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  1. Trauma accounts for a third of the deaths in Western countries, exceeded only by cardiovascular disease and cancer. The high risk of massive bleeding, which depends not only on the type of fractures, but also ...

    Authors: Matteo Renzulli, Anna Maria Ierardi, Nicolò Brandi, Sofia Battisti, Emanuela Giampalma, Giovanni Marasco, Daniele Spinelli, Tiziana Principi, Fausto Catena, Mansoor Khan, Salomone Di Saverio, Giampaolo Carrafiello and Rita Golfieri

    Citation: European Journal of Medical Research 2021 26:123

    Content type: Review

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  2. High-flow nasal cannula (HFNC) and noninvasive ventilation (NIV) have been used for the treatment of COPD and respiratory failure in clinical settings. We aimed to evaluate the efficacy and safety of HFNC ther...

    Authors: Zhiping Xu, Lingxia Zhu, Jingye Zhan and Lijun Liu

    Citation: European Journal of Medical Research 2021 26:122

    Content type: Research

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  3. Percutaneous coronary interventions (PCI) of bifurcation stenoses are both complex and challenging. Stenting strategies share that the stents’ side cells must be carefully explored and appropriately prepared u...

    Authors: Alper Öner, Paula Rosam, Finja Borowski, Niels Grabow, Stefan Siewert, Wolfram Schmidt, Klaus-Peter Schmitz and Michael Stiehm

    Citation: European Journal of Medical Research 2021 26:121

    Content type: Research

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  4. Cases of acute sphenoid sinusitis complicated by septic cavernous sinus (CS) thrombosis and internal carotid artery (ICA) stenosis are rarely reported. Different causative pathogens have been reported for this...

    Authors: Bo-An Chen, Zhuo-Hao Liu, Chi-Cheng Chuang and Cheng-Chi Lee

    Citation: European Journal of Medical Research 2021 26:120

    Content type: Review

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  5. For a patient presenting with fever, multiple lymphadenopathy and splenomegaly, pathogen infection should be preferentially considered, followed by lymphoid malignancies. When traditional laboratory and pathol...

    Authors: Xiao Cui, Yongfeng Wu, Lin Jia, Jing Chang, Chuanyun Li, Caiping Guo, Tong Zhang, Yingmin Ma and Yulin Zhang

    Citation: European Journal of Medical Research 2021 26:119

    Content type: Case report

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  6. Large bone defects resulting from musculoskeletal tumours, infections, or trauma are often unable to heal spontaneously. The challenge for surgeons is to avoid amputation, and provide the best functional outco...

    Authors: Filippo Migliorini, Gerardo La Padula, Ernesto Torsiello, Filippo Spiezia, Francesco Oliva and Nicola Maffulli

    Citation: European Journal of Medical Research 2021 26:118

    Content type: Review

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  7. Interleukin-6 receptor antagonists (IL-6RAs) and steroids are emerging immunomodulatory therapies for severe and critical coronavirus disease (COVID-19). In this preliminary report, we aim to describe the epid...

    Authors: Marwa Amer, Ahmed M. Kamel, Mohammed Bawazeer, Khalid Maghrabi, Abid Butt, Talal Dahhan, Eiad Kseibi, Syed Moazzum Khurshid, Mohammed Abujazar, Razan Alghunaim, Muath Rabee, Maal Abualkhair, Ali Al-Janoubi, Abeer Turki AlFirm, Ognjen Gajic, Allan J. Walkey…

    Citation: European Journal of Medical Research 2021 26:117

    Content type: Research

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  8. Pregnant women are at high risk for severe influenza. However, maternal influenza vaccination uptake in most World Health Organization (WHO) European Region countries remains low, despite the presence of wides...

