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  1. The androgen receptor (AR) has been demonstrated to play a role in the pathogenesis of glioblastoma; however, the implications of circulating testosterone levels in the biology of glioblastoma remain unknown.

    Authors: Helga Fariña-Jerónimo, Rita Martín-Ramírez, Rebeca González-Fernández, Lilian Medina, Antonia de Vera, Pablo Martín-Vasallo and Julio Plata-Bello
    Citation: European Journal of Medical Research 2024 29:57
  2. Patients with autoimmune and immune-mediated diseases (AI-IMD) are at greater risk of COVID-19 infection; therefore, they should be prioritized in vaccination programs. However, there are concerns regarding th...

    Authors: Mahya Shabani, Parnian Shobeiri, Shadi Nouri, Zahra Moradi, Robel Assefa Amenu, Mohammad-Mehdi Mehrabi Nejad and Nima Rezaei
    Citation: European Journal of Medical Research 2024 29:55
  3. To screen characteristic genes related to sarcopenia by bioinformatics and machine learning, and to verify the accuracy of characteristic genes in the diagnosis of sarcopenia. Download myopia-related data sets...

    Authors: Yong Chen, Zhenyu Zhang, Xiaolan Hu and Yang Zhang
    Citation: European Journal of Medical Research 2024 29:54
  4. Previous compelling evidence suggests an association between Type 2 diabetes (T2D) and neurodegenerative diseases. However, it remains uncertain whether Type 1 diabetes mellitus (T1DM) exerts a causal influenc...

    Authors: Chaofan Geng, Ke Meng, Bo Zhao, Xiaoduo Liu and Yi Tang
    Citation: European Journal of Medical Research 2024 29:53
  5. Bladder cancer is an epidemic and life-threating urologic carcinoma. Anoikis is a unusual type of programmed cell death which plays a vital role in tumor survival, invasion and metastasis. Nevertheless, the re...

    Authors: Haoran Wang, Jianyong Liu, Runhua Tang, Jie Hu, Ming Liu, Jianye Wang, Jingwen Zhang and Huimin Hou
    Citation: European Journal of Medical Research 2024 29:52
  6. Glial fibrillary acidic protein (GFAP), an intracellular type III intermediate filament protein, provides structural support and maintains the mechanical integrity of astrocytes. It is predominantly found in t...

    Authors: Xiaoxiao Zheng, Jingyao Yang, Yiwei Hou, Xinye Shi and Kangding Liu
    Citation: European Journal of Medical Research 2024 29:51
  7. Stroke is the second leading cause of death worldwide, and observational studies have suggested a correlation between antioxidants and reduced stroke risk. However, it remains unclear whether causal relationsh...

    Authors: Rundong Chen, Hanchen Liu, Guanghao Zhang, Qian Zhang, Weilong Hua, Lei Zhang, Nan Lv, Yilei Zhang, Dongwei Dai, Rui Zhao, Qiang Li, Qinghai Huang, Yi Xu, Pengfei Yang, Jianmin Liu and Qiao Zuo
    Citation: European Journal of Medical Research 2024 29:50
  8. Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that target the endocannabinoid system in many body organs. SCs can initiate pathophysiological changes in many tissues which c...

    Authors: Ayman Alzu’bi, Fatimah Almahasneh, Ramada Khasawneh, Ejlal Abu-El-Rub, Worood Bani Baker and Raed M. Al-Zoubi
    Citation: European Journal of Medical Research 2024 29:49
  9. This study was designed to clarify the function and potential mechanism of gentiopicroside (GPS) in regulating the malignant progression of gastric cancer (GC) through in vitro cellular experiments and in vivo...

    Authors: Qishuai Chen, Tongtong Zhang, Bingjun Li, Zhenguo Zhu, Xiaomin Ma, Yun Zhang, Linchuan Li, Jiankang Zhu and Guangyong Zhang
    Citation: European Journal of Medical Research 2024 29:47
  10. Caring for hemodialysis patients could be a heavy burden on family caregivers, causing them to become fatigued and decrease their quality of life. This study aimed to investigate whether Jacobson’s relaxation ...

