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  1. Inflammation is a crucial factor in the pathogenesis and development of acute kidney injury (AKI). Macrophages, as an important innate immune cell, regulate immune response and play a pathophysiological role i...

    Authors: Bo Shen, Zhouping Zou, Yang Li, Ping Jia, Yeqing Xie, Shaomin Gong, Jie Teng, Jiarui Xu, Cheng Yang and Xiaoqiang Ding
    Citation: European Journal of Medical Research 2022 27:312
  2. Identifying breast cancer risk factors is a critical component of preventative strategies for this disease. This study aims to identify modifiable and non-modifiable risk factors of breast cancer in Iranian wo...

    Authors: Malihe Khoramdad, Masoud Solaymani-Dodaran, Ali Kabir, Neda Ghahremanzadeh, Esmat-o-Sadat Hashemi, Noushin Fahimfar, Zahra Omidi, Mohammad Ali Mansournia, Asiie Olfatbakh, Hamid Salehiniya and Shahpar Haghighat
    Citation: European Journal of Medical Research 2022 27:311
  3. Prone position has already been demonstrated to improve survival in non-COVID acute respiratory distress syndrome and has been widely performed in COVID-19 patients with respiratory failure, both in non-intuba...

    Authors: Hyeon-Jeong Lee, Junghyun Kim, Miyoung Choi, Won-Il Choi, Joonsung Joh, Jungeun Park and Joohae Kim
    Citation: European Journal of Medical Research 2022 27:310
  4. To retrospectively investigate the epicardial fat volume with multidetector computed tomography (MDCT) and other risk factors for the prevalence of three-vessel coronary lesion.

    Authors: Bulang Gao, Caiying Li, Qibin Liao, Tong Pan, Chunfeng Ren and Qinying Cao
    Citation: European Journal of Medical Research 2022 27:308
  5. Testosterone has an impact on metabolic disorders and men with type 2 diabetes mellitus (T2DM) are predisposed to hypogonadism; meanwhile, patients with T2DM have higher risk of NAFLD. Therefore, we speculate ...

    Authors: Ziteng Zhang, Chi Chen, Yuying Wang, Ningjian Wang, Yi Chen, Yingli Lu and Fangzhen Xia
    Citation: European Journal of Medical Research 2022 27:307
  6. Charged particle beams from protons to carbon ions provide many significant physical benefits in radiation therapy. However, preclinical studies of charged particle therapy for prostate cancer are extremely li...

    Authors: Tian-Qi Du, Ruifeng Liu, Qiuning Zhang, Hongtao Luo, Yanliang Chen, Mingyu Tan, Qian Wang, Xun Wu, Zhiqiang Liu, Shilong Sun, Kehu Yang, Jinhui Tian and Xiaohu Wang
    Citation: European Journal of Medical Research 2022 27:306
  7. To develop an end-to-end deep learning method for automated quantitative assessment of pediatric blunt hepatic trauma based on contrast-enhanced computed tomography (CT).

    Authors: Shungen Huang, Zhiyong Zhou, Xusheng Qian, Dashuang Li, Wanliang Guo and Yakang Dai
    Citation: European Journal of Medical Research 2022 27:305
  8. The African continent is currently facing an epidemiological transition characterized by a shift from communicable to non-communicable diseases. Prominent amongst the latter are allergies and asthma. In that c...

    Authors: Euripide F. G. A. Avokpaho, Laure Gineau, Audrey Sabbagh, Eloic Atindégla, Arnauld Fiogbé, Sean Galagan, Moudachirou Ibikounlé, Achille Massougbodji, Judd L. Walson, Adrian J. F. Luty and André Garcia
    Citation: European Journal of Medical Research 2022 27:304
  9. Non-adherence of patients with vulvovaginal candidiasis (VVC) to treatment recommendations leads to treatment failure and recurrence of infection. Therefore, this qualitative study was conducted to identify ba...

    Authors: Maryam Erfaninejad, Arash Salahshouri and Nasrin Amirrajab
    Citation: European Journal of Medical Research 2022 27:303
  10. Rapid diagnosis of coronary artery disease has an important role in saving patients. The aim of this study is to evaluate if aVR lead ST-elevation (STE) can predict LM/3VD, left main (LM) disease, and three-ve...

    Authors: Erfan Kazemi, Ali Mansoursamaei, Morteza Bijan, Ali Hosseinzadeh and Hossein Sheibani
    Citation: European Journal of Medical Research 2022 27:302
  11. Adrenocortical carcinoma (ACC) is a rare endocrine neoplasm, which is characterized by poor prognosis and high recurrence rate. Novel and reliable prognostic and metastatic biomarkers are lacking for ACC patie...

