hou
    Citation: European Journal of Medical Research 2024 29:52
  42. Glial fibrillary acidic protein (GFAP), an intracellular type III intermediate filament protein, provides structural support and maintains the mechanical integrity of astrocytes. It is predominantly found in t...

    Authors: Xiaoxiao Zheng, Jingyao Yang, Yiwei Hou, Xinye Shi and Kangding Liu
    Citation: European Journal of Medical Research 2024 29:51
  43. Stroke is the second leading cause of death worldwide, and observational studies have suggested a correlation between antioxidants and reduced stroke risk. However, it remains unclear whether causal relationsh...

    Authors: Rundong Chen, Hanchen Liu, Guanghao Zhang, Qian Zhang, Weilong Hua, Lei Zhang, Nan Lv, Yilei Zhang, Dongwei Dai, Rui Zhao, Qiang Li, Qinghai Huang, Yi Xu, Pengfei Yang, Jianmin Liu and Qiao Zuo
    Citation: European Journal of Medical Research 2024 29:50
  44. Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that target the endocannabinoid system in many body organs. SCs can initiate pathophysiological changes in many tissues which c...

    Authors: Ayman Alzu’bi, Fatimah Almahasneh, Ramada Khasawneh, Ejlal Abu-El-Rub, Worood Bani Baker and Raed M. Al-Zoubi
    Citation: European Journal of Medical Research 2024 29:49
  45. Caring for hemodialysis patients could be a heavy burden on family caregivers, causing them to become fatigued and decrease their quality of life. This study aimed to investigate whether Jacobson’s relaxation ...

    Authors: Seyedeh Azam Sajadi, Farzaneh Ravash and Zahra Farsi
    Citation: European Journal of Medical Research 2024 29:46
  46. Epilepsy, a central neurological disorder, has a complex genetic architecture. There is some evidence suggesting that genetic factors play a role in both the occurrence of epilepsy and its treatment. However, ...

    Authors: Shitao Wang, Zhenrong Xie, Tian Jun, Xuelu Ma, Mengen Zhang, Feng Rao, Hui Xu, Jinghong Lu, Xiangqian Ding and Zongyou Li
    Citation: European Journal of Medical Research 2024 29:43
  47. Whether symptomatic unruptured intracranial aneurysms (UIAs) lead to change in circulating inflammation remains unclear. This study aims to evaluate the role of hematological inflammatory indicators in predict...

    Authors: De-Xiang Zheng, Yi-Yang Lv, Xiao-Jing Zhang, Jie-Shun Ye, Jian-Xing Zhang, Cha Chen, Bin Luo and Dan Yan
    Citation: European Journal of Medical Research 2024 29:40

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