    Authors: Seyedeh Azam Sajadi, Farzaneh Ravash and Zahra Farsi
    Citation: European Journal of Medical Research 2024 29:46
  11. There are more than 170 subtypes of sarcomas (SARC), which pose a challenge for diagnosis and patient management. Relatively simple or complex karyotypes play an indispensable role in the early diagnosis and e...

    Authors: Jianlong Wang, Guowei Wang, Tianrui Hu, Hongyi Wang and Yong Zhou
    Citation: European Journal of Medical Research 2024 29:45
  12. Post-traumatic stress disorder (PTSD), a disease state that has an unclear pathogenesis, imposes a substantial burden on individuals and society. Traumatic brain injury (TBI) is one of the most significant tri...

    Authors: Peng Qi, Mengjie Huang, Xuewen Ren, Yongzhi Zhai, Chen Qiu and Haiyan Zhu
    Citation: European Journal of Medical Research 2024 29:44
  13. Epilepsy, a central neurological disorder, has a complex genetic architecture. There is some evidence suggesting that genetic factors play a role in both the occurrence of epilepsy and its treatment. However, ...

    Authors: Shitao Wang, Zhenrong Xie, Tian Jun, Xuelu Ma, Mengen Zhang, Feng Rao, Hui Xu, Jinghong Lu, Xiangqian Ding and Zongyou Li
    Citation: European Journal of Medical Research 2024 29:43
  14. The established therapy of asthma might be supported by additional non-pharmaceutical measures, such as the Buteyko breathing technique (BBT); however, the available data are mixed. To clarify the effects of B...

    Authors: Katrin Vagedes, Silja Kuderer, Rainer Ehmann, Matthias Kohl, Johannes Wildhaber, Rudolf A. Jörres and Jan Vagedes
    Citation: European Journal of Medical Research 2024 29:42
  15. Diabetes mellitus in pregnancies is associated with adverse outcomes both for the mothers and babies. Postponing pregnancy in unoptimized conditions and stabilisation of glucose should be prioritized. This sco...

    Authors: Sarah Awang Dahlan, Idayu Badilla Idris, Azmawati Mohammed Nawi and Rahana Abd Rahman
    Citation: European Journal of Medical Research 2024 29:41
  16. Whether symptomatic unruptured intracranial aneurysms (UIAs) lead to change in circulating inflammation remains unclear. This study aims to evaluate the role of hematological inflammatory indicators in predict...

    Authors: De-Xiang Zheng, Yi-Yang Lv, Xiao-Jing Zhang, Jie-Shun Ye, Jian-Xing Zhang, Cha Chen, Bin Luo and Dan Yan
    Citation: European Journal of Medical Research 2024 29:40
  17. Exosomes released from decidual stromal cells (DSC-exos) play a crucial role in facilitating the epithelial–mesenchymal transition (EMT) of trophoblasts and insufficient trophoblasts EMT are associated with UR...

    Authors: Miao Xiong, Qiaohong Wang, Xiaoxin Zhang, Liping Wen and Aimin Zhao
    Citation: European Journal of Medical Research 2024 29:39
  18. The senescence-associated secretory phenotype (SASP) is a generic term for the secretion of cytokines, such as pro-inflammatory factors and proteases. It is a crucial feature of senescent cells. SASP factors i...

    Authors: Shangkun Zhao, Zhi Qiao, Roman Pfeifer, Hans-Christoph Pape, Keya Mao, Hai Tang, Bin Meng, Songfeng Chen and Hongjian Liu
    Citation: European Journal of Medical Research 2024 29:38
  19. The phenotype of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) patients is determined by the type of DMD gene variation, its location, effect on reading frame, and its size. The primary ob...

    Authors: Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Roshan Liyanage, Dhammika Amaratunga, Yetrib Hathout, Harry W. M. Steinbusch, Ashwin Dalal, Eric P. Hoffman and K. Ranil D. de Silva
    Citation: European Journal of Medical Research 2024 29:37
  20. There is a paucity of data on patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) and a decompensated diabetic state, diabetic ketoacidosis (DKA). Therefore, we aimed to investig...