    Authors: Xinzhao Zhao, Xuezhou Zhang, Shixiu Shao, Qingbo Yang, Chengquan Shen, Xuecheng Yang, Wei Jiao, Jing Liu and Yonghua Wang
    Citation: European Journal of Medical Research 2022 27:301
  12. According to reports, between 30 and 40 percent of extrapulmonary tuberculosis (EPTB) cases are caused by urinary tract tuberculosis (UTB). It is critical to identify UTB quickly since it frequently precedes d...

    Authors: Yachun Wang, Jiao Tan, Lei Lei, Yingying Yuan, Wenbo Li, Yue Zhao, Yali Wang, Xiaodong Niu, Zheng Li, Lukuan Wei, Yungang Han, Meijing Cheng, Xu Guo, Xue Han and Wei Wang
    Citation: European Journal of Medical Research 2022 27:300
  13. VEGF facilitates tumor angiogenesis, and bevacizumab targeting VEGF is used in anti-tumor therapy. It is meaningful to clarify the upstream regulatory mechanism of VEGF. BPTF is important in chromosomal remode...

    Authors: Meng Dai, Chunyu Hua, Mingqin Wang, Li Gao, Ling Jiang and Yuan Liu
    Citation: European Journal of Medical Research 2022 27:299
  14. The optimal time point for surgical resection of synchronous colorectal liver metastases (SCLMs) is still controversial. This meta-analysis evaluated the safety and long-term prognoses of simultaneous and stag...

    Authors: Shi-hao Wang, Lei Song, Ji-yan Tang, Wei-peng Sun and Zhen Li
    Citation: European Journal of Medical Research 2022 27:297
  15. The inhibitory activities of vitamins K2 against clinical isolates of quinolone-resistant and methicillin-resistant Staphylococcus aureus (QR-MRSA) are unclear. The main aim is to better understand of inhibitory ...

    Authors: Naime Kashefi Pasandideh, Hamed Tahmasebi, Sanaz Dehbashi, Behrouz zeyni and Mohammad Reza Arabestani
    Citation: European Journal of Medical Research 2022 27:295
  16. Early identifying sepsis patients who had higher risk of poor prognosis was extremely important. The aim of this study was to develop an artificial neural networks (ANN) model for early predicting clinical out...

    Authors: Yingjie Su, Cuirong Guo, Shifang Zhou, Changluo Li and Ning Ding
    Citation: European Journal of Medical Research 2022 27:294
  17. Tumor immune microenvironment (TIME) plays a vital role in breast cancer development, treatment resistance, and prognosis. This study evaluates the association of TIME profiling and 21-gene recurrence score (R...

    Authors: Yiwei Tong, Jiahui Huang, Weili Ren, Jing Yu, Xu Zhang, Zheng Wang, Jin Hong, Weiqi Gao, Jiayi Wu, Min Ji, Kunwei Shen and Xiaosong Chen
    Citation: European Journal of Medical Research 2022 27:293
  18. Endometrial carcinoma (EC) is one of the most common female reproductive system tumors, which seriously threatens women's health. This preliminary study aimed to investigate the effects of quercetin on the EC ...

    Authors: Xiaoqin Li, Qianqian Zhu, Meng Ma and Haiyan Guo
    Citation: European Journal of Medical Research 2022 27:292
  19. The emergence of new variants of SARS-CoV-2 is continuously posing pressure to the epidemic prevention and control in China. The Omicron variant of SARS-CoV-2 having stronger infectivity, immune escape ability...

    Authors: Peiyan Zhang, Zhao Cai, Zhiguang He, Peifen Chen, Weibo Wu, Yuanlong Lin, Shiyan Feng, Ling Peng, Jianming Li, Jing Yuan, Liang Yang, Fuxiang Wang, Yingxia Liu and Hongzhou Lu
    Citation: European Journal of Medical Research 2022 27:291
  20. Ventricular premature complex (VPC) is a common arrhythmia in clinical practice. VPC could trigger ventricular tachycardia/fibrillation or VPC-induced cardiomyopathy in susceptible patients. Existing screening...

    Authors: Sheng-Nan Chang, Yu-Heng Tseng, Jien-Jiun Chen, Fu-Chun Chiu, Chin-Feng Tsai, Juey-Jen Hwang, Yi-Chih Wang and Chia-Ti Tsai
    Citation: European Journal of Medical Research 2022 27:289
  21. Osteoarthritis (OA) is a common chronic disabling disease that affects hundreds of millions of people around the world. The most important pathological feature is the rupture and loss of articular cartilage, a...

    Authors: Hanhan Guo, Jianghong Huang, Yujie Liang, Daping Wang and Huawei Zhang
    Citation: European Journal of Medical Research 2022 27:288
  22. Helical tomotherapy (HT) is a viable method for delivering total body irradiation (TBI) when preparing patients for allogenic stem cell or bone-marrow transplantation. TBI can be planned to reduce the amount o...

