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  1. Content type: Review

    The stem cell as the building block necessary for tissue reparation and homeostasis plays a major role in regenerative medicine. Their unique property of being pluripotent, able to control immune process and e...

    Authors: Felix Dyrna, Elmar Herbst, Alexander Hoberman, Andreas B. Imhoff and Andreas Schmitt

    Citation: European Journal of Medical Research 2016 21:29

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  2. Content type: Research

    Studies have been reported that cyclin-dependent kinase5 (CDK5) was associated with the development of several cancers. However, the relationship between CDK5 level and clinicopathological factors is still poo...

    Authors: Deng-Hua Pan, Mei-Lin Zhu, Xiao-Miao Lin, Xing-Gu Lin, Rong-Quan He, Yan-Xin Ling, Shi-Tao Su, Madushi Mihiranganee Wickramaarachchi, Yi-Wu Dang, Kang-Lai Wei and Gang Chen

    Citation: European Journal of Medical Research 2016 21:28

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  3. Content type: Research

    Tarsoconjunctival flap advancement, or the Hughes procedure, is among the techniques of choice for reconstructing full-thickness lower eyelid defects so as to restore normal anatomy and function with the best ...

    Authors: Ahmed M. Hishmi, Konrad R. Koch, Mario Matthaei, Edwin Bölke, Claus Cursiefen and Ludwig M. Heindl

    Citation: European Journal of Medical Research 2016 21:27

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  4. Content type: Research

    Histone deacetylation, a common hallmark in malignant tumors, strongly alters the transcription of genes involved in the control of proliferation, cell survival, differentiation and genetic stability. We have ...

    Authors: Reena Buurman, Maria Sandbothe, Brigitte Schlegelberger and Britta Skawran

    Citation: European Journal of Medical Research 2016 21:26

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  5. Content type: Review

    Neoadjuvant radio chemotherapy and immediate reconstruction for breast cancer are still under debate. But there are recent abstracts and articles which show that neoadjuvant radio chemotherapy is feasible and ...

    Authors: Carolin Nestle-Krämling, Edwin Bölke, Wilfried Budach and Christoph Andree

    Citation: European Journal of Medical Research 2016 21:24

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    The Erratum to this article has been published in European Journal of Medical Research 2016 21:30

  6. Content type: Research

    It has been previously postulated that high phenylalanine (Phe) might disturb intracerebral dopamine production, which is the main regulator of prolactin secretion in the pituitary gland. Previously, various a...

    Authors: Eszter Juhász, Erika Kiss, Erika Simonova, Attila Patócs and Peter Reismann

    Citation: European Journal of Medical Research 2016 21:22

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  7. Content type: Review

    Despite substantial advances in the imaging techniques and pathophysiological understanding over the last decades, identification of the underlying causes of left ventricular hypertrophy by means of echocardio...

    Authors: Dan Liu, Kai Hu, Peter Nordbeck, Georg Ertl, Stefan Störk and Frank Weidemann

    Citation: European Journal of Medical Research 2016 21:21

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  8. Content type: Research

    Pulmonary cavitation is the classic hallmark of pulmonary tuberculosis (PTB) and is the site of very high mycobacterial burden associated with antimycobacterial drug resistance and treatment failure. The objec...

    Authors: Qiusheng Huang, Yongmei Yin, Shougang Kuai, Yan Yan, Jun Liu, YingYing Zhang, Zhongbao Shan, Lan Gu, Hao Pei and Jun Wang

    Citation: European Journal of Medical Research 2016 21:20

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  9. Content type: Case report

    Pierson syndrome (PS) is a rare autosomal recessive disorder, caused by mutations in the laminin β2 (LAMB2) gene. It is characterized by congenital nephrotic syndrome, microcoria, and neurodevelopmental defici...

    Authors: Boutaina Zemrani, François Cachat, Olivier Bonny, Eric Giannoni, Jacques Durig, Florence Fellmann and Hassib Chehade

    Citation: European Journal of Medical Research 2016 21:19

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  10. Content type: Research

    To assess clinical application of computed tomography (CT)-guided 125I seed implantation for patients who cannot endure or unwillingly receive repeated surgery, chemotherapy, or radiotherapy for unmanageable cerv...

    Authors: Hai Huang, Shaonian Xu, Fusheng Li, Zhenguang Du and Liang Wang

    Citation: European Journal of Medical Research 2016 21:18

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  11. Content type: Research

    Lung cancer is one of the most preventable causes of death globally both in developed and developing countries. Although it is well established that smokers develop lung cancer, there are some smokers who are ...

