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  1. Osteoporosis is characterized by deterioration of bone microarchitecture and reduced bone mass and can increase the risk of fracture. To reduce this risk, the aim of this study was to compare the combination e...

    Authors: Dalia M. Badary, Heba A. Galal, Mahmoud H. Abdelraheim, Mohamed I. Sedeek, Nesma M. Mohamed, Zakaria Y. Abd Elmageed and Magda M. Y. Farrag
    Citation: European Journal of Medical Research 2022 27:267
  2. Massage is widely used as a traditional technique during labor and delivery. The aim of this study was to evaluate the effect of Swedish massage with and without chamomile oil on delivery outcomes.

    Authors: Fatemeh Eskandari, Parvaneh Mousavi, Mahboubeh Valiani, Saeed Ghanbari and Mina Iravani
    Citation: European Journal of Medical Research 2022 27:266
  3. Helical TomoTherapy® is widely used for total body irradiation as a component of conditioning regimens before allogeneic bone-marrow transplantation. However, this technique limits the maximum length of a plannin...

    Authors: Mümtaz Köksal, Jonathan Baumert, Felix Schoroth, Thomas Müdder, Davide Scafa, David Koch, Christina Leitzen, Gustavo R. Sarria, Leonard C. Schmeel and Frank A. Giordano
    Citation: European Journal of Medical Research 2022 27:265
  4. Hepatic encephalopathy (HE) is a reversible syndrome of brain dysfunction caused by advanced liver disease. Weighted gene co-expression network analysis (WGCNA) could establish a robust co-expression network t...

    Authors: Chihao Zhang, Guqing Luo, Jiayun Lin, Zhifeng Zhao, Meng Luo and Hongjie Li
    Citation: European Journal of Medical Research 2022 27:264
  5. The poor prognosis of cervical spine surgery is mainly manifested as poor neurological recovery and the presence of new upper extremity dysfunction that promotes significant psychological and physiological bur...

    Authors: Peng Wang, Baoge Liu, Tianhua Rong and Bingxuan Wu
    Citation: European Journal of Medical Research 2022 27:263
  6. Soluble Klotho (S-Klotho) is an anti-aging protein mainly secreted by the kidneys. Hyperuricemia is prevalent among middle-aged and elderly individuals, which affects the development of various chronic disease...

    Authors: Haitao Xie, Ning Li, Guowei Zhou, Qian Liu, Haiyan Wang, Jie Han, Le Shen, Peng Yu, Jiandong Chen and Xiaohu Chen
    Citation: European Journal of Medical Research 2022 27:262
  7. At present, the relationship between serum homocysteine (Hcy), fibrinogen (FIB), lipoprotein-a (LPa), and PAD is uncertain, and there has been no meta-analysis to establish the dose–response relationship betwe...

    Authors: Hecheng Wang, Pengpeng Wu, Deying Jiang, Hao Zhang, Jian Zhang, Yu Zong and Yanshuo Han
    Citation: European Journal of Medical Research 2022 27:261
  8. Serum uric acid (SUA) acts as an antioxidant and abnormally low SUA may raise the risk of developing atherosclerotic disorders. There is a U-shaped association between SUA with cardiovascular diseases (CVDs) i...

    Authors: Yao-Wei Zou, Qian-Hua Li, Ying-Ying Zhu, Jie Pan, Jing-Wei Gao, Jian-Zi Lin, Tao Wu, Qian Zhang, Hu-Wei Zheng, Ying-Qian Mo, Jian-Da Ma and Lie Dai
    Citation: European Journal of Medical Research 2022 27:260
  9. Aberrant DNA methylation plays a crucial role in the progression of myeloid neoplasms. Previously, our literature reported that slit guidance ligand 2 (SLIT2) promoter methylation was associated with disease prog...

