Detection of promoter hypermethylation of the CpG island of E-cadherin in gastric cardiac adenocarcinoma

Table 2 E-cadherin methylation and immunohistochemical staining characteristics of GCA patients

Group	methylation status		P	Immunohistochemical staining		P
	M	U		-	+
TNM stage
I	4	4		2	6
II	18	14		13	9
III	29	9		26	12
IV	12	2	0.015^a	10	4	0.002^a
Pathological differentiation of tumor
moderate	22	20		20	2
poor-moderate	25	9		18	16
poor	16	0	0.003^b	13	3	0.022^b

^a P value of stage III and IV patients against stage I and II patients, ^b P value of poor differentiation group against moderate and poor-moderate groups

ISSN: 2047-783X