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  1. The purpose of the present study was to analyze the relationship between the levels of air pollutants and respiratory function/physical efficiency of pre-adolescent children living in the Upper Silesian Indust...

    Authors: A. Zebrowska and R. Mankowski
    Citation: European Journal of Medical Research 2010 15(Suppl 2):224

    This article is part of a Supplement: Volume 15 Supplement 2

  2. Type 1 diabetes is a metabolic disease characterized by an autoimmune, T-cell dependent destruction of insulin producing pancreatic beta cells. T regulatory cells (Tregs) are critical regulators of immune tole...

    Authors: A. Szypowska, A. Stelmaszczyk-Emmel, U. Demkow and W. Luczynski
    Citation: European Journal of Medical Research 2010 15(Suppl 2):198

    This article is part of a Supplement: Volume 15 Supplement 2

  3. Alpha-1-proteinase inhibitor (α1-PI) is the most relevant protease inhibitor in the lung. Patients with hereditary deficiency of α1-PI suffer from an impaired hepatic synthesis of α1-PI in the liver and in conseq...

    Authors: R. Siekmeier
    Citation: European Journal of Medical Research 2010 15(Suppl 2):164

    This article is part of a Supplement: Volume 15 Supplement 2

  4. To characterize the ventilatory responses to resistive loading or unloading, we studied the effects of breathing 79% helium-21% oxygen (He-O2), 79% argon-21% oxygen (Ar-O2) and 79% SF6-21% oxygen (SF6-O2) on the ...

    Authors: M. O. Segizbaeva
    Citation: European Journal of Medical Research 2010 15(Suppl 2):157

    This article is part of a Supplement: Volume 15 Supplement 2

  5. The prevalence of obesity in children and adolescents has been increasing worldwide. As in adults, childhood obesity is closely related to hypertension, dyslipidemia, type 2 diabetes, and insulin resistance (I...

    Authors: B. Pyrzak, M. Ruminska, K. Popko and U. Demkow
    Citation: European Journal of Medical Research 2010 15(Suppl 2):147

    This article is part of a Supplement: Volume 15 Supplement 2

  6. Serotonin (5-HT) and its receptors are present in central, the brain stem, and peripheral, the carotid body, tissues controlling the ventilatory responses to hypoxia. The exact action of serotonin and its natu...

    Authors: M. Pozdzik, D. Zajac, I. Zasada, Z. Czarnocki, Z. Matysiak, A. Mazzatenta and M. Pokorski
    Citation: European Journal of Medical Research 2010 15(Suppl 2):128

    This article is part of a Supplement: Volume 15 Supplement 2

  7. Osteoporosis may significantly impair the final result of lung transplantation. The purpose of study is to determine the prevalence of osteoporosis with the regard to risk factors for osteoporosis in patients ...

    Authors: D. Jastrzebski, W. Lutogniewska, M. Ochman, A. Margas, K. Kowalski, J. Wyrwol, B. Ksiazek, J. Wojarski, S. Zeglen, D. Ziora and J. Kozielski
    Citation: European Journal of Medical Research 2010 15(Suppl 2):68

    This article is part of a Supplement: Volume 15 Supplement 2

  8. Chronic obstructive pulmonary disease (COPD) is characterized by irreversible progressive airflow limitation related to tobacco smoking. This limitation is caused by chronic inflammation of the airways and lun...

    Authors: A. Holownia, R. M. Mroz, T. Skopinski, A. Kielek, A. Kolodziejczyk, E. Chyczewska and J. J. Braszko
    Citation: European Journal of Medical Research 2010 15(Suppl 2):64

    This article is part of a Supplement: Volume 15 Supplement 2

  9. Fas/APO-1 (CD95) and Fas Ligand (FasL) is a major mediator system that activates programmed cell death (apoptosis) and is most important for pulmonary cellular homeostasis. Another form of Fas, circulating sol...

    Authors: F. Hoffmeyer, J. Henry, G. Borowitzki, R. Merget, J. Bünger, T. Brüning and M. Raulf-Heimsoth
    Citation: European Journal of Medical Research 2010 15(Suppl 2):60

    This article is part of a Supplement: Volume 15 Supplement 2

  10. Neutrophil elastase, metalloproteinases, and their inhibitors play an important role in the development of chronic obstructive pulmonary disease (COPD), resulting in extensive tissue damage and malfunctioning ...

    Authors: U. Demkow and F. J. van Overveld
    Citation: European Journal of Medical Research 2010 15(Suppl 2):27

    This article is part of a Supplement: Volume 15 Supplement 2

  11. Detection of allergen-induced basophil activation by flow cytometry has been shown to be a useful tool for allergy diagnosis.