    Authors: De-long Wu, Yun Wang, Ting-juan Zhang, Ming-qiang Chu, Zi-jun Xu, Qian Yuan, Ji-chun Ma, Jiang Lin, Jun Qian and Jing-dong Zhou
    Citation: European Journal of Medical Research 2022 27:259
  10. Adequate sedation is essential for pediatric patients undergoing 3Tesla (T) magnetic resonance imaging (MRI). Using propofol alone is associated with patient arousing and adverse airway events. This study aime...

    Authors: Shang-xian Xu, Xi-sheng Shan, Jin-meng Gao, Hua-xian Liu, Wei-rong Chen, Shan-shan Gao, Fu-hai Ji, Ke Peng and Qian Wang
    Citation: European Journal of Medical Research 2022 27:258
  11. Hair graying, a prototypical sign of human aging, is a progressive loss of pigmentation from growing hair shafts caused by disease and as a side effect of medications. Cerebrolysin is a neuropeptide preparatio...

    Authors: Gustavo Villarreal-Reyna, Rodolfo Garza-Morales, Adolfo Soto-Domínguez, Lorena Montañez-Guerrero, Odila Saucedo-Cárdenas, Minerva Gómez-Flores, Jorge Alejandro Ocampo-Garza, José Juan Pérez-Trujillo and Roberto Montes-de-Oca-Luna
    Citation: European Journal of Medical Research 2022 27:257
  12. Despite the wide clinical application of checkpoint inhibitor immunotherapy in lung adenocarcinoma, its limited benefit to patients remains puzzling to researchers. One of the mechanisms of immunotherapy resis...

    Authors: Song Qiu, Ying Wang, Hui Rao, Qiuyang Que, Yanyang Wu, Rui Zhu, Xiaofei Feng, Jun Chi, Weiling Lai, Yihang Sun, Qi Xiao, Huaqiu Shi and Yi Xiang
    Citation: European Journal of Medical Research 2022 27:256
  13. The presentation of peptides and the subsequent immune response depend on the MHC characteristics and influence the specificity of the immune response. Several studies have found an association between HLA var...

    Authors: Johannes C. Fischer, Vera Balz, Danny Jazmati, Edwin Bölke, Noemi F. Freise, Verena Keitel, Torsten Feldt, Björn-Erik Ole Jensen, Johannes Bode, Tom Lüdde, Dieter Häussinger, Ortwin Adams, E. Marion Schneider, Jürgen Enczmann, Jutta M. Rox, Derik Hermsen…
    Citation: European Journal of Medical Research 2022 27:255
  14. Traumatic brain injury (TBI) causes mortality and long-term disability among young adults and imposes a notable cost on the healthcare system. In addition to the first physical hit, secondary injury, which is ...

    Authors: Nafiseh Gharizadeh, Morteza Ghojazadeh, Amirreza Naseri, Sanam Dolati, Faezeh Tarighat and Hassan Soleimanpour
    Citation: European Journal of Medical Research 2022 27:254
  15. Our goal was to examine the therapeutic effect of a self-designed digital six-axis external fixator technique for the correction of severe lower extremity deformities.

    Authors: Yufeng Lu, Jinfeng Li, Feng Qiao, Zhaochen Xu, Baogang Zhang, Bin Jia, Jinlong He, Liang Qi, Min Wang, Chen Fei and Xiaoming Cao
    Citation: European Journal of Medical Research 2022 27:252
  16. Patients with non-alcoholic fatty liver disease (NAFLD) may be more susceptible to coronavirus disease 2019 (COVID-19) and even more likely to suffer from severe COVID-19. Whether there is a common molecular p...

    Authors: Shi-Tao Jiang, Yao-Ge Liu, Lei Zhang, Xin-Ting Sang, Yi-Yao Xu and Xin Lu
    Citation: European Journal of Medical Research 2022 27:251
  17. Many women experience menstruation-related health issues during their child-bearing years. This study aimed to evaluate women’s tendency to seek Traditional Chinese Medicine (TCM) and/or Western Medicine (WM) ...

