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  1. Content type: Research

    This study focuses on the identification of conserved genes involved in myocardial infarction (MI), and then analyzed the differentially expressed genes (DEGs) between the incident and recurrent events to iden...

    Authors: Linlin Qiu and Xueqing Liu

    Citation: European Journal of Medical Research 2019 24:22

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  2. Content type: Research

    Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a crucial mediator in response to inflammation. Myricetin protects cardiomyocytes against inflammatory injury. However, it’s still unexplored ...

    Authors: Jinliang Sun, Jianhui Sun and Xuezhong Zhou

    Citation: European Journal of Medical Research 2019 24:20

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  3. Content type: Research

    Skin biopsies are often used in daily practice for the diagnosis of acute (aGvHD) or chronic graft versus host disease (cGvHD). With the latest understanding in pathogenesis and new National Institute of Healt...

    Authors: M. C. H. Hogenes, L. C. J. te Boome, D. C. van der Valk, M. R. van Dijk, R. A. de Weger, J. Kuball and P. J. van Diest

    Citation: European Journal of Medical Research 2019 24:19

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  4. Content type: Review

    Injuries to the acromioclavicular (AC) joint are one of the most common among sporting injuries of the upper extremity. Several studies investigated different treatment options comparing surgical and non-surgi...

    Authors: F. Allemann, S. Halvachizadeh, M. Waldburger, F. Schaefer, C. Pothmann, H. C. Pape and T. Rauer

    Citation: European Journal of Medical Research 2019 24:18

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  5. Content type: Research

    Visceral artery aneurysms (VAA) are rare vascular lesions. Clinically silent VAA are increasingly detected by cross-sectional imaging but some lesions are at risk for rupture with severe bleeding. The aim of t...

    Authors: Vittorio Branchi, Carsten Meyer, Frauke Verrel, Alexander Kania, Edwin Bölke, Alexander Semaan, Arne Koscielny, Jörg C. Kalff and Hanno Matthaei

    Citation: European Journal of Medical Research 2019 24:17

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  6. Content type: Research

    Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular neoplasm with increasing incidence. However, its clinical characteristics remain unclear due to its low incidence. This study aimed to invest...

    Authors: Xin Wu, Binglu Li, Chaoji Zheng, Tao Hong and Xiaodong He

    Citation: European Journal of Medical Research 2019 24:16

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  7. Content type: Research

    Only few studies have investigated the effect of topical application of tranexamic acid (TXA) on “minimally” invasive joint surgical procedures in which articular cartilage is preserved; for this reason, actua...

    Authors: Remo Goderecci, Ilaria Giusti, Stefano Necozione, Benedetta Cinque, Sandra D’Ascenzo, Vincenza Dolo and Vittorio Calvisi

    Citation: European Journal of Medical Research 2019 24:15

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  8. Content type: Research

    Cognitive impairment and reduced quality of life is a common condition in patients with heart failure (HF). Percutaneous mitral valve repair using (PMVR) MitraClip (MC) has emerged as a promising interventiona...

    Authors: Valentin Terhoeven, Christoph Nikendei, Anna Cranz, Matthias Weisbrod, Nicolas Geis, Philip W. Raake, Hugo A. Katus, Wolfgang Herzog, Hans-Christoph Friederich, Jobst-Hendrik Schultz and Sven T. Pleger

    Citation: European Journal of Medical Research 2019 24:14

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  9. Content type: Research

    Some studies have suggested that blood glucose fluctuation and C-peptide level were considered as predictive factors for carotid artery intima–media thickness (CIMT). However, the relationships of these variab...

    Authors: Min Liu, Li Ao, Xinyu Hu, Jianning Ma, Kena Bao, Ye Gu, Jing Zhao and Weiping Huang

    Citation: European Journal of Medical Research 2019 24:13

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  10. Content type: Research

    The aim of the present work was to assess systemic hemodynamic changes using PiCCo monitoring in a porcine model of E. coli-induced fulminant sepsis.

