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Table 3 A - Low and High fasting urinary (U) MDA excretion, plasma (P) concentration of uric acid, ratio U-MDA/P-Uric acid; B-Ca saltcrystal nucleation and other data in postprandialurine; C - complementary data from fasting period

From: Idiopathic Recurrent Calcium Urolithiasis (IRCU): variation of fasting urinary protein is a window to pathophysiology or simple consequence of renal stones in situ? A tripartite study in male patients providing insight into oxidative metabolism as possible driving force towards alteration of urine composition, calcium salt crystallization and stone formation*

 

A

B

     

C

    
 

FASTING

POSTPRANDIAL

    

COMPLEMENTARY

   
 

Low x

T-Ox a

T-Ca b

T-Ca/

pH c

CaOx

HAP

FE-N-Alb-P

U-Volume

U-Na

Insulin

BMI

 

High xx

  

10 2 × T-Ox

        
  

mM/l

mM/l

  

ΔG

ΔG

% × 10 3

ml

mM

μU/ml

kg/(m) 2

U-MDA; nM1)

89(2);88

0.52(0.03);25 24(3);20

0.51(0.08);20

5.46(0.09);29 1.3(0.1);84

3.1(0.3);84

1.5(0.1);85

167(13);88

11(0.5);88

16(1);86

26.0(0.3);88

 

175(5);88

0.53(0.03);35 20(3);26

0.44(0.07);26

5.57(0.08);44 0.5(0.1);80

2.7(0.3);80

2.9(0.6);85

283(17);88

14(0.8);88

18(1);87

26.7(0.4);88

p

< 0.001

0.41d

0.18d

0.23d

0.17

< 0.001

0.17

0.002d

< 0.001

< 0.001

0.15

0.08

P-Uric acid;

301(10);94

0.54(0.03);30 16(2);25

0.34(0.06);25

5.72(0.10);36 0.8(0.1);88

3.5(0.3);88

2.9(0.6);91

252(17);94

13(0.6);94

14(1);93

25.4(0.3);94

μM -1-1 2)

425(10);93

0.52(0.02);33 27(3);24

0.59(0.08);24

5.35(0.07);43 1.0(0.1);84

2.1(0.3);84

1.5(0.1);90

197(14);93

12(0.7);93

18(1);91

27.2(0.3);93

p

< 0.001

0.29d

0.007d

0.007d

0.001

0.18

0.001

< 0.008d

0.007

0.03

0.003d

< 0.001

U-MDA/P-Uric acid;

244(6);88

0.52(0.03);27 25(3);20

0.55(0.09);20

5.41(0.08);33 1.3(0.1);78

2.8(0.4);78

1.4(0.1);85

157(12);88

11(0.5);88

17(1);86

26.6(0.3);88

nM/mM -l-1 3)

525(18);88

0.54(0.03);33 19(3);26

0.41(0.06);26

5.62(0.08);40 0.6(0.1);86

3.0(0.3);86

3.0(0.7);88

293(17);88

14(0.8);88

16(1);87

26.1(0.4);88

P

< 0.001

0.26d

0.09d

0.13d

0.04

< 0.001

0.38

< 0.001d

< 0.001

< 0.001

0.18

0.13

  1. Mean values (SE), followed by number of observations. For further information see Table 2 and text.
  2. x, xx: indicate ≤ and > median, respectively; 1), 2), 3): medians are 123, 349 and 337, respectively; a: at original pH; b: at prefixed urine pH 6.0; c: original urine pH; d: based on log10 data.