|
Wenerowicz, 1978 [15]
|
19
|
PB
|
60
|
P > 4.5 mg/dl PSR (questionnaire)
|
Patients with internal locus of control1 orientation showed higher compliance than with external locus
|
|
Cummings, 1982 [51]
|
116
|
PB
|
70
|
P > 5.5 mg/dl PSR (interview)
|
Situational factors and psychosocial variables major contributors to adherence
|
|
Betts, 1988 [52]
|
46
|
PB
|
74
|
P > 5 mg/dl PSR (questionnaire)
|
Length of time on HD, age, educational level and response to illness not significantly related to adherence
|
|
Weed-Collins, 1989 [22]
|
30
|
PB
|
64
|
P > 5.5 mg/dl PSR (questionnaire)
|
Perceived barriers ("forgetting" and "being away from home") most significant predictors of compliance, women significantly more compliant
|
|
Blanchard, 1990 [53]
|
40
|
PB, CAS, Vits
|
28
|
PSR (questionnaire)
|
Majority of HD patients knew dosing schedules but knowledge about drug treatment was grossly deficient
|
|
Bame, 1993 [23]
|
1230
|
PB, AHT, CAS
|
50
|
P > 6.0 mg/dl
|
Prevalence of noncompliance consistent with previous studies; older age and higher income associated with compliance
|
|
Kaplan, 1994 [7]
|
30
|
PB, AHT
|
67
|
PSR (questionnaire) Reporting missing a dose
|
Drug selection and medication compliance contained greatest number of potential problems
|
|
Cleary, 1995 [18]
|
51
|
AHT, PB, CAS, Vits
|
61
|
P > 4.5 mg/dl (interview)
|
Patients with long-term HD more compliant with AHT and CAS than with PB
|
|
Lin, 1997 [54]
|
86
|
PB, CAS
|
24 - 61
|
P > 4.59 mg/dl, PSR, nurses' assessment
|
Multidimensional Health Locus of Control (MHLC) scale had only slight influence on measures of compliance
|
|
Curtin, 1997 [17]
|
135
|
AHT, PB
|
42 - 80
|
MEMS
|
Patients ≤ 65 yrs made more dosing errors with AHT and missed taking PB on more days than patients > 65 yrs
|
|
Leggat, 1998 [16]
|
6251
|
PB
|
22
|
P > 7.5 mg/dl
|
Younger patients and smokers with higher rates of noncompliance; blacks significantly less noncompliant than whites
|
|
Curtin, 1999 [6]
|
135
|
AHT, PB
|
73
|
PSR, pill count, MEMS
|
African-Americans with higher rates of noncompliance
|
|
Caraballo Nazario, 2001 [19]
|
53
|
AHT, PB, CAS
|
75
|
PSR, Reporting missing a dose (structured interview)
|
Significant association between compliance and educational level
|
|
Horne, 2001 [55]
|
47
|
AHT, PB, CAS
|
57
|
PSR, Reporting missing a dose (self report)
|
Nonadherence correlated with concerns about potential adverse effects of medication
|
|
Tomasello, 2004 [56]
|
129
|
PB
|
38-51
|
PSR (taking < 80% of medication), P > 5.5 mg/dl
|
Compliance did not account for the large difference in prescribed pill burden
|
|
Rahman, 2004 [57]
|
205
|
AHT
|
23
|
PSR, Reporting missing a dose
|
Good adherence to AHT therapy
|
|
Holley, 2006 [20]
|
39
|
AHT, PB
|
21
|
PSR, Reporting missing a dose (structured interview)
|
Inadequate prescription coverage, lack of transportation, and medication cost contribute to noncompliance
|
|
Lindberg, 2007 [58]
|
144
|
AHT, PB, CAS, Vits
|
80
|
Discrepancy between self-report and medication list
|
Deviation between consumption and prescription in chronic HD patients
|
|
Hirth, 2008 [21]
|
5478
|
AHT, PB, CAS
|
3 *-29 **
|
Reporting costrelated nonadherence (questionnaire)
|
Cost-related nonadherence varies across countries, substantial international variation
|