    Authors: Mariann Berhés, Norbert Németh, Katalin Pető, Ádám Deák, Endre Hajdú, Ábel Molnár, Péter Árkosy, Judit Szabó and Béla Fülesdi

    Citation: European Journal of Medical Research 2019 24:11

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  11. Content type: Research

    Difficulty in wound healing is one common complication of diabetes mellitus. The study explored whether the therapeutic effect of human umbilical cord mesenchymal stem cells (hUCMSCs) on diabetic ulcer wound w...

    Authors: Yanfu Han, Tianjun Sun, Yanqing Han, Lingling Lin, Chang Liu, Jing Liu, Guangzhi Yan and Ran Tao

    Citation: European Journal of Medical Research 2019 24:10

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  12. Content type: Research

    In pursuit of improvement in cardiopulmonary resuscitation (CPR), new technologies for the measurement and assessment of CPR quality are implemented. In our study, we assessed the kinematics of the rescuer dur...

    Authors: Bogusław Bucki, Dariusz Waniczek, Robert Michnik, Jacek Karpe, Andrzej Bieniek, Arkadiusz Niczyporuk, Joanna Makarska, Tomasz Stepien, Dariusz Myrcik and Hanna Misiołek

    Citation: European Journal of Medical Research 2019 24:9

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  13. Content type: Research

    Early diagnosis of congenital syphilis (CS) is difficult. This study aimed to determine the serological response discipline of syphilis passive antibody (SPA) in infants born to mothers with syphilis and provi...

    Authors: Hong-Mei Wang, Yu-Ye Li, Li-Ping He, Ying-Kui Cao, Tian-Xiang Dong and Yi-Qun Kuang

    Citation: European Journal of Medical Research 2019 24:7

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  14. Content type: Research

    Alternative techniques for nasal dorsum augmentation are of paramount importance in reconstructive and plastic surgery. In contrast to autologous cartilage grafts, tissue-engineered grafts can be created de no...

    Authors: Paul S. Wiggenhauser, Elizabeth R. Balmayor, Nicole Rotter and Jan T. Schantz

    Citation: European Journal of Medical Research 2019 24:6

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  15. Content type: Research

    Cancer, one of the leading causes of death worldwide, develops when the normal balance between mitosis and apoptosis is disrupted. The subsequently increased proliferation rate or decreased apoptosis rate of c...

    Authors: Manuela Malsy, Diane Bitzinger, Bernhard Graf and Anika Bundscherer

    Citation: European Journal of Medical Research 2019 24:5

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  16. Content type: Research

    Multimorbidity and polypharmacy are common challenges in the treatment of older trauma patients. Therefore, various integrated care models were developed over the last few years, merging the expertise of geria...

    Authors: Johannes Gleich, Daniel Pfeufer, Christian Zeckey, Wolfgang Böcker, Markus Gosch, Christian Kammerlander and Carl Neuerburg

    Citation: European Journal of Medical Research 2019 24:4

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  17. Content type: Research

    OO (osteoid osteoma) is a common, osteoblastic, benign bone tumor but rarely seen in the hand region. There is still some debate about the diagnosis and treatment of hand OOs. In the present study, we aimed to...

    Authors: Ozgur Erdogan and Volkan Gurkan

    Citation: European Journal of Medical Research 2019 24:3

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  18. Content type: Case Report

    Multi-drug-resistant bacteria (e.g. Carbapenem-resistant Acinetobacter baumannii, extended-spectrum betalactamase or carbapenemase-producing enterobacteriaceae) are emerging in early-onset infections. So far, the...

    Authors: G. Siebenbürger, B. Grabein, T. Schenck, C. Kammerlander, W. Böcker and C. Zeckey

    Citation: European Journal of Medical Research 2019 24:2

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  19. Content type: Editorial

    Cancer and cardiovascular diseases are the main causes for morbidity and mortality in modern society. In the United States of America (USA), over 1.7 million new cancer cases will presumably be observed in 201...

