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  1. The purpose of the present study was to analyze the relationship between the levels of air pollutants and respiratory function/physical efficiency of pre-adolescent children living in the Upper Silesian Indust...

    Authors: A. Zebrowska and R. Mankowski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):224

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  2. Several reports indicate that lungs are the extralymphatic site most commonly affected in patients with Hodgkin lymphoma; however, the data in children are rather limited. This retrospective study aimed to ass...

    Authors: T. Urasinski, E. Kamienska, A. Gawlikowska-Sroka, T. Ociepa, E. Maloney, K. Chosia and A. Walecka

    Citation: European Journal of Medical Research 2010 15(Suppl 2):206

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  3. Nasal septum deformation (NSD) may cause breathing dysfunction. The reason for a septal deviation is the developmental anomaly in growth of the elastic septum or its skeleton. Such a type of deviation is calle...

    Authors: I. Teul, G. Slawinski, J. Lewandowski, E. Dzieciolowska-Baran, A. Gawlikowska-Sroka and F. Czerwinski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):202

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  4. Type 1 diabetes is a metabolic disease characterized by an autoimmune, T-cell dependent destruction of insulin producing pancreatic beta cells. T regulatory cells (Tregs) are critical regulators of immune tole...

    Authors: A. Szypowska, A. Stelmaszczyk-Emmel, U. Demkow and W. Luczynski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):198

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  5. Codeine represents a commonly used drug to suppress cough. Central antitussive effect of codeine has been confirmed in a number of animal studies. However, available data related to antitussive activity of cod...

    Authors: M. Simera, I. Poliacek and J. Jakus

    Citation: European Journal of Medical Research 2010 15(Suppl 2):184

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  6. Alpha-1-proteinase inhibitor (α1-PI) is the most relevant protease inhibitor in the lung. Patients with hereditary deficiency of α1-PI suffer from an impaired hepatic synthesis of α1-PI in the liver and in conseq...

    Authors: R. Siekmeier

    Citation: European Journal of Medical Research 2010 15(Suppl 2):164

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  7. To characterize the ventilatory responses to resistive loading or unloading, we studied the effects of breathing 79% helium-21% oxygen (He-O2), 79% argon-21% oxygen (Ar-O2) and 79% SF6-21% oxygen (SF6-O2) on the ...

    Authors: M. O. Segizbaeva

    Citation: European Journal of Medical Research 2010 15(Suppl 2):157

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  8. The prevalence of obesity in children and adolescents has been increasing worldwide. As in adults, childhood obesity is closely related to hypertension, dyslipidemia, type 2 diabetes, and insulin resistance (I...

    Authors: B. Pyrzak, M. Ruminska, K. Popko and U. Demkow

    Citation: European Journal of Medical Research 2010 15(Suppl 2):147

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  9. TNF-α is one of the most important factors in the development and course of inflammation. It is suggested that polymorphism located in the 5'regulatory region of the TNF-α gene at position 308 (guanine [G]→ ad...

    Authors: B. Pyrzak, A. Wisniewska, K. Popko, U. Demkow and A. M. Kucharska

    Citation: European Journal of Medical Research 2010 15(Suppl 2):141

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  10. The vagus nerve plays a special role in the control of respiratory system activity which represents the parasympathetic part of the autonomic nervous system. A small bronchial innervation by the sympathetic sy...

    Authors: I. Poziomkowska-Gesicka, E. Dzieciolowska-Baran, A. Gawlikowska-Sroka, D. Slowik-Zylka and T. Sroczynski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):135

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  11. Serotonin (5-HT) and its receptors are present in central, the brain stem, and peripheral, the carotid body, tissues controlling the ventilatory responses to hypoxia. The exact action of serotonin and its natu...

    Authors: M. Pozdzik, D. Zajac, I. Zasada, Z. Czarnocki, Z. Matysiak, A. Mazzatenta and M. Pokorski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):128

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  12. Oxygen transport is optimized at the cellular level, since oxygen serves as the terminal electron acceptor in mitochondrial oxidative phosphorylation and several enzymatic processes require molecular oxygen as...

    Authors: G. Petruccelli, V. Verratti, J. Antosiewicz, A. Cataldi, A. Mazzatenta and C. Di Giulio

    Citation: European Journal of Medical Research 2010 15(Suppl 2):108

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  13. Peripheral chemoreceptors residing predominantly in the carotid body monitor changes in arterial blood oxygen and are mechanistically linked to the cardiorespiratory control by the autonomic nervous system. En...