    Authors: Gbadebo Collins Adeyanju, Elena Engel, Laura Koch, Tabea Ranzinger, Imtiaz Bin Mohammed Shahid, Micheal G. Head, Sarah Eitze and Cornelia Betsch

    Citation: European Journal of Medical Research 2021 26:116

    Content type: Review

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  9. Fatty liver is one of the most common pre-existing illnesses; it can cause liver injury, leading to further complications in coronavirus disease 2019 patients. Our goal is to determine if pre-existing fatty li...

    Authors: Arash Ziaee, Ghodsiyeh Azarkar and Masood Ziaee

    Citation: European Journal of Medical Research 2021 26:115

    Content type: Research

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  10. Pneumomediastinum is a rare complication of COVID-19 pneumonia, which may or may not be associated with invasive ventilatory support. Therefore, the report and findings associated with its evolution can be of ...

    Authors: Sérgio Henrique Bastos Damous, Jones Pessoa dos Santos Junior, Álvaro Vicente Alvarez Pezzano, Mohamad Abdul Majid Chams, Nathaly Haritov, Ricardo Waksman, Helber Vidal Gadelha Lima, Jocielle dos Santos Miranda, Roberto Rasslan and Edivaldo Massazo Utiyama

    Citation: European Journal of Medical Research 2021 26:114

    Content type: Case report

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  11. CD146 is a tight junction-associated molecule involved in maintaining endothelial barrier, and balancing immune–inflammation response, in cardiovascular disease. Notably, peripheral CD146+ cells significantly ups...

    Authors: Yan-hui Wang, Chen-xin Li, Jessica M. Stephenson, Sean P. Marrelli, Yan-ming Kou, Da-zhi Meng and Ting Wu

    Citation: European Journal of Medical Research 2021 26:113

    Content type: Research

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  12. Patients with coronavirus disease 2019 (COVID-19) who undergo surgery have impaired postoperative outcomes and increased mortality. Consequently, elective and semi-urgent operations on the increasing number of...

    Authors: Sven Flemming, Mohammed K. Hankir, Simon Kusan, Manuel Krone, Friedrich Anger, Christoph-Thomas Germer and Armin Wiegering

    Citation: European Journal of Medical Research 2021 26:112

    Content type: Research

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  13. Eggerthella lenta is a normal human microflora that is anaerobic, non-sporulating, and Gram positive. However, an increasing number of studies have shown that it could also be an important pathogen for humans, ev...

    Authors: Shuming Jiang, Jianfei E, Dengchao Wang, Yanjiao Zou, Xiao Liu, Hualiang Xiao, Yuan Wen and Zongyao Chen

    Citation: European Journal of Medical Research 2021 26:111

    Content type: Review

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  14. Adult-onset Still’s disease (AOSD) should be considered in the differential diagnosis of patients with endocarditis, with or without a cardiac decompensation.

    Authors: Larissa Valor-Méndez, Bernhard Manger, Alexander Cavallaro, Stephan Achenbach, Georg Schett and Jürgen Rech

    Citation: European Journal of Medical Research 2021 26:110

    Content type: Case report

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  15. Mycobacterium abscessus subspecies massiliense is a non-tuberculous mycobacteriosis and was subdivided from Mycobacterium abscessus in 2006. This article is the first report on nasopharyngitis caused by Mycobacte...

    Authors: Yamato Oki, Hiromitsu Hatakeyama, Masanori Komatsu, Yasuhiro Isono, Hidetaka Ikemiyagi, Jun Tsukiji, Ryoko Higa and Nobuhiko Oridate

    Citation: European Journal of Medical Research 2021 26:109

    Content type: Case report

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  16. COVID-19, the pandemic disease caused by infection with SARS-CoV-2, may take highly variable clinical courses, ranging from symptom-free and pauci-symptomatic to fatal disease. The goal of the current study wa...