    Authors: Vidyullatha Peddireddy, Siva Prasad Badabagni, Sandhya Devi Gundimeda, Vasudha Mamidipudi, Pardhanandana Reddy Penagaluru and Hema Prasad Mundluru

    Citation: European Journal of Medical Research 2016 21:17

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  12. Content type: Research

    Hepatitis, a highly contagious viral infection, is one of the leading killer diseases globally caused by hepatitis virus. Among the existing viral causes for hepatic failure, hepatitis B virus (HBV) plays a si...

    Authors: Zelalem Desalegn, Liya Wassie, Habtamu Bedimo Beyene, Adane Mihret and Yehenew A. Ebstie

    Citation: European Journal of Medical Research 2016 21:16

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  13. Content type: Research

    Isolated radial neck fractures occur only in rare cases. The majority of cases are non-displaced or minimally displaced and can be treated conservatively. Conservative treatment, however, might result in secon...

    Authors: G. H. Sandmann, M. Crönlein, M. Neumaier, M. Beirer, A. Buchholz, U. Stöckle, P. Biberthaler and S. Siebenlist

    Citation: European Journal of Medical Research 2016 21:15

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  14. Content type: Review

    Vitamin D has immuno-modulatory properties, and deficient levels of circulating 25-hydroxyvitamin D (<30 nmol/l) may contribute to increased risk of infectious illnesses. This narrative review summarises data ...

    Authors: Armin Zittermann, Stefan Pilz, Harald Hoffmann and Winfried März

    Citation: European Journal of Medical Research 2016 21:14

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  15. Content type: Research

    Overlengthening by radial head prosthetic replacement leads to insufficient functionality and increased capitellar wear. It has been shown that in monopolar prostheses, the radial overlengthening by an overstu...

    Authors: Kilian Wegmann, Wei Zhang, Volker Strauss, Christian Ries, Lars P. Müller and Klaus J. Burkhart

    Citation: European Journal of Medical Research 2016 21:12

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  16. Content type: Research

    To analyse the timing of cardiac troponin (cTn) measurements in high-risk and cTn-positive acute coronary syndromes without persistent ST-segment elevation (NSTE-ACS) in two structurally different German chest...

    Authors: Dieter Fischer, Friederike Remberg, Dirk Böse, Michael Lichtenberg, Philipp Kümpers, Pia Lebiedz, Hermann-Joseph Pavenstädt, Johannes Waltenberger and Frank Breuckmann

    Citation: European Journal of Medical Research 2016 21:11

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  17. Content type: Research

    Pathological examination combined with tumor markers has become a standard for the diagnosis of intracranial germ cell tumors (ICGCTs), but the current concept of ‘secreting germ cell tumors’ and three empiric...

    Authors: Mingming Hu, Hongzhi Guan, Ching C. Lau, Keita Terashima, Zimeng Jin, Liying Cui, Yuzhou Wang, Guilin Li, Yong Yao, Yi Guo, Yan Michael Li, Dingrong Zhong, Juan Xiao, Xirun Wan, Xin Lian, Feng Feng…

    Citation: European Journal of Medical Research 2016 21:10

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  18. Content type: Research

    Diaphragm motion during spontaneous or mechanical respiration hinders image-guided percutaneous interventions of tumours in lung and upper abdomen. Motion-tracking methods can be applied but increase procedure...

    Authors: Thomas Günther Lesser, Harald Schubert, Daniel Güllmar, Jürgen R. Reichenbach and Frank Wolfram

    Citation: European Journal of Medical Research 2016 21:9

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  19. Content type: Research

    The rabbit disc model is useful for the study of intervertebral disc (IVD) degeneration and experimental therapeutic interventions. The annulotomy-induced disc models present several drawbacks, particularly an...

    Authors: Long Xin, Chun Zhang, Fuhua Zhong, Shunwu Fan, Wei Wang and Zhenbin Wang

    Citation: European Journal of Medical Research 2016 21:7

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  20. Content type: Review

    Over the past 60 years, hyaluronidase has been successfully utilized in ophthalmic surgery and is now being implemented in dermatosurgery as well as in other surgical disciplines. The enzyme is considered a “s...

    Authors: Bettina Alexandra Buhren, Holger Schrumpf, Norman-Philipp Hoff, Edwin Bölke, Said Hilton and Peter Arne Gerber

    Citation: European Journal of Medical Research 2016 21:5

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  21. Content type: Research

    Laparoscopic Surgery has become a worldwide standard procedure for a variety of indications. This has been attributed to a milder postoperative inflammatory response by the innate immune system potentially med...