    Authors: Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Frank A. Giordano, Georgios Chatzikonstantinou and Leonard C. Schmeel
    Citation: European Journal of Medical Research 2022 27:287
  23. Congenital heart defects (CHDs) are the most common congenital malformations, including structural malformations in the heart and great vessels. CHD complications such as low birth weight, prematurity, pregnan...

    Authors: Avisa Tabib, Taravat Talebi, Serwa Ghasemi, Maryam Pourirahim, Niloofar Naderi, Majid Maleki and Samira Kalayinia
    Citation: European Journal of Medical Research 2022 27:286
  24. The effects of diastolic arterial pressure (DAP) and heart rate (HR) on the prognosis of patients with septic shock are unclear, and whether these effects persist over time is unknown. We aimed to investigate ...

    Authors: Wenyan Xiao, Wanjun Liu, Jin Zhang, Yu Liu, Tianfeng Hua and Min Yang
    Citation: European Journal of Medical Research 2022 27:285
  25. Autoimmune hepatitis (AIH) is a chronic immune-mediated inflammatory liver disease. It is known that AIH originates not from the spleen but from the liver itself. Nonetheless, most details of the etiology and ...

    Authors: Janine Dywicki, Laura Elisa Buitrago-Molina, Fatih Noyan, Jerome Schlue, Konstantinos Iordanidis, Michael P. Manns, Heiner Wedemeyer, Elmar Jaeckel and Matthias Hardtke-Wolenski
    Citation: European Journal of Medical Research 2022 27:284
  26. Under the obvious acetabular superolateral bone defect of Crowe II/III hips, this study aimed to investigate the difference in surgical technique of different hip center positions from the surgical data and cl...

    Authors: Cheng-Qi Jia, Hong-Fa Pan, Yu-Jie Wu, Yong-Gang You, Shi-Qi Cao and Xue-Song Zhang
    Citation: European Journal of Medical Research 2022 27:282
  27. To detect the changes in Nel-like 2 (NELL2) in cerebrospinal fluid (CSF) in the outcome of tuberculous meningitis (TBM) patients and to initially evaluate its potential as a marker.

    Authors: Jianhua Chen, Jie Wu, Yong Luo and Nanqu Huang
    Citation: European Journal of Medical Research 2022 27:281
  28. Hepatic resection is a potentially curative treatment for patients with hepatocellular carcinoma (HCC). The treatment of elderly patients with HCC has always been difficult. With the development of geriatrics ...

    Authors: Lining Xu, Yingying Xu, Guiping Li and Bo Yang
    Citation: European Journal of Medical Research 2022 27:280
  29. Hospitalized patients with non-severe community-acquired pneumonia (CAP) are treated with a β-lactam plus either a macrolide or doxycycline. Limited data exist on the effectiveness of the latter combination. T...

    Authors: Raghad K. Aldhahri, Shahad G. Gabb, Ohoud A. Shoaib, Reem M. Almadani, Khalid Eljaaly and Abrar K. Thabit
    Citation: European Journal of Medical Research 2022 27:279
  30. Most of hepatocellular carcinoma (HCC) arises on the background of chronic inflammation. The presence of infiltrating inflammatory cells is associated with tumour initiation, progression and clinical response ...

    Authors: Guo-Qiang Pan, Chun-Cheng Yang, Xiao-ling Shang, Zhao-Ru Dong and Tao Li
    Citation: European Journal of Medical Research 2022 27:278
  31. Preoperative evaluation of microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) is important for surgical strategy determination. We aimed to develop and establish a preoperative predic...

    Authors: Yijie Hao, Qingxia Yang, Qiye He, Huanjing Hu, Zongpeng Weng, Zhixi Su, Shuling Chen, Sui Peng, Ming Kuang, Zhihang Chen and Lixia Xu
    Citation: European Journal of Medical Research 2022 27:276
  32. Heme oxygenase one (HO-1) is considered a poor prognostic factor for survival in patients with severe-to-critical coronavirus disease (COVID-19), but the clinical correlation between heme catabolism biomarkers...

    Authors: Hsin-Yi Chen, I-Shiang Tzeng, Kuo-Wang Tsai, Yao-Kuang Wu, Ching-Feng Cheng, Kuo-Cheng Lu, Hsueh-Wen Chung, You-Chen Chao and Wen-Lin Su
    Citation: European Journal of Medical Research 2022 27:275
  33. The combined application of blue dye and radioisotopes is currently the primary mapping technique used for sentinel lymph node biopsy (SLNB) in breast cancer patients. However, radiocolloid techniques have not...