    Authors: Jong-Long Guo, Tzu-Chi Lee, Fen-He Lin, Hsiao-Pei Hsu and Chiu-Mieh Huang
    Citation: European Journal of Medical Research 2022 27:250
  18. We constructed a prognostic score (PS) model to predict the recurrence risk in patients previously diagnosed with laryngeal cancer (LC). Here the training dataset, consisting of 82 LC samples, was downloaded f...

    Authors: Yanan Liu, Zhiguang Gao, Cheng Peng and Xingli Jiang
    Citation: European Journal of Medical Research 2022 27:249
  19. Early prediction for short-term prognosis is essential for the management of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF). In this study, we aim to establish a noninvasive model for pr...

    Authors: Shuai Gao, Li-Yan Han, Yu-Chen Fan and Kai Wang
    Citation: European Journal of Medical Research 2022 27:248
  20. The diagnostic results of magnetic resonance imaging (MRI) are essential references for arthroscopy as an invasive procedure. A deviation between medical imaging diagnosis and arthroscopy results may cause irr...

    Authors: Yuan-Zhe Li, Yi Wang, Kai-Bin Fang, Hui-Zhong Zheng, Qing-Quan Lai, Yong-Fa Xia, Jia-Yang Chen and Zhang-sheng Dai
    Citation: European Journal of Medical Research 2022 27:247
  21. Leading cause of death in children under five, pediatric sepsis remains a significant global health threat. The 2020 Surviving Sepsis Campaign guidelines revised the management of septic shock and sepsis-assoc...

    Authors: Julian San Geroteo, Michaël Levy, Julien Gotchac, Olivier Brissaud and Stéphane Dauger
    Citation: European Journal of Medical Research 2022 27:246
  22. The present study aimed to observe the clinical efficacy of the external use of Qingluo San combined with diclofenac sodium double-release enteric capsules in the treatment of acute gouty arthritis (dampness–h...

    Authors: Chun Shu, Fang Yang, Fubing Zhu and Dongping Hua
    Citation: European Journal of Medical Research 2022 27:245
  23. COVID-19 is an infectious disease currently spreading worldwide. The COVID-19 virus requires angiotensin-converting enzyme 2, an enzyme that plays a vital role in regulating the apelinergic system for entry in...

    Authors: Farzaneh Rostamzadeh, Hamid Najafipour, Rostam Yazdani, Samira Nakhaei and Ahmad Alinaghi Langari
    Citation: European Journal of Medical Research 2022 27:243
  24. Emerging studies indicated that circular RNA hsa_circ_ 0023404 and its target miR-217/MARK1 axis play a critical role in cancer progression such as non-small cell lung cancer and cervical cancer. However, the ...

    Authors: Zhuoying Chen, Meixiu Huang, Jiaying You, Yanhua Lin, Qiaoyun Huang and Caiping He
    Citation: European Journal of Medical Research 2022 27:242
  25. Sex differences exist in the structure and function of human heart. The patterns of ventricular repolarization in normal electrocardiograms (ECG) differ in men and women: men ECG pattern displays higher T-wave...

    Authors: Chandra Prajapati, Jussi Koivumäki, Mari Pekkanen-Mattila and Katriina Aalto-Setälä
    Citation: European Journal of Medical Research 2022 27:241
  26. Cardiovascular disease (CVD) represents the leading cause of death worldwide. The identification of individuals at increased risk of CVD is essential to reduce its morbidity and mortality globally. Based on ex...

    Authors: Sarah Krieg, Karel Kostev, Mark Luedde, Andreas Krieg, Tom Luedde, Christoph Roderburg and Sven H. Loosen
    Citation: European Journal of Medical Research 2022 27:240
  27. Neoadjuvant chemotherapy (NAC) for locally advanced gastric and gastroesophageal junction adenocarcinoma (LAGC) has been recommended in several guidelines. However, there is no global consensus about the optim...