    Authors: O. Ciepiela, J. Zwiazek, A. Zawadzka-Krajewska, I. Kotula, M. Kulus and U. Demkow
    Citation: European Journal of Medical Research 2010 15(Suppl 2):21

    This article is part of a Supplement: Volume 15 Supplement 2

  12. The resistance of T lymphocytes to Fas-mediated apoptosis is an important feature of atopic asthma. The only effective causative treatment of atopic diseases is immunotherapy. Clinical efficacy of sublingual i...

    Authors: O. Ciepiela, A. Zawadzka-Krajewska, I. Kotula, M. Wasik and U. Demkow
    Citation: European Journal of Medical Research 2010 15(Suppl 2):17

    This article is part of a Supplement: Volume 15 Supplement 2

  13. Notch receptors are critical determinants of cell fate in a variety of organisms. Notch signaling is involved in the chondrogenic specification of neural crest cells. Aberrant Notch activity has been implicate...

    Authors: CH Siar, KO Ha, LO Aung, K Nakano, H Tsujigiwa, H Nagatsuka, KH Ng and T Kawakami
    Citation: European Journal of Medical Research 2010 15:456
  14. Measuring arterial stiffness using pulse wave velocity (PWV) has become an important tool to assess vascular function and cardiovascular mortality. For subject with hypertension, end-stage renal disease and di...

    Authors: A Mitchell, A Opazo Saez, M Kos, O Witzke, A Kribben and J Nürnberger
    Citation: European Journal of Medical Research 2010 15:452
  15. Resistance to cisplatin in the course of chemotherapy contributes to the poor prognosis of small cell lung cancer (SCLC). B cell lymphoma-2 is the founding member of a large family of proteins that either prom...

    Authors: J Biagosch, RM Huber and A Bergner
    Citation: European Journal of Medical Research 2010 15:448
  16. The selective degradation of many proteins in eukaryotic cells is carried out by the ubiquitin system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserv...

    Authors: SU Sixt, HP Jennissen, M Winterhalter and M Laub
    Citation: European Journal of Medical Research 2010 15:428

    The Retraction Note to this article has been published in European Journal of Medical Research 2011 16:II

  17. Once metastasized, despite a variety of therapeutic options, the prognosis of patients with malignant melanoma (MM) is still poor. Therefore, the search for reliable markers to identify patients with high risk...

    Authors: UH Frey, A Fritz, S Rotterdam, KW Schmid, A Potthoff, P Altmeyer, W Siffert and NH Brockmeyer
    Citation: European Journal of Medical Research 2010 15:422
  18. Replication of HIV-1 after cell entry is essentially dependent on the reverse transcriptase (RT). Antiretroviral drugs impairing the function of the RT currently aim at the polymerase subunit. One reason for f...

    Authors: I Michels, S Staszewski, L Gürtler, G Nisius, A Müller, L Locher, H-W Doerr and M Stürmer
    Citation: European Journal of Medical Research 2010 15:415
  19. The deadly threat of systemic infections with coagulase negative Staphylococcus lugdunensis despite an appropriate antibiotic therapy has only recently been recognized. The predominant infectious focus observed s...

    Authors: M Woznowski, I Quack, E Bölke, M Peiper, C Matuschek, SG Gatermann, LC Rump and G Schieren
    Citation: European Journal of Medical Research 2010 15:410
  20. Given sparse research on the issue, this study sought to shed light upon the interactions of alexithymia, emotion processing, and social anxiety in adults with attention-deficit hyperactivity disorder (ADHD).

    Authors: M-A Edel, A Rudel, C Hubert, D Scheele, M Brüne, G Juckel and H-J Assion
    Citation: European Journal of Medical Research 2010 15:403
  21. We found that locations of arginine-specific gingipain (RGP) in the cellular fractions in the crude extract, envelope, vesicles, and culture supernatants were 48%, 16%, 17%, and 31%, respectively, and the corr...

    Authors: S Oishi, M Miyashita, A Kiso, Y Kikuchi, O Ueda, K Hirai, Y Shibata and S Fujimura
    Citation: European Journal of Medical Research 2010 15:397
  22. Diverticula of the esophagus represent a rare pathological entity. Distinct classifications of the disease imply different surgical concepts. Surgery should be reserved for symptomatic patients only. Minimally...