    Authors: Lars Michel and Tienush Rassaf

    Citation: European Journal of Medical Research 2019 24:1

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  20. Content type: Research

    Recent studies have reported that endocrine-disrupting compound (EDC) exposure is related to food sensitization. Bisphenol A diglycidyl ether (BADGE) is one of the most widespread EDCs and its biological effec...

    Authors: Mayumi Tsuji, Chihaya Koriyama, Yasuhiro Ishihara, Christoph F. A. Vogel and Toshihiro Kawamoto

    Citation: European Journal of Medical Research 2018 23:61

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  21. Content type: Research

    Fingertip injuries treated with occlusive dressings (ODs) lead to nearly scar-free, functionally, and aesthetically pleasing results. We hypothesized that paracrine factors in the wound fluid (secretome) may i...

    Authors: Michael K. Cerny, Ursula Hopfner, Manuela Kirsch, Elisabeth-Maria Haas, Fan Wu, Riccardo Giunta, Hans-Guenther Machens, Dominik Duscher, Holger Erne and Arndt F. Schilling

    Citation: European Journal of Medical Research 2018 23:60

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  22. Content type: Research

    To evaluate the detection rate and image quality in CT-body-packer-screening at different radiation-dose levels and to determine a dose threshold that enables a reliable detection of incorporated body packs an...

    Authors: Joel Aissa, Edwin Bölke, Lino M. Sawicki, Elisabeth Appel, Christoph Thomas, Philipp Heusch, Martin Sedlmair, Karl Krzymyk, Patric Kröpil, Gerald Antoch and Johannes Boos

    Citation: European Journal of Medical Research 2018 23:59

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  23. Content type: Research

    External dacryocystorhinostomy (DCR) is considered as the gold standard in the treatment of acquired nasolacrimal duct obstruction. However, many advances have been made towards the development of modern minim...

    Authors: Joel M. Mor, Mario Matthaei, Holger Schrumpf, Konrad R. Koch, Edwin Bölke and Ludwig M. Heindl

    Citation: European Journal of Medical Research 2018 23:58

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  24. Content type: Review

    The effect of statin treatment on circulating coenzyme Q10 (CoQ10) has been studied in numerous randomized controlled trails (RCTs). However, whether statin treatment decreases circulating CoQ10 is still contr...

    Authors: Hua Qu, Yan-yan Meng, Hua Chai, Fang Liang, Jia-yi Zhang, Zhu-ye Gao and Da-zhuo Shi

    Citation: European Journal of Medical Research 2018 23:57

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  25. Content type: Research

    Both psoriasis (Ps) and psoriasis arthritis (PsA) have been associated with increased cardiovascular risk. Also, both are characterized by increased neovascularization. Endothelial progenitor cells (EPCs) have...

    Authors: D. Patschan, N. Sugiarto, E. Henze, R. Mößner, J. Mohr, G. A. Müller and S. Patschan

    Citation: European Journal of Medical Research 2018 23:56

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  26. Content type: Research

    The incidence of diabetic atherosclerosis (DA) is increasing worldwide. The study aim was to identify differentially expressed microRNAs (DE-miRs) potentially associated with the initiation and/or progression ...

    Authors: Yuejin Li, Le Xiao, Jinyuan Li, Ping Sun, Lei Shang, Jian Zhang, Quan Zhao, Yiming Ouyang, Linhai Li and Kunmei Gong

    Citation: European Journal of Medical Research 2018 23:55

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  27. Content type: Research

    Many tinnitus scales are available, but all of them have certain limitations. The aim of the current study was to present a psychometric data of a new brief and reliable questionnaire that could be convenientl...