    Authors: T. Rassaf, R. Westenfeld, J. Balzer, T. Lauer, M. Merx, J. Floege, S. Steiner, C. Heiss, M. Kelm and C. Meyer

    Citation: European Journal of Medical Research 2010 15(Suppl 2):83

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  14. Chemosensory neurons respond to stimulation induced by gasses, volatile and non-volatile compounds. Neuronal excitation mediated via second messengers involves typically: cGMP, cAMP, or IP3. Transduction pathways...

    Authors: A. Mazzatenta, C. Di Giulio and M. Pokorski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):79

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  15. Osteoporosis may significantly impair the final result of lung transplantation. The purpose of study is to determine the prevalence of osteoporosis with the regard to risk factors for osteoporosis in patients ...

    Authors: D. Jastrzebski, W. Lutogniewska, M. Ochman, A. Margas, K. Kowalski, J. Wyrwol, B. Ksiazek, J. Wojarski, S. Zeglen, D. Ziora and J. Kozielski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):68

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  16. Chronic obstructive pulmonary disease (COPD) is characterized by irreversible progressive airflow limitation related to tobacco smoking. This limitation is caused by chronic inflammation of the airways and lun...

    Authors: A. Holownia, R. M. Mroz, T. Skopinski, A. Kielek, A. Kolodziejczyk, E. Chyczewska and J. J. Braszko

    Citation: European Journal of Medical Research 2010 15(Suppl 2):64

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  17. Fas/APO-1 (CD95) and Fas Ligand (FasL) is a major mediator system that activates programmed cell death (apoptosis) and is most important for pulmonary cellular homeostasis. Another form of Fas, circulating sol...

    Authors: F. Hoffmeyer, J. Henry, G. Borowitzki, R. Merget, J. Bünger, T. Brüning and M. Raulf-Heimsoth

    Citation: European Journal of Medical Research 2010 15(Suppl 2):60

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  18. Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the product of alternative RNA splicing of db gene. According to its structural difference...

    Authors: E. Gorska, K. Popko, A. Stelmaszczyk-Emmel, O. Ciepiela, A. Kucharska and M. Wasik

    Citation: European Journal of Medical Research 2010 15(Suppl 2):50

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  19. Menopause is a health and social problem that affects a large number of women. Inadequate quantity of steroid hormones also impacts quality of the mucous membrane of the oral cavity. During menopausal age, man...

    Authors: M. Golecka-Bakowska, E. Mierzwinska-Nastalska and M. Bychawska

    Citation: European Journal of Medical Research 2010 15(Suppl 2):46

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  20. Breathing-related sleep disorders cover several conditions (isolated snoring, UARS - upper airway resistance syndrome, obstructive sleep apnea, hypopnea, obesity hypoventilation syndrome) characterized by a va...

    Authors: E. Dzieciolowska-Baran, A. Gawlikowska-Sroka, I. Poziomkowska-Gesicka, I. Teul-Swiniarska and T. Sroczynski

    Citation: European Journal of Medical Research 2010 15(Suppl 2):36

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  21. Neutrophil elastase, metalloproteinases, and their inhibitors play an important role in the development of chronic obstructive pulmonary disease (COPD), resulting in extensive tissue damage and malfunctioning ...

    Authors: U. Demkow and F. J. van Overveld

    Citation: European Journal of Medical Research 2010 15(Suppl 2):27

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  22. Detection of allergen-induced basophil activation by flow cytometry has been shown to be a useful tool for allergy diagnosis.

    Authors: O. Ciepiela, J. Zwiazek, A. Zawadzka-Krajewska, I. Kotula, M. Kulus and U. Demkow

    Citation: European Journal of Medical Research 2010 15(Suppl 2):21

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  23. The resistance of T lymphocytes to Fas-mediated apoptosis is an important feature of atopic asthma. The only effective causative treatment of atopic diseases is immunotherapy. Clinical efficacy of sublingual i...

    Authors: O. Ciepiela, A. Zawadzka-Krajewska, I. Kotula, M. Wasik and U. Demkow

    Citation: European Journal of Medical Research 2010 15(Suppl 2):17

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 15 Supplement 2

  24. Notch receptors are critical determinants of cell fate in a variety of organisms. Notch signaling is involved in the chondrogenic specification of neural crest cells. Aberrant Notch activity has been implicate...

    Authors: CH Siar, KO Ha, LO Aung, K Nakano, H Tsujigiwa, H Nagatsuka, KH Ng and T Kawakami

    Citation: European Journal of Medical Research 2010 15:456

    Content type: Research

    Published on:

  25. Measuring arterial stiffness using pulse wave velocity (PWV) has become an important tool to assess vascular function and cardiovascular mortality. For subject with hypertension, end-stage renal disease and di...