    Authors: T Laubert, P Hildebrand, UJ Roblick, M Kraus, H Esnaashari, P Wellhöner and HP Bruch
    Citation: European Journal of Medical Research 2010 15:390
  23. The constantly growing amount of different kinds of colloid fluids necessitates comparative investigations with regards to the safety and effectivity in clinical use of these preparations. Hence we compared th...

    Authors: M Winterhalter, P Malinski, O Danzeisen, S Sixt, E Monaca, T Jüttner, M Peiper, P Kienbaum, A Koester and N Rahe-Meyer
    Citation: European Journal of Medical Research 2010 15:383
  24. Dendritic cells (DC) are the initiators and modulators of the immune responses. Some species of pathogenic microorganisms have developed immune evasion strategies by controlling antigen presentation function o...

    Authors: G Changyong, M Sun, H Li, N Brockmeyer and N Wu
    Citation: European Journal of Medical Research 2010 15:377
  25. The RAINBOW survey is a multinational observational study assessing the tolerability and efficacy of ritonavir-boosted saquinavir (SQV/r), using the 500 mg film-coated SQV formulation, in routine clinical prac...

    Authors: C Stephan, H Jaeger, A Carganico, G Knecht, T Lutz, C Mayr, FA Mosthaf, S Koeppe, M Mueller, E Wolf, A Tappe, E Wellmann and H Knechten
    Citation: European Journal of Medical Research 2010 15:369
  26. Diffuse large B-cell lymphoma usually starts as a rapidly growing mass in an internal lymph node and can grow in other areas such as the bone or intestines. About 1/3 of these lymphomas are confined to one par...

    Authors: E Bölke, M Peiper, C Matuschek, G Schieren, R Glombick, C Förster, W Budach and K Orth
    Citation: European Journal of Medical Research 2010 15:367
  27. To compare the pelvic floor function of primiparous women to women after a second delivery regarding symptoms of urinary and anal incontinence, anal sphincter ruptures and bladder-neck mobility.

    Authors: K Jundt, I Scheer, V von Bodungen, F Krumbachner, K Friese and UM Peschers
    Citation: European Journal of Medical Research 2010 15:362
  28. Hilar cholangiocarcinoma is the fourth most common gastrointestinal malignancy. CA19-9 and CEA are helpful devices in the management of gastrointestinal malignancies and belong to clinical routine in surgical ...

    Authors: B Juntermanns, S Radunz, M Heuer, S Hertel, H Reis, JP Neuhaus, S Vernadakis, T Trarbach, A Paul and GM Kaiser
    Citation: European Journal of Medical Research 2010 15:357
  29. In general, chronic pancreatitis (CP) primarily requires conservative treatment. The chronic pain syndrome and complications make patients seek surgical advice, frequently after years of progression. In the pa...

    Authors: P Hildebrand, S Dudertadt, R Czymek, FG Bader, UJ Roblick, H-P Bruch and T Jungbluth
    Citation: European Journal of Medical Research 2010 15:351
  30. Volumetric assessment of the liver regularly yields discrepant results between pre- and intraoperatively determined volumes. Nevertheless, the main factor responsible for this discrepancy remains still unclear...

    Authors: SM Niehues, JK Unger, M Malinowski, J Neymeyer, B Hamm and M Stockmann
    Citation: European Journal of Medical Research 2010 15:345
  31. Systemic treatment of head and neck squamous cell carcinoma (HNSCC) includes a variety of antineoplastic drugs. However, drug-resistance interferes with the effectiveness of chemotherapy. Preclinical testing m...

    Authors: PJ Schuler, S Trellakis, J Greve, M Bas, C Bergmann, E Bölke, G Lehnerdt, S Mattheis, AE Albers, S Brandau, S Lang, TL Whiteside, H Bier and TK Hoffmann
    Citation: European Journal of Medical Research 2010 15:337
  32. Streptococcus intermedius - a member of the Streptococcus anginosus group - is part of the normal microbial flora of the oral cavity. Despite being regarded as a harmless apathogenic commensal, Streptococcus int...

    Authors: A Neumayr, R Kubitz, JG Bode, P Bilk and D Häussinger
    Citation: European Journal of Medical Research 2010 15:319
  33. Prevotella nigrescens, lacking siderophores was found to bind to the hemoproteins. The binding was observed also in the envelope which was prepared by sonication of the cell. The binding occurred in the pH-depen...

    Authors: M Miyashita, S Oishi, A Kiso, Y Kikuchi, O Ueda, K Hirai, Y Shibata and S Fujimura
    Citation: European Journal of Medical Research 2010 15:314
  34. The patch test (PT) with its modification - the strip patch test (SPT) - is the standard in vivo procedure to diagnose an allergic contact dermatitis (ACD). To date, none of the in vitro tests for the diagnosi...