    Authors: Tongya Wang, Changyang Li, Xiang Li, Jing Zhai, Shoulin Wang and Lizong Shen
    Citation: European Journal of Medical Research 2022 27:239
  28. To observe the effect and mechanism of alpha-adrenergic receptor inhibitor phentolamine (PTL) in a rabbit model of acute pulmonary embolism (APE) combined with shock.

    Authors: Yuting Wang, Li Qiu, Delong Yu, Yijun Yu, Liqun Hu and Ye Gu
    Citation: European Journal of Medical Research 2022 27:238
  29. Liver injury (LI) has been frequently observed in patients with dilated cardiomyopathy (DCM), whereas its prognostic value remains blurry. We attempted to appraise the prognostic effect of LI in patients with ...

    Authors: Hai-Yan Wang, Yuan Huang, Xiao-Zhen Chen, Zi-Lan Zhang and Chun Gui
    Citation: European Journal of Medical Research 2022 27:237
  30. Viruses that emerge pose challenges for treatment options as their uniqueness would not know completely. Hence, many viruses are causing high morbidity and mortality for a long time. Despite large diversity, v...

    Authors: Lekha Gandhi, Deepti Maisnam, Deepika Rathore, Preeti Chauhan, Anvesh Bonagiri and Musturi Venkataramana
    Citation: European Journal of Medical Research 2022 27:236
  31. The current study investigated whether the changes in patient care in times of the COVID-19 pandemic, especially the reduction of in-person visits, would result in a deterioration of the arrhythmic and clinica...

    Authors: Christian Hauck, Andreas Schober, Alexander Schober, Sabine Fredersdorf, Ute Hubauer, Lars Maier, Andreas Keyser, Moritz Huttelmaier, Thomas Fischer, Carsten Jungbauer and Ekrem Ücer
    Citation: European Journal of Medical Research 2022 27:234
  32. Coronary microvascular dysfunction (CMD) is a leading cause of ischemic heart disease. Over the past few decades, considerable progress has been made with respect to research on CMD. The present study summariz...

    Authors: Jing Gao, Tiantian Meng, Min Li, Ruolin Du, Jingyi Ding, Anqi Li, Shanshan Yu, Yixiang Li and Qingyong He
    Citation: European Journal of Medical Research 2022 27:233
  33. Angiogenesis is a vital biological process involving blood vessels forming from pre-existing vascular systems. This process contributes to various physiological activities, including embryonic development, hai...

    Authors: Ahmad Hoseinzadeh, Hamed Ghoddusi Johari, Mohammad Hossein Anbardar, Lobat Tayebi, Ehsan Vafa, Milad Abbasi, Ahmad Vaez, Ali Golchin, Ali Mohammad Amani and Ali Jangjou
    Citation: European Journal of Medical Research 2022 27:232
  34. Acute lung injury (ALI), a prevalent complication of severe acute pancreatitis (SAP), is also a leading contributor to respiratory failure and even death of SAP patients. Here, we intended to investigate the f...

    Authors: Lei Wang, Na Yuan, Yuanli Li, Qinqin Ma, Ying Zhou, Zhifei Qiao, Shutie Li, Chunyan Liu, Liqian Zhang, Meng Yuan and Jianjing Sun
    Citation: European Journal of Medical Research 2022 27:231
  35. Surgery is one of the most important treatments for bladder cancer, including local tumor excision and radical cystectomy. At present, studies on the causes of death for contemporary survivors, especially wome...

    Authors: Qian Lyu, Yu Nie, Jiazheng Yuan and Dong Wang
    Citation: European Journal of Medical Research 2022 27:230
  36. The use of empirical anti-infective medication calls for the identification of common pathogens and accurate infectious biomarkers. However, clinical pharmacists’ anti-infective experience in the field of obst...

    Authors: Jing Jin, Xiucong Fan, Xiaohui Dong, Xiaobo Zhai, Yabin Ma and Jing Tang
    Citation: European Journal of Medical Research 2022 27:229
  37. The purpose of this study was to observe the morphologic characteristics of patent foramen ovale (PFO) by transesophageal echocardiography (TEE), and to analyze its correlation with right-to-left shunt (RLS) o...