    Authors: Baiye Wang, Caifeng Ou, Jingang Yu, Jianping Ye, Yunfeng Luo, Yu Wang and Pusheng Zhang
    Citation: European Journal of Medical Research 2022 27:274
  34. Increasing evidence suggests that glucagon-like peptide 1 (GLP-1) receptor agonists (RA) can stabilize glycemic variability (GV) and interfere with eating behavior. This study compared the impact of insulin, G...

    Authors: Yi-Hsuan Lin, Chia-Hung Lin, Yu-Yao Huang, Hsin-Yun Chen, An-Shun Tai, Shih-Chen Fu, Sheng-Hwu Hsieh, Jui-Hung Sun, Szu-Tah Chen and Sheng-Hsuan Lin
    Citation: European Journal of Medical Research 2022 27:273
  35. Distant metastasis, which occurs at a rate of 25% in patients with esophageal cancer (EC), has a poor prognosis, with previous studies reporting an overall survival of only 3–10 months. However, few studies ha...

    Authors: Chao Zhu, Fengchun Mu, Songping Wang, Qingtao Qiu, Shuai Wang and Linlin Wang
    Citation: European Journal of Medical Research 2022 27:272
  36. Breast cancer is a worldwide health concern, and surgical removal has remained the preferred therapeutic option in most patients. Furthermore, the current study was designed to investigate the disease-free sur...

    Authors: Mohammad Yasin Karami, Laleh Dehghanpisheh, Ali Karami, Zahra Sabzloun, Hamid Reza Niazkar, Najmeh Mojarad, Ashkan Panah, Abdolrasoul Talei and Sedigheh Tahmasebi
    Citation: European Journal of Medical Research 2022 27:271
  37. The surgical treatment of inferior patellar pole fractures can be a challenge, especially in geriatric patients, who are particularly frequently affected by osteoporosis. The objective of this biomechanical st...

    Authors: Jana Seggewiss, Luis Fernando Nicolini, Philipp Lichte, Johannes Greven, Marx Ribeiro, Andreas Prescher, Roman Michalik, Christian Herren, Philipp Kobbe, Frank Hildebrand and Miguel Pishnamaz
    Citation: European Journal of Medical Research 2022 27:270
  38. The management of acute respiratory failure during pregnancy is a poorly defined issue in the literature, especially regarding the use of the prone position and the appropriate time for delivery. This study de...

    Authors: Rodrigo Nacif Barbosa, Maria Aparecida Braga, Bárbara Braga Costa and Frederico José Amedee Peret
    Citation: European Journal of Medical Research 2022 27:269
  39. Leptospirosis is an emerging neglected zoonotic disease that presents with nonspecific signs/symptoms and it can be mistaken for other diseases. Owing to limited diagnostic capacity and unawareness, the data o...

    Authors: Derick Hope, Stephen Businge, Stella Kyoyagala and Joel Bazira
    Citation: European Journal of Medical Research 2022 27:268
  40. Osteoporosis is characterized by deterioration of bone microarchitecture and reduced bone mass and can increase the risk of fracture. To reduce this risk, the aim of this study was to compare the combination e...

    Authors: Dalia M. Badary, Heba A. Galal, Mahmoud H. Abdelraheim, Mohamed I. Sedeek, Nesma M. Mohamed, Zakaria Y. Abd Elmageed and Magda M. Y. Farrag
    Citation: European Journal of Medical Research 2022 27:267
  41. Massage is widely used as a traditional technique during labor and delivery. The aim of this study was to evaluate the effect of Swedish massage with and without chamomile oil on delivery outcomes.

    Authors: Fatemeh Eskandari, Parvaneh Mousavi, Mahboubeh Valiani, Saeed Ghanbari and Mina Iravani
    Citation: European Journal of Medical Research 2022 27:266
  42. Helical TomoTherapy® is widely used for total body irradiation as a component of conditioning regimens before allogeneic bone-marrow transplantation. However, this technique limits the maximum length of a plannin...

    Authors: Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Thomas Müdder, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Leonard C. Schmeel and Frank A. Giordano
    Citation: European Journal of Medical Research 2022 27:265
  43. Hepatic encephalopathy (HE) is a reversible syndrome of brain dysfunction caused by advanced liver disease. Weighted gene co-expression network analysis (WGCNA) could establish a robust co-expression network t...

    Authors: Chihao Zhang, Guqing Luo, Jiayun Lin, Zhifeng Zhao, Meng Luo and Hongjie Li
    Citation: European Journal of Medical Research 2022 27:264
  44. The poor prognosis of cervical spine surgery is mainly manifested as poor neurological recovery and the presence of new upper extremity dysfunction that promotes significant psychological and physiological bur...

    Authors: Peng Wang, Baoge Liu, Tianhua Rong and Bingxuan Wu
    Citation: European Journal of Medical Research 2022 27:263

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