    Authors: Henryk Skarżyński, Elżbieta Gos, Danuta Raj-Koziak and Piotr H. Skarżyński

    Citation: European Journal of Medical Research 2018 23:54

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  28. Content type: Research

    Currently available treatment options for onychomycosis such as topical and systemic antifungals are often of limited efficacy, difficult to administer or associated with relevant side effects. Non-ablative la...

    Authors: G. C. Weber, P. Firouzi, A. M. Baran, E. Bölke, H. Schrumpf, B. A. Buhren, B. Homey and P. A. Gerber

    Citation: European Journal of Medical Research 2018 23:53

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  29. Content type: Research

    A promising novel cell-free bioactive formulation for articular cartilage regeneration, called BIOF2, has recently been tested in pre-clinical trials. The aim of the present study was to evaluate the efficacy ...

    Authors: Ivan Delgado-Enciso, Juan Paz-Garcia, Jose Valtierra-Alvarez, Jorge Preciado-Ramirez, Roman Almeida-Trinidad, Jose Guzman-Esquivel, Martha A. Mendoza-Hernandez, Alberto Garcia-Vega, Alejandro D. Soriano-Hernandez, Jose L. Cortes-Bazan, Hector R. Galvan-Salazar, Ariana Cabrera-Licona, Iram P. Rodriguez-Sanchez, Margarita L. Martinez-Fierro, Josuel Delgado-Enciso and Brenda Paz-Michel

    Citation: European Journal of Medical Research 2018 23:52

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  30. Content type: Research

    The ever growing demand for liver transplantation inevitably necessitates an expansion of the donor pool. Utilization of “shock organs” is considered suboptimal to date while the associated outcome has hardly ...

    Authors: Azin Jafari, Hanno Matthaei, Vittorio Branchi, Edwin Bölke, Rene H. Tolba, Jörg C. Kalff and Steffen Manekeller

    Citation: European Journal of Medical Research 2018 23:51

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  31. Content type: Research

    The primary goal of this study was to analyse the anatomic configuration of the acromio-clavicular joint in a healthy population to be able to develop a classification in a second step. On the basis of the pri...

    Authors: Moritz Crönlein, Lukas Postl, Marc Beirer, Dominik Pförringer, Jennifer Lang, Frederik Greve, Michael Müller, Peter Biberthaler and Chlodwig Kirchhoff

    Citation: European Journal of Medical Research 2018 23:50

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  32. Content type: Review

    To assess the frequency of left atrium/left atrial appendage (LA/LAA) thrombus under treatment with non-vitamin K oral anticoagulants (NOACs) in comparison with vitamin K antagonists (VKAs) in patients with no...

    Authors: Stefan Reers, Georg Karanatsios, Matthias Borowski, Michael Kellner, Michael Reppel and Johannes Waltenberger

    Citation: European Journal of Medical Research 2018 23:49

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  33. Content type: Research

    Many studies have demonstrated that the genetic variants of tumor suppressor gene TP53 contribute to the prediction of breast cancer risk. However, most of them focused on Europeans and Americans; the investigati...

    Authors: Weiming Hao, Xia Xu, Haifeng Shi, Chiyu Zhang and Xiaoxiang Chen

    Citation: European Journal of Medical Research 2018 23:47

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  34. Content type: Research

    There are many approved patient-related outcome measurement tools regarding ankle pathologies. However, there is none incorporating the range of motion (ROM) as an objective parameter. Most instruments focus o...

    Authors: Frederik Greve, Karl Friedrich Braun, Veronika Vitzthum, Michael Zyskowski, Michael Müller, Chlodwig Kirchhoff, Peter Biberthaler and Marc Beirer

    Citation: European Journal of Medical Research 2018 23:46

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  35. Content type: Research

    Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory r...

    Authors: Stephan Alexander Braun, Julia Baran, Holger Schrumpf, Bettina Alexandra Buhren, Edwin Bölke, Bernhard Homey and Peter Arne Gerber

    Citation: European Journal of Medical Research 2018 23:45

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  36. Content type: Research

    Data on PNM elastase levels in cerebrospinal fluid following traumatic brain injury (TBI) in humans are not available in the literature. Therefore, the aim of this prospective study was to evaluate the dynamic...