    Authors: Asif Ullah, Umar Khan, Shumaila Asif, Hafiz Muhammad Shafique, Talha Sajid, Jateesh Kumar, Waheed Akhtar, Syed Muhammad Jawad Zaidi, Jahanzeb Malik and Amin Mehmoodi
    Citation: European Journal of Medical Research 2024 29:36
  21. Breast cancer (BC) is one of the most common malignancies in women and the leading cause of cancer-related death in women. The newly emerged non-coding RNAs tsRNAs (tRNA-derived small RNAs) play an important r...

    Authors: Lu-Jue Gao, Si-Xun Zhu, Ying-Yi Wei, Hua-Wei Meng, Jing Gu, Hao Zhang and Li-Juan Dai
    Citation: European Journal of Medical Research 2024 29:35
  22. Systemic lupus erythematosus (SLE) is a common autoimmune disease that impacts various organs. Lupus nephritis (LN) significantly contributes to death in children with SLE. Toll-like receptor (TLR) adaptor int...

    Authors: Jin-Wen Xu, Ming-Yan Wang, Yan Mao, Zheng-Yun Hu, Xiao-Lin Miao, Feng Jiang and Guo-Ping Zhou
    Citation: European Journal of Medical Research 2024 29:34
  23. Body temperature (BT) is routinely measured and can be controlled in critical care settings. BT can impact patient outcome, but the relationship between BT and mortality has not been well-established.

    Authors: Daniel J. Tan, Jiayang Chen, Yirui Zhou, Jaryl Shen Quan Ong, Richmond Jing Xuan Sin, Thach V. Bui, Anokhi Amit Mehta, Mengling Feng and Kay Choong See
    Citation: European Journal of Medical Research 2024 29:33
  24. Transthyretin amyloid cardiomyopathy (ATTR-CM), characterized by the extracellular deposition of an insoluble amyloid protein in the heart, is one of the main causes of heart failure in elderly patients. In th...

    Authors: Aiganym Imakhanova, Reiko Ideguchi, Hiroaki Kawano, Koji Maemura and Takashi Kudo
    Citation: European Journal of Medical Research 2024 29:32
  25. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive deterioration of upper and lower motor neurons. A definitive diagnostic test or biomarker for ALS is currently u...

    Authors: Kateřina Klíčová, Jan Mareš, Kateřina Menšíková, Michaela Kaiserová, David Friedecký, Petr Kaňovský, Miroslav Strnad and Radoslav Matěj
    Citation: European Journal of Medical Research 2024 29:31
  26. BRCA2-mutated carriers have a high lifetime risk of breast cancer (BC), an early age of onset, and an increased risk of other cancers (including ovarian, pancreatic, and prostate cancer). Almost 70–80% of BRCA2-m...

    Authors: Pu-Chun Li, Yi-Fan Zhu, Wen-Ming Cao and Bei Li
    Citation: European Journal of Medical Research 2024 29:30
  27. Ewing sarcoma (EWS) is a malignancy which primarily arises in adolescence and has been studied extensively in this population. Much less is known about the rare patient cohort over the age of 40 at diagnosis. ...

    Authors: Marco Braaten, Jacob Braaten, Jasleen Chaddha, Robert Hu, Connor Lanoue, Peter Silberstein, Abubakar Tauseef, Noureen Asghar and Mohsin Mirza
    Citation: European Journal of Medical Research 2024 29:29
  28. This study aims to assess the sustained immunological response to the SARS-CoV-2 vaccine in patients with autoimmune inflammatory rheumatic diseases (AIRD) undergoing different treatment regimens.

    Authors: Silvia Garcia-Cirera, Joan Calvet, Juan Francisco Delgado de la Poza, Antoni Berenguer-Llergo, Cristóbal Orellana, Menna Rusiñol, Maria Llop, Marta Arévalo, Alba Garcia-Pinilla, Ester Costa, Cristina Aymerich, Rafael Gómez, Anna Carreras and Jordi Gratacós
    Citation: European Journal of Medical Research 2024 29:28
  29. During the COVID-19 pandemic, some populations, including immunocompromised patients, could not tolerate COVID-19 vaccination or had low responses. Evusheld is a combined neutralizing monoclonal antibody conta...