    Authors: Johannes C. Fischer, Albrecht G. Schmidt, Edwin Bölke, Markus Uhrberg, Verena Keitel, Torsten Feldt, Björn Jensen, Dieter Häussinger, Ortwin Adams, E. Marion Schneider, Vera Balz, Jürgen Enczmann, Jutta Rox, Derik Hermsen, Karin Schulze-Bosse, Detlef Kindgen-Milles…

    Citation: European Journal of Medical Research 2021 26:107

    Content type: Research

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  17. Combined spinal epidural anesthesia (CSEA) is commonly performed in cesarean deliveries. However, it is difficult to perform in obese parturients because of positioning challenges. The aim of this study was to...

    Authors: Yilu Zhou, Wei Chen, Shuangqiong Zhou, Yiyi Tao, Zhendong Xu and Zhiqiang Liu

    Citation: European Journal of Medical Research 2021 26:106

    Content type: Research

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  18. Platelet-rich plasma (PRP) has the potential to be used for bone regeneration. However, its effect on osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) and its effect on cell autoph...

    Authors: Yunhe Xu, Xiaoning Wang, Wenshu Liu and Weiwei Lu

    Citation: European Journal of Medical Research 2021 26:105

    Content type: Research

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  19. Authors: Johannes C. Fischer, Albrecht G. Schmidt, Edwin Bölke, Verena Keitel, Torsten Feldt, Björn Jensen, Noemi F. Freise, Dieter Häussinger, E. Marion Schneider, Derik Hermsen, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Jan Haussmann, Balint Tamaskovics, Christian Plettenberg, Kathrin Scheckenbach…

    Citation: European Journal of Medical Research 2021 26:104

    Content type: Correction

    Published on:

    The original article was published in European Journal of Medical Research 2021 26:87

  20. This study aimed to appraise the efficacy of a 577-nm high-power optically pumped semiconductor laser (HOPSL) for the treatment of inflammatory acne.

    Authors: E. M. Mohamed, K. M. Tawfik, I. B. Elsayed, E. Bölke and P. A. Gerber

    Citation: European Journal of Medical Research 2021 26:103

    Content type: Research

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  21. This study aimed to present the case of a boy with acute distress syndrome (ARDS) treated with low-dose umbilical cord blood (UCB) therapy and explore the underlying possible mechanism.

    Authors: Shuang Liu, Huili Shen, Siyuan Huang, Rong Liu and Dong Qu

    Citation: European Journal of Medical Research 2021 26:100

    Content type: Case report

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  22. The coronavirus disease 2019 (COVID‐19) is associated with a wide clinical spectrum of skin manifestations, including urticarial, vesicular, vasculitic and chilblain‐like lesions. Recently, delayed skin reacti...

    Authors: Norman-Philipp Hoff, Noemi F. Freise, Albrecht G. Schmidt, Parnian Firouzi-Memarpuri, Julia Reifenberger, Tom Luedde, Edwin Bölke, Stephan Meller, Bernhard Homey, Torsten Feldt, Björn Erik Ole Jensen, Verena Keitel, Livia Schmidt, Kitti Maas, Jan Haussmann, Balint Tamaskovics…

    Citation: European Journal of Medical Research 2021 26:98

    Content type: Research

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  23. Interventricular septal hematoma is an extremely rare complication following congenital heart surgery. During cardiac surgery, interventricular septal hematomas can be detected only by intraoperative transesop...

    Authors: Young-Eun Jang, Jin-Tae Kim and Ji-Hyun Lee

    Citation: European Journal of Medical Research 2021 26:97

    Content type: Case report

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  24. Oxygenation serves as a cornerstone in the treatment of COVID-19, and several methods have been extensively studied so far. Herein, we aimed to systematically review the studies discussing hyperbaric oxygen th...

    Authors: Shahram Oliaei, SeyedAhmad SeyedAlinaghi, Mohammad Mehrtak, Amirali Karimi, Tayebeh Noori, Pegah Mirzapour, Alireza Shojaei, Mehrzad MohsseniPour, Seyed Peyman Mirghaderi, Sanam Alilou, Parnian Shobeiri, Hadiseh Azadi Cheshmekabodi, Esmaeil Mehraeen and Omid Dadras

    Citation: European Journal of Medical Research 2021 26:96

    Content type: Review

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  25. The purpose of present study was to explore the mechanism of nuclear factor-kappa B (NF-κB), phosphatidylinositol 3-kinase (PI3K)/protein kinase B(PKB/Akt) and mitogen-activated protein kinase (MAPK) signaling...