    Authors: H Dickel, O Kuss, J Kamphowe, P Altmeyer and S Höxtermann
    Citation: European Journal of Medical Research 2010 15:303
  35. The concept of total mesorectal excision has revolutionised rectal cancer surgery. TME reduces the rate of local recurrence and tumour associated mortality. However, in clinical trials only 50% of the removed ...

    Authors: T Herzog, O Belyaev, AM Chromik, D Weyhe, CA Mueller, J Munding, A Tannapfel, W Uhl and MH Seelig
    Citation: European Journal of Medical Research 2010 15:292
  36. Sarcomatoid renal cell cancer (RCC) is a distinct histological variant of RCC that is associated with rapid progression and a poor prognosis. The optimal treatment for patients with sarcomatoid RCC remains to ...

    Authors: M Staehler, N Haseke, A Roosen, T Stadler, M Bader, M Siebels, A Karl and CG Stief
    Citation: European Journal of Medical Research 2010 15:287
  37. Tumor-related methylated DNA and circulating tumor cells (CTC) in the peripheral blood might be of prognostic importance in breast cancer. Thus, the aim of our study was to examine free methylated DNA and CTC ...

    Authors: C Matuschek, E Bölke, G Lammering, PA Gerber, M Peiper, W Budach, H Taskin, HB Prisack, G Schieren, K Orth and H Bojar
    Citation: European Journal of Medical Research 2010 15:277
  38. Merkel cell carcinoma (MCC) is a relatively rare, polyomavirus associated, primary neuroendocrine carcinoma of the skin which is usually arising from dermal skin layers. However, the origin of MCC in the subcu...

    Authors: T Gambichler, S Kobus, A Kreuter, U Wieland and M Stücker
    Citation: European Journal of Medical Research 2010 15:274
  39. For many patients confronted with chronic diseases, spirituality/religiosity is a relevant resource to cope. While most studies on patients' spiritual needs refer to the care of patients at the end of life, ou...

    Authors: A Büssing, HJ Balzat and P Heusser
    Citation: European Journal of Medical Research 2010 15:266
  40. Non-operative management of blunt splenic injury in adults has been applied increasingly at the end of the last century. Therefore, the lifelong risk of overwhelming post-splenectomy infection has been the maj...

    Authors: M Heuer, G Taeger, GM Kaiser, D Nast-Kolb, CA Kühne, S Ruchholtz, R Lefering, A Paul and S Lendemans
    Citation: European Journal of Medical Research 2010 15:258
  41. To compare the function of the pelvic floor in primiparae before and during pregnancy with the status post partum concerning symptoms of incontinence, sphincter ruptures, bladder-neck mobility and the influenc...

    Authors: K Jundt, I Scheer, B Schiessl, K Karl, K Friese and UM Peschers
    Citation: European Journal of Medical Research 2010 15:246
  42. Few data are available about the efficacy of maraviroc (MVC) during routine use. We characterized indications for MVC use and the efficacy of MVC in clinical practice.

    Authors: S Reuter, P Braken, B Jensen, S Sierra-Aragon, M Oette, M Balduin, R Kaiser and D Häussinger
    Citation: European Journal of Medical Research 2010 15:231
  43. Use of potent antiplatelet drugs requires evaluation of platelet function. While platelet function in elective cases is usually assessed in a central laboratory environment, there is also an urgent need for ra...

    Authors: A. A. Hanke, K. Roberg, E. Monaca, T. Sellmann, C. F. Weber, N. Rahe-Meyer and K. Görlinger
    Citation: European Journal of Medical Research 2010 15:214
  44. Renal impairment is a common complication of multiple myeloma occuring in up to 50% of patients at some stage in their disease. Due to occurrence of cast nephropathies we hypothesized circulatory dysregulation...

    Authors: U. Schiemann, H. C. Kaiser, M. Götzberger, R. Schmidmaier, F. Bantle and C. Straka
    Citation: European Journal of Medical Research 2010 15:210
  45. Antiseptics are frequently used for the prophylaxis and treatment of local infections of chronic wounds. Whereas local antiseptics in general have a positive effect on wound healing an uncritical use may impai...

    Authors: C. Marquardt, C. Matuschek, E. Bölke, P. A. Gerber, M. Peiper, J. v. Seydlitz-Kurzbach, B. A. Buhren, M. van Griensven, W. Budach, M. Hassan, G. Kukova, R. Mota, D. Höfer, K. Orth and W. Fleischmann
    Citation: European Journal of Medical Research 2010 15:204

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