    Authors: Shaymaa Glhoom, Aya Fergany, Dina El-Araby, Asmaa A. Abdelkhalek, Asmaa Gomaa, Eman O. Zayed and Mohamed Abd-ElGwad
    Citation: European Journal of Medical Research 2024 29:27
  30. This review article explores the dynamic field of radiopharmaceuticals, where innovative developments arise from combining radioisotopes and pharmaceuticals, opening up exciting therapeutic possibilities. The ...

    Authors: Shivang Dhoundiyal, Shriyansh Srivastava, Sachin Kumar, Gaaminepreet Singh, Sumel Ashique, Radheshyam Pal, Neeraj Mishra and Farzad Taghizadeh-Hesary
    Citation: European Journal of Medical Research 2024 29:26
  31. Using the particular nature of melanoma mutanomes to develop medicines that activate the immune system against specific mutations is a game changer in immunotherapy individualisation. It offers a viable soluti...

    Authors: Farida Zakariya, Fatma K. Salem, Abdulwhhab Abu Alamrain, Vivek Sanker, Zainab G. Abdelazeem, Mohamed Hosameldin, Joecelyn Kirani Tan, Rachel Howard, Helen Huang and Wireko Andrew Awuah
    Citation: European Journal of Medical Research 2024 29:25
  32. Perioperative pediatric mortality is significantly higher in low-resource countries due to a scarcity of well-trained professionals and a lack of well-equipped pediatric perioperative services. There has been ...

    Authors: Misganew Terefe Molla, Nebiyu Shitaye Anley, Bekalu Wubshet Zewdie, Amanuel Sisay Endeshaw and Fantahun Tarekegn Kumie
    Citation: European Journal of Medical Research 2024 29:24
  33. Previous studies have found that frailty and sarcopenia are commonly diagnosed in inflammatory bowel disease (IBD) patients, indicating an association between these conditions. Nonetheless, the cause‒effect co...

    Authors: Peng Wang, Wei Tao, Zhiqiang Zhang, Cong Xu, Yuan Qiu and Weidong Xiao
    Citation: European Journal of Medical Research 2024 29:23
  34. Clear cell renal cell carcinoma (ccRCC) is characterized as one of the most common types of urological cancer with high degrees of malignancy and mortality. Due to the limited effectiveness of existing traditi...

    Authors: Qinfan Yao, Xiuyuan Zhang, Yucheng Wang, Cuili Wang, Chunchun Wei, Jianghua Chen and Dajin Chen
    Citation: European Journal of Medical Research 2024 29:22
  35. Kidney disease is a progressive and irreversible condition in which immunity is a contributing factor that endangers human health. It is widely acknowledged that macrophages play a significant role in developi...

    Authors: Yixia Cao, Boyan Hu, Yunhe Fan, Wei Wang, Mingxuan Chi, Moussa Ide Nasser, Kuai Ma and Chi Liu
    Citation: European Journal of Medical Research 2024 29:21
  36. SLC10A3, a gene upregulated in pan-cancer, lacks full understanding regarding its prognostic implications and association with immune infiltration in colorectal cancer (CRC). This study comprehensively analyze...

    Authors: Bangting Wang, Wentao Fan, Yuwen Tao, Shijie Zhang, Jiankun Wang, Zhining Fan, Li Liu and Yan Wang
    Citation: European Journal of Medical Research 2024 29:20
  37. The biological behavior of low-grade glioma (LGG) is significantly affected by N6-methyladenosine (m6A) methylation, an essential epigenetic alteration. Therefore, it is crucial to create a prognostic model fo...

    Authors: Honggang Wu, Siqi Chen, Ziliang Hu, Rong Ge, Lu Ma, Chao You and Yi Huang
    Citation: European Journal of Medical Research 2024 29:19
  38. Pathogenesis of acute respiratory distress syndrome (ARDS) involves immune cell death and removal from the injured lungs. ARDS severity is related to lung compliance. However, the correlation between the respi...

    Authors: Shaw-Woei Leu, Chien-Min Chu, Chia-Jung Chung, Chih-Yu Huang, Chao-Hung Wang, Li-Fu Li and Huang-Pin Wu
    Citation: European Journal of Medical Research 2024 29:16
  39. Early diagnosis and pharmacological treatment of central nervous system (CNS) diseases has been a long-standing challenge for clinical research due to the presence of the blood–brain barrier. Specific proteins...