    Authors: Zheng Li, Xiao Wang, Tian-pei Hong, Hao-jie Wang, Zhan-yi Gao and Meng Wan

    Citation: European Journal of Medical Research 2021 26:94

    Content type: Research

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  26. To investigate the value of Dickkopf-related protein 3 (DKK3) on aerobic glycolysis in pancreatic cancer cells, where DKK3-overexpression is used to determine its effects on CD4+ T cells.

    Authors: Qingqu Guo, Yiming Chu, Hongbo Li, Dike Shi, Lele Lin, Weifeng Lan and Dan Wu

    Citation: European Journal of Medical Research 2021 26:93

    Content type: Research

    Published on:

  27. Herpes zoster (HZ), or shingles, is a clinical syndrome resulting from the reactivation of latent varicella zoster virus (VZV) within the sensory ganglia. We evaluated the safety and tolerability of ES16001 (e...

    Authors: Jeon Hwang-Bo, Byungwook Kim, Dae Won Park, Yeong-Geun Lee, Jeong Eun Kwon, Jae-Yong Chung and Se Chan Kang

    Citation: European Journal of Medical Research 2021 26:92

    Content type: Research

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  28. We present a case of bacterial endocarditis with both methicillin-sensitive and methicillin-resistant Staphylococcus aureus, which based on typing, originated from two distinct clones. Such a case may be misinter...

    Authors: Yotam Kolben, Yuval Ishay, Henny Azmanov, Assaf Rokney, Moti Baum, Sharon Amit and Ran Nir-Paz

    Citation: European Journal of Medical Research 2021 26:91

    Content type: Case report

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  29. Pulmonary artery intimal sarcoma (PAS) is a very rare disease, its prevalence is about 0.001–0.003%. PAS is often misdiagnosed as acute or chronic pulmonary thromboembolism due to its clinical presentation and...

    Authors: Xiaofang Bai and Litao Ruan

    Citation: European Journal of Medical Research 2021 26:89

    Content type: Case report

    Published on:

  30. Epilepsy is one of the most common chronic neurological diseases. Despite the great variety and prevalence of antiepileptic drug treatments, one-third of epilepsies remain drug resistant. The frontal lobe is e...

    Authors: Jia Zhang, Heng Zhang, Yang Li, Meng Yuan, Jinxiu Zhang, Huan Luo, Zeshan Yao and Jing Gan

    Citation: European Journal of Medical Research 2021 26:88

    Content type: Case report

    Published on:

  31. COVID-19 infection is a major threat to patients and health care providers around the world. One solution is the vaccination against SARS-CoV-2.

    Authors: Johannes C. Fischer, Albrecht G. Schmidt, Edwin Bölke, Verena Keitel, Torsten Feldt, Björn Jensen, Noemi F. Freise, Dieter Häussinger, E. Marion Schneider, Derik Hermsen, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Jan Haussmann, Balint Tamaskovics, Christian Plettenberg, Kathrin Scheckenbach…

    Citation: European Journal of Medical Research 2021 26:87

    Content type: Letter to the Editor

    Published on:

    The Correction to this article has been published in European Journal of Medical Research 2021 26:104

  32. As one of the leading causes of elderly patients’ hospitalisation, proximal femur fractures (PFFs) will present an increasing socioeconomic problem in the near future. This is a result of the demographic chang...

    Authors: H. Fischer, T. Maleitzke, C. Eder, S. Ahmad, U. Stöckle and K. F. Braun

    Citation: European Journal of Medical Research 2021 26:86

    Content type: Review

    Published on:

  33. Streptococcus suis (Ss) is a Gram-positive and anaerobic zoonotic pathogen that is susceptible to all populations and can cause meningitis, septicemia, endocarditis and arthritis in humans.