    Authors: Jiali Tian and Xiaobo Chen
    Citation: European Journal of Medical Research 2022 27:228
  38. Septic shock is associated with increased mortality. Predicting mortality, including early prediction for septic shock patients in intensive care units (ICUs), remains an important challenge.

    Authors: Tie-Ning Zhang, Peng-Hui Hao, Shan-Yan Gao, Chun-Feng Liu and Ni Yang
    Citation: European Journal of Medical Research 2022 27:227
  39. Evidence regarding the timing of the application of mechanical ventilation among patients with severe coronavirus disease (COVID-19) is insufficient. This systematic review and meta-analysis aimed to evaluate ...

    Authors: Hyeon-Jeong Lee, Joohae Kim, Miyoung Choi, Won-Il Choi, Joonsung Joh, Jungeun Park and Junghyun Kim
    Citation: European Journal of Medical Research 2022 27:226
  40. Immune checkpoint inhibitors (ICIs) therapy elicits admirable anti-tumor responses across many types of cancer. Growing evidence point to a link to Mediator complex subunit 12 (MED12) and DNA damage repair (DD...

    Authors: Yong Zhou, Yuan Tan, Qin Zhang, Qianqian Duan and Jun Chen
    Citation: European Journal of Medical Research 2022 27:225
  41. Bile pigments, such as bilirubin and biliverdin, are end products of the heme degradation pathway in mammals and are widely known for their cytotoxic effects. However, recent studies have revealed that they ex...

    Authors: Mizuki Seya, Toshiyuki Aokage, Tsuyoshi Nojima, Atsunori Nakao and Hiromichi Naito
    Citation: European Journal of Medical Research 2022 27:224
  42. Gamma knife radiosurgery (GK) is a commonly used approach for the treatment of intracranial lesions. Its radiation response is typically not immediate, but delayed. In this study, we analyzed cases from a pros...

    Authors: Chiung-Chyi Shen, Rong-San Jiang, Men-Yin Yang, Weir-Chiang You, Ming-Hsi Sun, Meei-Ling Sheu, Liang-Yi Pan, Jason Sheehan and Hung-Chuan Pan
    Citation: European Journal of Medical Research 2022 27:223
  43. To compare the clinical efficacy of lumbar endoscopic Delta large channel and microscopic tubular Quadrant channel unilateral laminotomy with bilateral decompression in the treatment of elderly patients with l...

    Authors: Jianing Zhang, Dingjie Liang, Mengmeng Xu, Kun Yan, Dapeng Zhang and Weiqing Qian
    Citation: European Journal of Medical Research 2022 27:222
  44. Here we report the evaluation of the frequency of subjective and objective otolaryngologic findings and therapeutic results in 32 patients with mitochondrial encephalomyopathy (MEM) from September 2001 to June...

    Authors: Haishan Long, Cheng Wen, Juan Zhao, Jiawei Wang, Yang Li, Xinxing Fu and Lihui Huang
    Citation: European Journal of Medical Research 2022 27:221
  45. In previous studies, haemorrhage occurred only with large infarct sizes, and studies found a moderate correlation between the extent of necrosis and haemorrhage, but the extent of infarction size in these stud...

    Authors: Rui Xia, Tong Zhu, Yu Zhang, Bo He, Yushu Chen, Lei Wang, Yang Zhou, Jichun Liao, Jie Zheng, Yongmei Li, Fajin Lv and Fabao Gao
    Citation: European Journal of Medical Research 2022 27:220
  46. To explore how to measure LAPEq accurately and quantitatively, that is, the left atrial pressure (LAP) measured and calculated by equation method using mitral regurgitation spectrum.

    Authors: Yan Jin, Chao-yang Wen, Fengjie Yue, Huishan Wang, Liancheng Yin, Yang Zhao, Keming Mao and Fangran Xin
    Citation: European Journal of Medical Research 2022 27:217

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