    Authors: A Mitchell, A Opazo Saez, M Kos, O Witzke, A Kribben and J Nürnberger

    Citation: European Journal of Medical Research 2010 15:452

    Content type: Research

    Published on:

  26. Resistance to cisplatin in the course of chemotherapy contributes to the poor prognosis of small cell lung cancer (SCLC). B cell lymphoma-2 is the founding member of a large family of proteins that either prom...

    Authors: J Biagosch, RM Huber and A Bergner

    Citation: European Journal of Medical Research 2010 15:448

    Content type: Research

    Published on:

  27. The selective degradation of many proteins in eukaryotic cells is carried out by the ubiquitin system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserv...

    Authors: SU Sixt, HP Jennissen, M Winterhalter and M Laub

    Citation: European Journal of Medical Research 2010 15:428

    Content type: Research

    Published on:

    The Retraction Note to this article has been published in European Journal of Medical Research 2011 16:II

  28. Once metastasized, despite a variety of therapeutic options, the prognosis of patients with malignant melanoma (MM) is still poor. Therefore, the search for reliable markers to identify patients with high risk...

    Authors: UH Frey, A Fritz, S Rotterdam, KW Schmid, A Potthoff, P Altmeyer, W Siffert and NH Brockmeyer

    Citation: European Journal of Medical Research 2010 15:422

    Content type: Research

    Published on:

  29. Replication of HIV-1 after cell entry is essentially dependent on the reverse transcriptase (RT). Antiretroviral drugs impairing the function of the RT currently aim at the polymerase subunit. One reason for f...

    Authors: I Michels, S Staszewski, L Gürtler, G Nisius, A Müller, L Locher, H-W Doerr and M Stürmer

    Citation: European Journal of Medical Research 2010 15:415

    Content type: Research

    Published on:

  30. The deadly threat of systemic infections with coagulase negative Staphylococcus lugdunensis despite an appropriate antibiotic therapy has only recently been recognized. The predominant infectious focus observed s...

    Authors: M Woznowski, I Quack, E Bölke, M Peiper, C Matuschek, SG Gatermann, LC Rump and G Schieren

    Citation: European Journal of Medical Research 2010 15:410

    Content type: Case report

    Published on:

  31. Given sparse research on the issue, this study sought to shed light upon the interactions of alexithymia, emotion processing, and social anxiety in adults with attention-deficit hyperactivity disorder (ADHD).

    Authors: M-A Edel, A Rudel, C Hubert, D Scheele, M Brüne, G Juckel and H-J Assion

    Citation: European Journal of Medical Research 2010 15:403

    Content type: Review

    Published on:

  32. We found that locations of arginine-specific gingipain (RGP) in the cellular fractions in the crude extract, envelope, vesicles, and culture supernatants were 48%, 16%, 17%, and 31%, respectively, and the corr...

    Authors: S Oishi, M Miyashita, A Kiso, Y Kikuchi, O Ueda, K Hirai, Y Shibata and S Fujimura

    Citation: European Journal of Medical Research 2010 15:397

    Content type: Research

    Published on:

  33. Diverticula of the esophagus represent a rare pathological entity. Distinct classifications of the disease imply different surgical concepts. Surgery should be reserved for symptomatic patients only. Minimally...

    Authors: T Laubert, P Hildebrand, UJ Roblick, M Kraus, H Esnaashari, P Wellhöner and HP Bruch

    Citation: European Journal of Medical Research 2010 15:390

    Content type: Research

    Published on:

  34. The constantly growing amount of different kinds of colloid fluids necessitates comparative investigations with regards to the safety and effectivity in clinical use of these preparations. Hence we compared th...

    Authors: M Winterhalter, P Malinski, O Danzeisen, S Sixt, E Monaca, T Jüttner, M Peiper, P Kienbaum, A Koester and N Rahe-Meyer

    Citation: European Journal of Medical Research 2010 15:383

    Content type: Research

    Published on:

  35. Dendritic cells (DC) are the initiators and modulators of the immune responses. Some species of pathogenic microorganisms have developed immune evasion strategies by controlling antigen presentation function o...

    Authors: G Changyong, M Sun, H Li, N Brockmeyer and N Wu

    Citation: European Journal of Medical Research 2010 15:377

    Content type: Research

    Published on:

  36. The RAINBOW survey is a multinational observational study assessing the tolerability and efficacy of ritonavir-boosted saquinavir (SQV/r), using the 500 mg film-coated SQV formulation, in routine clinical prac...

    Authors: C Stephan, H Jaeger, A Carganico, G Knecht, T Lutz, C Mayr, FA Mosthaf, S Koeppe, M Mueller, E Wolf, A Tappe, E Wellmann and H Knechten

    Citation: European Journal of Medical Research 2010 15:369

    Content type: Research

    Published on:

  37. Diffuse large B-cell lymphoma usually starts as a rapidly growing mass in an internal lymph node and can grow in other areas such as the bone or intestines. About 1/3 of these lymphomas are confined to one par...