    Authors: Lukas Kurt Postl, Viktoria Bogner, Martijn van Griensven, Marc Beirer, Karl Georg Kanz, Christoph Egginger, Peter Biberthaler and Chlodwig Kirchhoff

    Citation: European Journal of Medical Research 2018 23:44

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  37. Content type: Research

    Chondral or osteochondral lesions, post-traumatic contracture and loose bodies of the elbow are often associated with chronic pain, stiffness, repetitive swelling and joint blockages. Therefore, arthroscopy of...

    Authors: Jörg Nowotny, Sebastian Löbstein, Achim Biewener, Guido Fitze and Philip Kasten

    Citation: European Journal of Medical Research 2018 23:42

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  38. Content type: Research

    The coracoid process plays an important role in maintaining the stability of the elbow joint. A fracture of the coronoid process is often treated via surgical approaches, including open reduction and internal ...

    Authors: Hong-Wei Chen and Xiao-Feng Teng

    Citation: European Journal of Medical Research 2018 23:40

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  39. Content type: Research

    Reduction of femoral shaft fractures remains a challenging problem in orthopaedic surgery. Robot-assisted reduction might ease reduction and fracture treatment. However, the influence of different reduction pa...

    Authors: Benedikt Peterburs, Anke Mittelstaedt, Philipp Haas, Maximilian Petri, Ralf Westphal, Christian Dullin, Stephan Sehmisch and Claudia Neunaber

    Citation: European Journal of Medical Research 2018 23:39

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  40. Content type: Research

    Ischemia of intestinal organs is a main cause of complications in surgical intensive care patients. Changes in the tonus of arteries contributing to vascular resistance play an important role in the determinat...

    Authors: J. Westhoff, K. Weismüller, C. Koch, V. Mann, M. A. Weigand and M. Henrich

    Citation: European Journal of Medical Research 2018 23:38

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  41. Content type: Research

    Hyaluronidase is a hyaluronic acid (HA) metabolizing enzyme, which is approved as an adjuvant for infiltration anesthesia. The “off-label” use of hyaluronidase is regarded as gold standard for the management o...

    Authors: Bettina Alexandra Buhren, Holger Schrumpf, Edwin Bölke, Kai Kammers and Peter Arne Gerber

    Citation: European Journal of Medical Research 2018 23:37

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  42. Content type: Research

    A novel software (“Dynamic Coronary Roadmap”) was developed, which offers a real-time, dynamic overlay of the coronary tree on fluoroscopy. Once the roadmap has been automatically generated during angiography ...

    Authors: Kerstin Piayda, Laura Kleinebrecht, Shazia Afzal, Roland Bullens, Iris ter Horst, Amin Polzin, Verena Veulemans, Lisa Dannenberg, Anna Christina Wimmer, Christian Jung, Florian Bönner, Malte Kelm, Katharina Hellhammer and Tobias Zeus

    Citation: European Journal of Medical Research 2018 23:36

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  43. Content type: Research

    Bony avulsion fractures of the distal phalanges can result in mallet finger deformity if not treated appropriately. Therefore, only minimally displaced fractures can be treated conservatively with a good outco...

    Authors: H. Vester, L. Schul, F. von Matthey, M. Beirer, M. van Griensven and S. Deiler

    Citation: European Journal of Medical Research 2018 23:35

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  44. Content type: Review

    It is reported that glutathione S-transferase mu (GSTM1) polymorphism is associated with non-viral hepatic cirrhosis (HC). However, some studies showed different views. Therefore, in this paper, a meta-analysis w...

    Authors: Ye Gu, Jing Zhao, Li Ao, Jianning Ma, Kena Bao, Min Liu and Weiping Huang

    Citation: European Journal of Medical Research 2018 23:34

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