    Authors: Xiang-Min Zhang, Jie Huang, Xiao-Ying Ni, Hui-Ru Zhu, Zhong-Xin Huang, Shuang Ding, Xin-Yi Yang, Yan-Di Tan, Jian-Fu Chen and Jin-Hua Cai
    Citation: European Journal of Medical Research 2024 29:15
  40. The importance of protein tyrosine phosphatase non-receptor type 3 (PTPN3) in controlling multifaceted tumor cell behaviors throughout cancer development has received widespread attention. Nevertheless, little...

    Authors: Ziting Zhou, Zhengjun Lin, Mingrui Wang, Lifan Wang, Yuqiao Ji, Jing Yang, Yaocheng Yang, Guanghui Zhu and Tang Liu
    Citation: European Journal of Medical Research 2024 29:12
  41. Although simple renal cyst (SRC) is a kind of structural alterations of kidney with age, the relationship between SRC and renal function is still obscure. We investigated the relationship between SRC and renal...

    Authors: Cheng Jin, Lu Wei, Zhenzhu Yong, Yao Ma, Bei Zhu, Xiaohua Pei, Canhong Zhu and Weihong Zhao
    Citation: European Journal of Medical Research 2024 29:11
  42. Right-side aortic arch concomitant with Kommerell’s diverticulum (KD) is a rare and complex ailment, and there is no consensus on the optimal strategy to deal with this congenital anomaly. We retrospectively a...

    Authors: Yali Wang, Shuchun Li, Min Jin, Yunxing Xue, Dongjin Wang and Qing Zhou
    Citation: European Journal of Medical Research 2024 29:10
  43. The aim of this study was to evaluate the efficacy of fluorine 18 (18F) labeled fibroblast activation protein inhibitor (FAPI) in identifying mediastinal and hilar lymph node metastases and to develop a model to ...

    Authors: Yuyun Sun, Yun Sun, Zili Li, Shaoli Song, Kailiang Wu, Jingfang Mao and Jingyi Cheng
    Citation: European Journal of Medical Research 2024 29:9
  44. Shiitake mushrooms are a fungal food that has been recorded in Chinese medicine to nourish the blood and qi. Lentinan (lLNT) is an active substance extracted from shiitake mushrooms with powerful antioxidant, ...

    Authors: Guangda Zhou, Haiyan Liu, Ying Yuan, Qian Wang, Lanping Wang and Jianghua Wu
    Citation: European Journal of Medical Research 2024 29:8
  45. This study assessed the predictive value of electrical activity of the diaphragm (EAdi) and the EAdi-derived monitoring index in the prognosis of patients with severe cerebral hemorrhage.

    Authors: Lin Yao, Zihao Zhou, Tao Yu, Guiliang Wang, Zhen Fan and Yun Tang
    Citation: European Journal of Medical Research 2024 29:7
  46. Many studies have evaluated stroke using claims data; most of these studies have defined ischemic stroke using an operational definition following the rule-based method. Rule-based methods tend to overestimate...

    Authors: Hyunsun Lim, Youngmin Park, Jung Hwa Hong, Ki-Bong Yoo and Kwon-Duk Seo
    Citation: European Journal of Medical Research 2024 29:6
  47. Mechanical power (MP) is the total energy released into the entire respiratory system per minute which mainly comprises three components: elastic static power, Elastic dynamic power and resistive power. Howeve...

    Authors: Yongpeng Xie, Jiaxin Shi, Suxia Liu, Xiaobing Chen, Yanli Wang, Xiaomin Li and Yao Yan
    Citation: European Journal of Medical Research 2024 29:5
  48. Female fertility declines with increased maternal age, and this decline is even more rapid after the age of 35 years. Follicular fluid (FF) is a crucial microenvironment that plays a significant role in the de...

    Authors: Yanqiong Gu, Xunyi Zhang, Ruixue Wang, Yingying Wei, Hao Peng, Kai Wang, Han Li and Yazhong Ji
    Citation: European Journal of Medical Research 2024 29:4

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