    Authors: Eryi Zhao, Daimei Wang, Na Li, Shixiong Huang, Zhongyan Zhao, Shijun Hu, Xiangying He and Guoqiang Wen

    Citation: European Journal of Medical Research 2021 26:85

    Content type: Research

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  34. The COVID-19 pandemic has markedly impacted on cultural, political, and economic structures all over the world. Several aspects of its pathogenesis and related clinical consequences have not yet been elucidate...

    Authors: Filippo Migliorini, Ernesto Torsiello, Filippo Spiezia, Francesco Oliva, Markus Tingart and Nicola Maffulli

    Citation: European Journal of Medical Research 2021 26:84

    Content type: Review

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  35. Brain abscess due to the Nocardia genus is rarely reported and it is usually found in immunocompromised patients. Treatment of Nocardia brain abscess is troublesome and requires consideration of the severity of t...

    Authors: Jiangqin Song, Lian Dong, Yan Ding and Junyang Zhou

    Citation: European Journal of Medical Research 2021 26:83

    Content type: Case report

    Published on:

  36. Previous studies have shown the association between Campylobacter species infection and that environmental factors, poor oral hygiene in particular, are linked to an increased risk of esophageal cancer (EC). Howe...

    Authors: Arisara Poosari, Thitima Nutravong, Prakasit Sa-ngiamwibool, Wises Namwat, Supaporn Chatrchaiwiwatana and Piti Ungareewittaya

    Citation: European Journal of Medical Research 2021 26:82

    Content type: Research

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  37. Nucleus pulposus cells’ (NPCs’) degeneration is mainly responsible for the intervertebral disc degeneration (IDD), which is closely related to inflammatory response. Among the major proinflammatory factors tha...

    Authors: Cenhao Wu, Jun Ge, Ming Yang, Qi Yan, Yingjie Wang, Hao Yu, Huilin Yang and Jun Zou

    Citation: European Journal of Medical Research 2021 26:81

    Content type: Research

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  38. It is necessary to analyze the characteristics and risk factors of catheter-related bloodstream infection (CRBSI) in newborns with peripherally inserted central catheter (PICC).

    Authors: Yan Hu, Yun Ling, Yingying Ye, Lu Zhang, Xiaojing Xia, Qianwen Jiang and Fang Sun

    Citation: European Journal of Medical Research 2021 26:80

    Content type: Research

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  39. The coronavirus disease 2019(COVID-19) has affected mortality worldwide. The Cox proportional hazard (CPH) model is becoming more popular in time-to-event data analysis. This study aimed to evaluate the clinic...

    Authors: Ghodsiyeh Azarkar and Freshteh Osmani

    Citation: European Journal of Medical Research 2021 26:79

    Content type: Research

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  40. Patients with maxillofacial deformities require orthognathic surgeries to correct occlusion. The surgical procedure may lead to massive bleeding, which is associated with haematoma, respiratory obstruction, an...

    Authors: Chenyu Jin, Xiang Lv, Yu Sun and Hong Jiang

    Citation: European Journal of Medical Research 2021 26:78

    Content type: Research

    Published on:

  41. Among the several complications associated with anterior cervical discectomy and fusion (ACDF), airway compromise is considered one of the serious life-threatening conditions and usually requires emergent trea...

    Authors: Dong-Gune Chang, Jong-Beom Park, Hong Jin Kim and Soo-Bin Park

    Citation: European Journal of Medical Research 2021 26:77

    Content type: Case report

    Published on:

  42. The aim of this study was to evaluate the expression of four up/down-regulated inflammatory miRNAs and their mRNA targets in the serum samples of COVID-19 patients with different grades. Also, we investigated ...

    Authors: Reza Keikha, Seyed Mohammad Hashemi-Shahri and Ali Jebali

    Citation: European Journal of Medical Research 2021 26:75

    Content type: Research

    Published on:

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