    Authors: Philipp Lingohr, Jonas Dohmen, Hanno Matthaei, Nils Konieczny, Juliane Hoffmann, Edwin Bölke, Sven Wehner and Jörg C. Kalff

    Citation: European Journal of Medical Research 2016 21:4

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  22. Content type: Research

    Focal colorectal uptake in 18FDG-PET/CT may be associated with a malignancy and can be quantified. This provides the basis for an automatic trigger threshold above which cases are flagged for colonoscopic evaluat...

    Authors: Wolfgang Luboldt, Baerbel Wiedemann, Sebastian Fischer, Boris Bodelle, Hans Joachim Luboldt, Frank Grünwald and Thomas J. Vogl

    Citation: European Journal of Medical Research 2016 21:2

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  23. Content type: Research

    The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2).

    Authors: Robert Rozenberg, Robert T. Mankowski, Luc J. C. van Loon, Janneke G. Langendonk, Eric J. G. Sijbrands, Anton H. van den Meiracker, Henk J. Stam and Stephan F. E. Praet

    Citation: European Journal of Medical Research 2016 21:1

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  24. Content type: Research

    Diagnosis and treatment of stress fractures still remains to be a clinical and radiological challenge. Therapeutic options vary from conservative treatment to surgical treatment without a clear treatment conce...

    Authors: Moritz Crönlein, Isabel Rauscher, Ambros J. Beer, Markus Schwaiger, Christoph Schäffeler, Marc Beirer, Stephan Huber, Gunther H. Sandmann, Peter Biberthaler, Matthias Eiber and Chlodwig Kirchhoff

    Citation: European Journal of Medical Research 2015 20:99

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  25. Content type: Research

    Interleukin 17 (IL-17) is a proinflammatory cytokine produced by a new subset of activated CD4+ T cells, Th17 cells. We previously showed that increased Th17 cell populations were presented in human medullobla...

    Authors: Ping Zhou, Qilin Zhang, Yao Zhao, Hongying Sha, Xiaoyun Cao and Yongfei Wang

    Citation: European Journal of Medical Research 2015 20:98

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  26. Content type: Case report

    Adenoid cystic carcinoma (ACC) is a rare malignant tumor that might occur in nasal cavity and paranasal sinuses. It is characteristic for poor prognosis, especially the solid histopathological subtype of the t...

    Authors: Piotr Wardas, Michał Tymowski, Agnieszka Piotrowska-Seweryn, Wojciech Kaspera, Aleksandra Ślaska-Kaspera and Jarosław Markowski

    Citation: European Journal of Medical Research 2015 20:97

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  27. Content type: Research

    There are two major theories describing the pathophysiology of migraines. Vascular theory explains that migraines resulted from vasodilation of meningeal vessels irritating the trigeminal nerves and causing pa...

    Authors: Ahmadreza Pourshoghi, Arash Danesh, David Stuart Tabby, John Grothusen and Kambiz Pourrezaei

    Citation: European Journal of Medical Research 2015 20:96

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  28. Content type: Research

    Colon cancer is a frequently occurring primary malignant tumor. Chemotherapy can reduce the risk of local and distant relapse. Therefore, it is very important to find new biomarkers that can predict chemoresis...

    Authors: Jinsong Hu, Ye Xu and Sanjun Cai

    Citation: European Journal of Medical Research 2015 20:95

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  29. Content type: Case report

    Male breast carcinoma (MBC) is rarely encountered in clinical practice. Due to its paucity, our knowledge of MBC only rely on small or single-institutional studies and sporadic cases. The current guidelines fo...

    Authors: Min Liu, Qiang Wang, Bin Liu, Ling Gao, Di Wu, Shuo Yang, Bailong Liu and Lihua Dong

    Citation: European Journal of Medical Research 2015 20:94

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  30. Content type: Research

    The purpose of the present study was to investigate the influence of the pronator quadratus (PQ) muscle repair following volar plate fixation of distal radius fractures with special regards to the forearm pron...

    Authors: Sandra Häberle, Gunther Hubertus Sandmann, Stephan Deiler, Tobias Maximilian Kraus, Florian Fensky, Tobias Torsiglieri, Ina-Christine Rondak, Peter Biberthaler, Ulrich Stöckle and Sebastian Siebenlist

    Citation: European Journal of Medical Research 2015 20:93

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  31. Content type: Research

    To evaluate the clinical value of plain magnetic resonance (MR) imaging (including magnetic resonance cholangiopancreatography, MRCP) and coronal liver acquisition with volume acceleration (LAVA) technique in ...

