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Table 2 Pulmonary Gas Exchange and Hemodynamics

From: Serum heparan sulfate levels are elevated in endotoxemia

   Time Point of Measurement  
  Baseline 3 h after Endotoxin 6 h after Endotoxin
PaO2, [mmHg]    
Endotoxin* 572.2 ± 36.1 342.1 ± 113.5# 225.2 ± 157.7#
Control 603.1 ± 42,2 610.4 ± 48.6 628.2 ± 41.2
PaCO2 [mmHg]    
Endotoxin* 34.4 ± 7.8 48.1 ± 7.4# 62.1 ± 18.5#
Control 30.5 ± 5.6 28.0 ± 5.1 28.7 ± 5.8
Minute ventilation [ml/kg.min]    
Endotoxin 223.1 ± 43.8 244.9 ± 30.8 234.9 ± 57.9
Control 224.9 ± 50.5 219.4 ± 41.6 221.0 ± 49.3
Peak airway pressure [mbar]    
Endotoxin* 26.4 ± 3.3 37.6 ± 3.9 53.6 ± 10.7#
Control* 29.4 ± 2.4 32.0 ± 2.8 36.9 ± 5.2
Norepinephrine requirements [mg/h]    
Endotoxin 0.15 ± 0.09# 0.05 ± 0.04 0.15 ± 0.12#
Control 0.0 0.0 0.0
MAP [mmHg]    
Endotoxin 72.3 ± 7.3 67.0 ± 9.2 67.6 ± 11.3
Control 90.1 ± 12.2 82.1 ± 9.6 72.5 ± 8.4
Heart Rate [min-1]    
Endotoxin* 86 ± 17 110 ± 17 124 ± 20#
Control* 90 ± 12 82 ± 9 78 ± 13
LVEDP [mmHg]    
Endotoxin 9.0 ± 1.2 9.1 ± 1.3 9.0 ± 2.1
Control 8.4 ± 0.2 8.3 ± 0.7 8.3 ± 0.4
  1. * Significant changes over time within a group (p < 0.05). # Significant differences between groups at the referring time points of measurement (p < 0.05).
  2. PaO2: Arterial oxygen tension; PaCO2: Arterial carbondioxid tension; MAP: Mean arterial blood pressure; LVEDP: Left ventricular enddiastolic blood pressure