    Authors: E Bölke, M Peiper, C Matuschek, G Schieren, R Glombick, C Förster, W Budach and K Orth

    Citation: European Journal of Medical Research 2010 15:367

    Content type: Case report

    Published on:

  38. To compare the pelvic floor function of primiparous women to women after a second delivery regarding symptoms of urinary and anal incontinence, anal sphincter ruptures and bladder-neck mobility.

    Authors: K Jundt, I Scheer, V von Bodungen, F Krumbachner, K Friese and UM Peschers

    Citation: European Journal of Medical Research 2010 15:362

    Content type: Research

    Published on:

  39. Hilar cholangiocarcinoma is the fourth most common gastrointestinal malignancy. CA19-9 and CEA are helpful devices in the management of gastrointestinal malignancies and belong to clinical routine in surgical ...

    Authors: B Juntermanns, S Radunz, M Heuer, S Hertel, H Reis, JP Neuhaus, S Vernadakis, T Trarbach, A Paul and GM Kaiser

    Citation: European Journal of Medical Research 2010 15:357

    Content type: Research

    Published on:

  40. In general, chronic pancreatitis (CP) primarily requires conservative treatment. The chronic pain syndrome and complications make patients seek surgical advice, frequently after years of progression. In the pa...

    Authors: P Hildebrand, S Dudertadt, R Czymek, FG Bader, UJ Roblick, H-P Bruch and T Jungbluth

    Citation: European Journal of Medical Research 2010 15:351

    Content type: Research

    Published on:

  41. Volumetric assessment of the liver regularly yields discrepant results between pre- and intraoperatively determined volumes. Nevertheless, the main factor responsible for this discrepancy remains still unclear...

    Authors: SM Niehues, JK Unger, M Malinowski, J Neymeyer, B Hamm and M Stockmann

    Citation: European Journal of Medical Research 2010 15:345

    Content type: Research

    Published on:

  42. Systemic treatment of head and neck squamous cell carcinoma (HNSCC) includes a variety of antineoplastic drugs. However, drug-resistance interferes with the effectiveness of chemotherapy. Preclinical testing m...

    Authors: PJ Schuler, S Trellakis, J Greve, M Bas, C Bergmann, E Bölke, G Lehnerdt, S Mattheis, AE Albers, S Brandau, S Lang, TL Whiteside, H Bier and TK Hoffmann

    Citation: European Journal of Medical Research 2010 15:337

    Content type: Research

    Published on:

  43. Streptococcus intermedius - a member of the Streptococcus anginosus group - is part of the normal microbial flora of the oral cavity. Despite being regarded as a harmless apathogenic commensal, Streptococcus int...

    Authors: A Neumayr, R Kubitz, JG Bode, P Bilk and D Häussinger

    Citation: European Journal of Medical Research 2010 15:319

    Content type: Case report

    Published on:

  44. Prevotella nigrescens, lacking siderophores was found to bind to the hemoproteins. The binding was observed also in the envelope which was prepared by sonication of the cell. The binding occurred in the pH-depen...

    Authors: M Miyashita, S Oishi, A Kiso, Y Kikuchi, O Ueda, K Hirai, Y Shibata and S Fujimura

    Citation: European Journal of Medical Research 2010 15:314

    Content type: Research

    Published on:

  45. The patch test (PT) with its modification - the strip patch test (SPT) - is the standard in vivo procedure to diagnose an allergic contact dermatitis (ACD). To date, none of the in vitro tests for the diagnosi...

    Authors: H Dickel, O Kuss, J Kamphowe, P Altmeyer and S Höxtermann

    Citation: European Journal of Medical Research 2010 15:303

    Content type: Research

    Published on:

  46. The concept of total mesorectal excision has revolutionised rectal cancer surgery. TME reduces the rate of local recurrence and tumour associated mortality. However, in clinical trials only 50% of the removed ...

    Authors: T Herzog, O Belyaev, AM Chromik, D Weyhe, CA Mueller, J Munding, A Tannapfel, W Uhl and MH Seelig

    Citation: European Journal of Medical Research 2010 15:292

    Content type: Research

    Published on:

  47. Sarcomatoid renal cell cancer (RCC) is a distinct histological variant of RCC that is associated with rapid progression and a poor prognosis. The optimal treatment for patients with sarcomatoid RCC remains to ...

    Authors: M Staehler, N Haseke, A Roosen, T Stadler, M Bader, M Siebels, A Karl and CG Stief

    Citation: European Journal of Medical Research 2010 15:287

    Content type: Research

    Published on:

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