    Authors: Nana Sun, Qing Xu, Xisheng Liu, Wei Liu and Jianwei Wang

    Citation: European Journal of Medical Research 2015 20:92

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  32. Content type: Case report

    Placenta accreta is a rare obstetric condition but can lead to life-threatening complications that was mainly diagnosed in the third trimester. We present a case of acute trophoblastic pulmonary embolism (PE) ...

    Authors: Qiu-ming Wang, Hui-li Liu and Qun Dang

    Citation: European Journal of Medical Research 2015 20:91

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  33. Content type: Research

    The present study aims to evaluate the relationship between physical activity and sexual dysfunction amongst an ethnic South Asian population living in the United Kingdom and compare the association with that ...

    Authors: Lasantha S. Malavige, Pabasi Wijesekara, Priyanga Ranasinghe and Jonathan C. Levy

    Citation: European Journal of Medical Research 2015 20:90

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  34. Content type: Research

    Glucosamine is widely used to improve the symptoms and to delay the structural progression of osteoarthritis. However, its efficacy in osteoarthritis has been controversial and its underlying mechanism of acti...

    Authors: Yeon-Ho Kang, Sujeong Park, Chihyun Ahn, Jinsoo Song, Dongkyun Kim and Eun-Jung Jin

    Citation: European Journal of Medical Research 2015 20:89

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    The Erratum to this article has been published in European Journal of Medical Research 2016 21:3

  35. Content type: Research

    Avulsion fractures of the tibial insertion of the posterior cruciate ligament (PCL) have always been regarded as rare injuries. The tibial attachment of the PCL is located in an area, which is difficult to acc...

    Authors: Wei Huang, Xuan Gong, Mishra Rahul, Shukla Priyanka, Changdong Wang, Xi Liang, Guoliang Ding and Ning Hu

    Citation: European Journal of Medical Research 2015 20:88

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  36. Content type: Case report

    Tension-band wiring (TBW) is a well-established fixation technique for two-part, transverse fracture types of the olecranon. However, complication rates up to 80 % are reported. By reporting on the enormous im...

    Authors: Lukas Willinger, Martin Lucke, Moritz Crönlein, Gunther H. Sandmann, Peter Biberthaler and Sebastian Siebenlist

    Citation: European Journal of Medical Research 2015 20:87

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  37. Content type: Research

    Focal nodular hyperplasia (FNH) are benign lesions in the liver. Although liver resection is generally not indicated in these patients, rare indications for surgical approaches indeed exist. We here report on ...

    Authors: Hans Michael Hau, Georgi Atanasov, Hans-Michael Tautenhahn, Rudolf Ascherl, Georg Wiltberger, Markus Bo Schoenberg, Mehmet Haluk Morgül, Dirk Uhlmann, Michael Moche, Jochen Fuchs, Moritz Schmelzle and Michael Bartels

    Citation: European Journal of Medical Research 2015 20:86

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  38. Content type: Research

    Germline mutations in PALB2 gene make a small contribution to heritable breast cancer susceptibility. A recent report has revealed that women with mutations in the PALB2 gene were more than nine times as like...

    Authors: Yong Tao Li, Wei Hua Jiang, Xiao Wen Wang, Ming Shuai Zhang, Cheng Guang Zhang, Li Na Yi, Fulati WuwaliKhan, Aisikaer Ayoufu and Jiang Hua Ou

    Citation: European Journal of Medical Research 2015 20:85

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  39. Content type: Research

    Sepsis, systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) remain the most frequent causes of complications and death in severely injured patients. A main reason for ...

    Authors: Helen Vester, P. Dargatz, S. Huber-Wagner, P. Biberthaler and M. van Griensven

    Citation: European Journal of Medical Research 2015 20:84

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  40. Content type: Research

    Locking plate fixation of displaced fractures of the proximal humerus is still accompanied by a distinct complication rate, especially in case of osteoporotic bone, short-segment fracture length and comminutio...

    Authors: Marc Beirer, Moritz Crönlein, Arne J. Venjakob, Tim Saier, Marcus Schmitt-Sody, Stefan Huber-Wagner, Peter Biberthaler and Chlodwig Kirchhoff

    Citation: European Journal of Medical Research 2015 20:82

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